Fixed-angle rotor assembly for use in beckman coulter avanti jxn series centrifuges only (40 pages)
Summary of Contents for Beckman Coulter Avanti JXN-26
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User Guide Avanti JXN Series High Performance Centrifuges For In Vitro Diagnostic Use PN B38322AA February 2014 Beckman Coulter, Inc. 250 S. Kraemer Blvd. Brea, CA 92821 U.S.A.
Initial Release This document applies to the latest software listed and higher versions. When a subsequent software version affects the information in this document, a new issue will be released to the Beckman Coulter Web site. For labeling updates, go to www.beckmancoulter.com...
Beckman Coulter Representative. Beckman Coulter, Inc. urges its customers and employees to comply with all national health and safety standards such as the use of barrier protection. This may include, but is not limited to, protective eyewear, gloves, and suitable laboratory attire when operating or maintaining this or any other automated laboratory analyzer.
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• This equipment is used in a manner other than specified. Operate the instrument as instructed in the Product Manuals. • You introduce software that is not authorized by Beckman Coulter into your computer. Only operate your system’s computer with software authorized by Beckman Coulter.
Installation CAUTION This instrument is designed to be installed by your Beckman Coulter Representative. Installation by anyone other than authorized Beckman Coulter personnel invalidates any warranty covering the instrument. Also, should the instrument need to be moved, your Beckman Coulter Representative must reinstall and re-level the instrument in its new location.
Fuse Replacement WARNING Fuses protect certain electrical circuits within this instrument against overcurrent conditions. The fuse is not customer replaceable. For continued protections, please contact your Beckman Coulter Representative. viii PN B38322AA...
Mechanical Safety DANGER For safe operation of the equipment, observe the following: • Use only the Beckman Coulter rotors and accessories designed for use in this instrument. • Do not exceed the maximum rated speed of the rotor in use.
Safety Notice Summary of Instrument Labels Precautions with Liquids CAUTION Risk of instrument damage. Do not place containers holding liquid on or near the chamber door. Liquid, if spilled, may get into the instrument and damage electrical or mechanical components. Volatile Liquids DANGER This instrument is not designed for use with materials capable of developing...
Safety Notice Summary of Instrument Labels China RoHS Caution Label This label indicates that the electronic information product contains certain toxic or hazardous substances. The center number is the Environmentally Friendly Use Period (EFUP) date, and indicates the number of calendar years the product can be in operation. Upon the expiration of the EFUP, the product must be immediately recycled.
For Beckman Coulter products bearing this label, please contact your dealer or local Beckman Coulter office for details on the take-back program that will facilitate the proper collection, treatment, recovery, recycling and safe disposal of the device.
Operation, replacement or servicing of any components where contact with bare, live hazardous parts could occur, possibly resulting in electric shock, should only be performed by your Beckman Coulter representative. Protective Ground This symbol is used to indicate a protective ground. This instrument must be properly grounded.
Contents Revision History, iii Safety Notice, v Alerts for Danger, Warning, Caution, Important, and Note, v Safety Notices, vii Installation, vii Replacement Parts, vii Service, viii Power Supply, viii Fuse Replacement, viii Mechanical Safety, ix Chemical and Biological Safety, ix Precautions with Liquids, x Volatile...
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Contents CFC-Free Centrifugation, xxix Software Copyright, xxix Symbols, xxx Graphics, xxxi CHAPTER 1: Description, 1-1 Overview, 1-1 For In Vitro Diagnostic Use, 1-1 Centrifuge Function, 1-2 Touch Screen, 1-2 Name Rating Plate, 1-2 Housing and Door, 1-3 Rotor Chamber, 1-3 Friction Reduction System (FRS), 1-3 Drive, 1-3...
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Contents Item Help, 2-6 Global Help, 2-6 Exit from Help, 2-8 About Your Instrument, 2-8 CHAPTER 3: Operations, 3-1 Overview, 3-1 Manual Operation, 3-1 Step 1: Start on the Home Page, 3-2 Step 2: Set the Speed and Rotor, 3-3 Step 3: Set the Acceleration and Deceleration Profiles, 3-4 Step 4: Set the...
