Modification, replacement, by-passing, and/or adding any electrical component without the written consent of Thermo Scientific voids any/all warranties, ETL/CE certification(s) and liabilities. WARNING: Static electricity may build up in BPCs.
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The safety cap on drive shaft motor must never be removed and must always be locked in place during use. If the safety cap is broken, call Thermo Scientific service personnel to replace it prior to use. WARNING: Follow lockout/tagout procedures.
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(j) installation, removal, use, maintenance, storage, or handling in an improper, inadequate, or unapproved manner, such as, but not limited to, failure to follow the documentation or instructions in the deliverables or related to Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
The accuracy of the information in this publication and your satisfaction with the scope and content of this publication are important to us. Please send any corrections or suggestions you have for this user's guide (or for any other Thermo Scientific technical publication) to TechnicalDocumentation@ThermoFisher.com. Related publications Please contact your local sales representative for information about the related publications listed below.
(S.U.M.) offers a single-use alternative for traditional stirred tank mixing. It is designed using the same mixing principles as the stainless steel Thermo Scientific S.U.M. Both systems use an impeller linked to an overhead mixing motor, and a sealed bearing assembly which allows the impeller to turn while maintaining the integrity of the system.
Docking station base with locking casters in the rear • Adjustable handle that can be locked in position or stored away • Mast support structure that houses the main control unit Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
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Tubing for liquid transfer Available options include: • Open-top liner for media or buffer preparation • Impeller sleeve with quick connect fitting (used with the reusable bearing hub in open-top mixing applications) Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
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10° angle. On adjustable motor head models, the angle of the adjustable motor head may be changed. The adjustable motor head option enables fixing the motor head at an angle in 5° increments from 0–30°. Figure 1.5. Motor head Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
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The mixing motor assembly is a directly coupled drive assembly that supplies power to the drive shaft and impeller to initiate the mixing process. The mixing motor assembly is made up of the parts shown in Figure 1.8. Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
A reusable bearing hub is used for all open-top mixing applications. A quick connect fitting is used to connect the drive shaft sleeve to the bearing hub. Figure 1.9. Open‑top liner Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
Manipulation of the BPC as the last few liters of liquid are removed can minimize liquid hold-up. Liquid hold-up is 100 ml for 50, 100, and 200 L containers, and 500 ml for 300 L containers. Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
Setup and operating information Chapter contents Site preparation Initial setup Docking station preparation BPC preparation and setup BPC loading Operating information Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
The DS 300 S.U.M. will arrive crated. Follow the provided unpacking instructions (DOC0010) in addition to the following instructions. Note: When uncrating hardware, retain all packing materials for possible future use. Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
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2. Swing the crate door down. The door will create a ramp for moving items in and out (Figure 2.2). Figure 2.2. Open DS 300 S.U.M. crate Support brace Crate door and ramp Tools Drive shafts Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
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7. Remove the strap that secures the mixer to the eyes screwed into the bottom of the crate (Figure 2.4). Figure 2.4. Removing the bottom strap Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
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The handheld control unit is wrapped separately and attached to the side of the handle. Use caution when cutting the packaging material from the device. Then hang the handheld device on the hook (Figure 2.8). Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
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14. Place the bearing hub, torque wrench, and spanner wrench into the appropriate storage holes on the docking station unit. Place the drive shaft(s) in the appropriate storage holder(s) on the docking station. Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
DS 300. The unit should be plugged into a minimum 8 amp outlet. 3. Engage the caster brakes on the rear wheels of the docking station (Figure 2.11). Figure 2.11. Locking the rear wheels Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
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8. Engage the E-Stop button on the top of the handheld control device by turning the red button in the direction of the arrows (Figure 2.13). When engaged, the button will be slightly elevated. Figure 2.13. Engaging the E‑Stop button Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
Carefully coil tubing on top of the BPC to prevent puncturing the BPC with cable ties or clamps. Use cushioning between tubing and BPC in storage and transport. Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
3. A 50 L BPC may be used in a 100 L drum, if desired. To use this configuration, ensure that the white plastic spacer is placed in the bottom of the 100 L drum, under the conical insert (Figure 2.15). Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
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8. Insert the drain line through the hole in the bottom of the conical drum insert (Figure 2.16). Figure 2.16. Inserting the drain line through the hole in the bottom of the drum Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
