Agilent Technologies 1290 Infinity User Manual page 81

Stainless Steel (ST)
Stainless steel is inert against many common solvents. It is stable in the
presence of acids and bases in a pH range of 1 to 12.5. It can be corroded by
acids below pH 2.3. It can also corrode in following solvents:
• Solutions of alkali halides, their respective acids (for example, lithium
• High concentrations of inorganic acids like nitric acid, sulfuric acid and
• Halogenated solvents or mixtures which form radicals and/or acids, for
• Chromatographic grade ethers, which can contain peroxides (for example,
• Solutions of organic acids (acetic acid, formic acid, and so on) in organic
• Solutions containing strong complexing agents (for example, EDTA,
• Mixtures of carbon tetrachloride with 2-propanol or THF.
Titanium (Ti)
Titanium is highly resistant to oxidizing acids (for example, nitric, perchloric
and hypochlorous acid) over a wide range of concentrations and temperatures.
This is due to a thin oxide layer on the surface, which is stabilized by oxidizing
compounds. Non-oxidizing acids (for example, hydrochloric, sulfuric and
phosphoric acid) can cause slight corrosion, which increases with acid
concentration and temperature. For example, the corrosion rate with 3 % HCl
(about pH 0.1) at room temperature is about 13 μm/year. At room
temperature, titanium is resistant to concentrations of about 5 % sulfuric acid
(about pH 0.3). Addition of nitric acid to hydrochloric or sulfuric acids
1290 Infinity Quaternary Pump User Manual
iodide, potassium chloride, and so on) and aqueous solutions of halogens.
organic solvents especially at higher temperatures (replace, if your
chromatography method allows, by phosphoric acid or phosphate buffer
which are less corrosive against stainless steel).
example:
→ 2 COCl
2 CHCl + O
3 2
This reaction, in which stainless steel probably acts as a catalyst, occurs
quickly with dried chloroform if the drying process removes the stabilizing
alcohol.
THF, dioxane, diisopropylether). Such ethers should be filtered through dry
aluminium oxide which adsorbs the peroxides.
solvents. For example, a 1 % solution of acetic acid in methanol will attack
steel.
ethylene diamine tetra-acetic acid).
+ 2 HCl
2
Using the Module
Solvent Information
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