Treatment Methods; Basic Concepts - Profound Sonalleve MR-HIFU Instructions For Use Manual

4. Treatment methods > 4.1. Basic concepts
This chapter explains the terms and concepts necessary for understanding the Sonalleve MR-HIFU
treatment workflow.

4.1. Basic concepts

In High Intensity Focused Ultrasound (HIFU) treatment, an ultrasound beam is focused on a small
volume within the target tissue. This is called a sonication, and it causes the temperature to rise
which coagulates the tissue. With this technique, unwanted tissue can be destroyed without
invasive surgery.
MR-guided HIFU (MR-HIFU) treatment, also known as MR-guided focused ultrasound therapy
(MRgFUS), is based on monitoring the relative temperature change during the sonication treatment
using MRI.
The MR images are used to calculate relative temperature maps, which are monitored on the
Sonalleve console. These temperature maps are used to visualize the progress of the treatment,
and they also can be used to control the duration of the sonication. The following table explains the
basic terms and concepts that you need to be familiar with when working with the Sonalleve MR-
HIFU system.
Tab. 6: Sonalleve MR-HIFU key terms and definitions.
Term
Autopopulation Automated treatment cell planning. The action of automatically filling a
Available
Target Area
(ATA)
Instructions for Use
109745C2 / 02-2022
MR scanner
Fig. 17: The basic principles of HIFU.
Definition
defined region with treatment cells.
The area which is within reach of the ultrasound beam and within which
treatment cells can be positioned.

4. Treatment methods

MR coil
Focused ultrasound waves
45 (192)