Internal Reference Mass Correction - Agilent Technologies Revident LC/Q-TOF System User Manual

4 Basic Operation

Internal Reference Mass Correction

Internal Reference Mass Correction

In addition to manual calibration and calibration during autotune, the mass can
also be automatically corrected during a run, referred to as using an Internal
Reference Mass (IRM).
This procedure consists of introducing a mass reference standard into the
source during a run via a reference sprayer valve available on dual AJS and dual
ESI sources. The reference masses contained in the reference standard are used
to automatically correct each acquired spectrum. The mass correction affects
the current sample only and is not applied to future samples run.
For APCI ion sources, the UIRM-hardware kit (Universal Internal Reference Mass)
should be used (part number G1969-67400).
1 To display the Method Editor window, click Method Editor in the windows
2 Select the MS Q-TOF tab.
3 Select the Method > Source > Ref Mass section, and set the following
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section on the Ribbon. Or, click the Method layout in the Ribbon.
parameters:
• Select Enable Ref Mass correction.
• Select Use Bottle A.
Agilent Revident LC/Q-TOF System User Guide