Connecting Probes; Connecting The Esi Probe To The Ms Detector; Chapter 2 Connecting Probes - Thermo Scientific LCQ Fleet Getting Started Manual

Connecting Probes

Connecting the ESI Probe to the MS Detector

Thermo Scientific
This chapter describes how to connect an ion source probe to the LTQ Series MS detector.
Contents
• Connecting the ESI Probe to the MS Detector
• Connecting the APCI Probe to the MS Detector
To connect liquid lines to the electrospray ionization (ESI) probe
1. Install the Ion Max source housing and ESI probe onto the LTQ Series MS detector as
described in the Ion Max and Ion Max-S API Source Hardware Manual.
2. Install liquid lines between the divert/inject valve, the LC system, the syringe pump, and
the grounding union, as appropriate for your application. For more information, see
Chapter 6, "Connecting the Inlet Plumbing."
3. Connect the 1-in. ID Tygon™ tubing (P/N 00301-22922) to the source housing drain.
4. Insert the other end of the tubing into a waste container, and vent the waste container to
a fume exhaust system.
CAUTION Prevent solvent waste from backing up into the API source and mass
spectrometer. Always ensure that the PVC drain tubing is above the level of liquid in
the waste container.
Do not vent the PVC drain tube connected to the waste container to the same fume
exhaust system to which you have connected the forepump. Connecting the API
source drain tube and the forepump exhaust to the same fume exhaust system is likely
to contaminate the analyzer optics.
Equip your laboratory with at least two independent fume exhaust systems. Route the
(blue) exhaust tubing from the forepump to a dedicated fume exhaust system. Route
the PVC drain tube from the API source to the waste container. Vent the waste
container to a dedicated fume exhaust system that is independent from that used for
exhausting the forepump.
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LTQ Series Getting Connected Guide 11