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Note: To properly place the drum under the docking station, the motor head may need to be lifted. To operate the lift mechanism, see section 2.6.2. Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
4. Carefully unpack the BPC from its two protective polybags. The easy-to-use safety blade polybag opener (available from Thermo Fisher Scientific) is one option. Do not use scissors or a knife to remove the polybag as this may damage the BPC. Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
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12. Remove the protective black cap from the bearing port and slide the port into the receiver of the motor mount block and lock into place with the retention clamp (Figure 2.22). Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
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15. If your unit is equipped with the optional drum positioner, use it to secure the drum and dolly in place with the supplied strap (Figure 2.23). Figure 2.23. Securing the drum and dolly to the positioner with the strap Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
CAUTION: When raising and lowering the mixing head, caution should be used to avoid pinching or crushing an operator or damaging the equipment or the single-use liner. Figure 2.24. Adjusting the height using the handheld control device Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
A reusable bearing hub is needed when using open-top containers. Use the following steps to insert the reusable hub. 1. Open the latching mechanism under the motor head and slide the hub into the holder (Figure 2.26). Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
1. Remove the latch pin from the safety cover on the motor and lift the clear plastic safety cover (Figure 2.28). Figure 2.28. Removing the motor head latch pin and safety cover Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
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• When approximately 5.1 cm (2 in.) of shaft remains, twist slightly to engage the impeller (Figure 2.31). Figure 2.30. Drive shaft sleeve installation Figure 2.31. Inserting the drive shaft Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
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150 in-lb. • Remove the wrenches and place them in storage holders. • Close the safety cover and insert the latch pin. Figure 2.33. Coupling the drive shaft to the motor drive Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
(Figure 2.34). Note: In the event of an emergency, use the red E-Stop button on the top of the handheld control device to shut off power to the motor and handheld control device. Figure 2.34. Controlling the speed Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
If the drive shaft becomes difficult to turn, lightly coat the drive cap threads with food-grade anti-seize. It is a good idea to have spare parts on hand. See section 4.5 for more information. Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
E-Box. Issue: The rpm display on the handheld control device is inaccurate. Cause/solution: The motor needs to be calibrated. Contact Thermo Scientific support personnel. Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
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Reload the BPC using the instructions provided in Chapter 2. Issue: The motor has been calibrated improperly. Cause/solution: Contact Thermo Scientific support personnel. Issue: There is excess tension in the film near the bearing port of the loaded BPC. Cause/solution: If possible, reload the BPC by carefully following the instructions provided in Chapter 2.
Specifications and part numbers Chapter contents Hardware features and specifications BPC specifications General mixing specifications Part numbers for components, parts, and accessories Part numbers for replacement and spare parts Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
Impeller material USP Class VI, HDPE Impeller sleeve with quick connect ™ C-Flex Open-top mixing liner Chamber made of CX 3-9 film Closed-top mixing BPC Chamber made of CX 5-14 film Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
12.7 mm (1/2 in.) x 19.1 mm (3/4 in.) x 30.5 cm (12.01 in.) and line polycarbonate quick connect 12.7 mm 12.7 mm (1/2 in.) x 19.1 mm (3/4 in.) x 0.61 m (2 ft.) (1/2 in.) insert (MPX) and cap Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
1/2 in. left ≈ 2 1/2 in. ≈ 15.74 in. 10° 79 L 4:1* 500 mL 300 L drum * 5:1 turndown ratio can be achieved using the adjustable angle motor head Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
Table 4.5. Country‑specific electrical plug part numbers. Country Cat. no. Europe SV50177.345 SV50177.346 China SV50177.347 US (110 VAC) SV50177.348 US (208 VAC) SV50177.349 India SV50177.350 Italy, Chile SV50177.351 Brazil, Switzerland SV50177.352 Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
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50 L 66.3 cm (26.1 in.) SV50959.03 100 L 84.1 cm (33.1 in.) SV50959.01 200 L 108 cm (42.5 in.) SV50959.02 300 L 129.5 cm (51 in.) SV50177.49 Figure 4.6. Drive shaft Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
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77 cm (30.3 in.) SH30749.13 108 cm (42.5 in.) Impeller, sleeve, and connector for 300 L 96 cm (37.8 in.) SH30749.08 129.5 cm (51 in.) Figure 4.8. Impeller, sleeve, and connector for open‑top liners Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
SV50177.124 Surface mount latch SV50177.121 3/8 in. x 150 in-lb. Square torque wrench SV50177.11 Wrench SV50177.10 Motor safety cap SV50177.06 50 L drive shaft safety cap SV50177.90 Common motor sleeve SV50177A.03 Thermo Scientific HyPerforma DS 300 Single‑Use Mixer User's Guide...
General ordering information Chapter contents Ordering instructions Ordering/support contact information Technical support information HyPerforma DS 300 Single‑Use Mixer User's Guide Thermo Scientific...
Some or all of the following may be appropriate, depending on individual experience and circumstances. Technical service hotline and email Contact your Thermo Scientific sales representative for general product pricing, availability, delivery, order information, and product complaints. Call +1 435 792 8500 (United States) or +44 (1) 670 734 093 (Europe, U.K.) for direct and immediate response to overall product questions,...
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