Placing The System In Standby Condition; Cleaning The Ion Sweep Cone And Ion Transfer Tube - Thermo Scientific TSQ Series Hardware Manual

6. Set up and start a flow of 50:50 methanol/water solution from the LC to the API source,
as follows:
a. In the Tune Master window, choose Setup > Inlet Direct Control. The Inlet Direct
b. Click the LC tab.
c. Set the flow rate to a value that is typical for your experiments.
d. Set the solvent proportions to 50% methanol and water.
e. Click the Start (
7. Let the solution flow through the sample transfer line, sample tube, and API probe for
15 minutes. After 15 minutes, turn off the flow of liquid from the LC to the API source, as
follows: Leave the API source (including the APCI vaporizer, sheath gas, and auxiliary gas) on
for an additional 5 minutes. Click the Stop (
8. After 5 minutes, turn off the API source by placing the mass spectrometer in standby: From
the Tune Master window, choose Control > Standby (or click the On/Standby button) to put
the mass spectrometer in standby.
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Placing the System in Standby Condition

To place the TSQ system in standby condition
1. From the Tune Master window, choose Control > Standby (or click the On/Standby button)
to put the mass spectrometer in standby. The System LED on the front panel of the mass
spectrometer is illuminated yellow when the system is in standby.
2. Leave the mass spectrometer power on.
3. Leave the LC power on.
4. Leave the autosampler power on.
5. Leave the data system power on.
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Cleaning the Ion Sweep Cone and Ion Transfer Tube

You must clean the ion sweep cone and the ion transfer tube on a regular basis to prevent corrosion
and to maintain optimum performance of your API source. If you use nonvolatile buffers in your
solvent system or high concentrations of sample, you might need to clean the ion sweep cone and
ion transfer tube more often.
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Control view appears.
) button to start the LC pump.
"Placing the System in Standby Condition."
"Cleaning the Ion Sweep Cone and Ion Transfer Tube."
"Maintaining the Ion Sweep Cone and Ion Transfer Tube"
"Emptying the Solvent Waste Bottle."
Things to Do After Operating the TSQ System
) button to stop the LC pump.
on page
TSQ Series Hardware Manual
4
Daily Operation
70.
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