Chapter 7 Troubleshooting - Thermo Scientific ETD Getting Started Manual

For the ltq xl and ltq velos ms detectors (compatible with ltq orbitrap xl and ltq orbitrap velos)

Table of Contents

Troubleshooting

Thermo Scientific

The MS/ETD System uses the following consumables:

• Filament

• Fluoranthene

• Ion volume

After a period of time, you might need to replenish the ETD fluoranthene reagent, replace the

filament, and clean or replace the ion volume. As the consumables are depleted, the ETD

reagent m/z peak intensity diminishes (m/z = 202 in negative polarity mode). Periodically

checking this peak intensity is a good way to monitor the ETD module consumables. To view

the ETD reagent m/z signal, follow the procedure in

page

28.

Tip Expect the filament and ion volume to last for about 400 to 500 hours of operation,

and a vial of fluoranthene reagent to last for several months or more.

Table 3

lists some ETD module problems, their causes, and their possible solutions.

"Turning On the Reagent Ion Source"

MS/ETD System Getting Started Guide

Table of Contents

Troubleshooting