Comparing Supercritical Fluid Properties To Those Of Other Solvents; System Configurations - Waters ACQUITY UPC2 System Manual

1.1.1 Comparing supercritical fluid properties to those of other
solvents
Supercritical CO
compared to liquid CO
gases. Diffusivities of solutes in supercritical CO
diffusivities in liquid solvents. Because supercritical fluid properties are pressure-dependent near
the critical point, they are highly tunable solvents.
Table 1–1:
Solvent
Supercritical CO
Liquids
Gases
Recommendation:
flow pressure of 6,205 to 7,584 kPa (62 to 76 bar, 900 to 1100 psi).
1.2

System configurations

The following illustrations show the four core configurations that comprise the ACQUITY UPC
system. A system configuration can differ according to the number and type of modules it contains.
For example, if a system includes a mass spectrometer, the system modules can be arranged as
two or three separate stacks.
fluid has a lower viscosity, higher diffusion rate, and no surface tension when
2
. Supercritical CO
2
Solvent viscosity comparison
fluid
2
Use only food-grade, or better, house-supplied CO
November 16, 2016, 715004521 Rev. C
physical properties are between those of liquids and
2
are by as much as a factor of 10 higher than their
2
Viscosity range
20-100 µPa.s (0.02-0.1 cP)
500-1000 µPa.s (0.5-1.0 cP)
10 µPa.s (0.01 cP)
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or non-siphon CO at a
2 2
2