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Contents Enabling Auto Print , 4-16 Enabling Auto Export, 4-16 Enabling Run Comments, 4-17 E-Signature, 4-18 CHAPTER 5: Programs, 5-1 Overview, 5-1 Creating Programs, 5-2 Running Programs, 5-6 Editing Programs, 5-7 Deleting Programs, 5-8 CHAPTER 6: Functional Pages, 6-1 Overview, 6-1 Home Page, 6-3 Home Page (Run in...
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Contents Run History Filter Page, 6-27 Before Run/After Run Comment Page, 6-28 Menu Page, 6-29 System Options Page, 6-30 The Basic Tab, 6-30 The System Tab, 6-31 The Network Tab, 6-32 The Users Tab, 6-33 The Reports Tab, 6-34 Select Language Page, 6-35 User Options Page, 6-36...
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Contents Field Service, 7-1 Maintenance, 7-1 Cleaning, 7-2 Tube Breakage, 7-3 Decontamination, 7-3 Sterilization and Disinfection, 7-4 Replacing the Air Filter, 7-4 Checking the Vacuum Pump, 7-5 Diagnostics/User Messages, 7-6 Accessing the Rotor in Case of Power Failure, 7-6 JCF-Z Rotor Identification, 7-11 Storage and Transportation, 7-12...
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Contents Abbreviations Index Beckman Coulter, Inc. Avanti JXN Series Centrifuge Warranty Related Documents...
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Illustrations Illustrations Home Page, 2-1 Header Bar, 2-2 Home Page Button, 2-2 Menu Button, 2-3 Ready Status, 2-3 Header Bar - Ready Status, 2-3 Header Bar - Running Status, 2-3 Header Bar - Stopping Status, 2-4 Header Bar - Warning Message, 2-4 2.10 Header Bar - Error...
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Illustrations Run History (Filtered View), 4-9 Run History Button, 4-10 Run History Filter, 4-10 Set From Date and Time, 4-11 Run Graph Button, 4-12 Run History Button, 4-12 Run Graph Options, 4-13 Run Graph Button, 4-13 Run History Button, 4-14 4.10 Run History Button, 4-14...
Introduction Overview This introduction contains the following information: • About This Manual Conventions • Certification • Scope of Manual • CFC-Free Centrifugation • Software Copyright • Symbols • Graphics • About This Manual The information in your User’s Manual is organized as follows: CHAPTER 1, Description Describes the Avanti JXN series centrifuge components and their functions.
Certification To ensure full system quality, Beckman Coulter Avanti JXN series have been manufactured in a facility that maintains certifications to both ISO 9001:2008 and ISO 13485:2003. They have been designed and tested to conform to (when used with Beckman Coulter rotors) the laboratory equipment requirements of applicable regulatory agencies.
Further, the use of any equipment other than that recommended by Beckman Coulter has not been evaluated for safety. Use of any equipment not specifically recommended in this manual and/or the appropriate rotor manual is the sole responsibility of the user.
Introduction Graphics Graphics All graphics, including screens and printouts, are for illustration purposes only and must not be used for any other purpose. The graphics that your system generates may differ from what is displayed in this manual. PN B38322AA xxxi...
CHAPTER 1 Description Overview This section describes the Avanti JXN series centrifuge components and their functions. It also describes system safety features and centrifuge controls and displays. Refer to the applicable rotor manual for rotor descriptions. This chapter contains information about: For In Vitro Diagnostic Use •...
Centrifuge Function The Avanti JXN series is a refrigerated centrifuge that generates centrifugal forces required for a wide variety of applications. Together with the Beckman Coulter rotors designed for use in this centrifuge, applications include: • Routine processing such as sample preparations, pelleting, extractions, purifications, concentrations, phase separations, and spin column and spin filter centrifugations.
Description Housing and Door Housing and Door The instrument control housing, door assembly, and cover panels are made from a highly-durable plastic. The door is opened by stepping on a foot pedal, which is located at the bottom right front of the instrument.
Description Overtemp System Overtemp System An overtemp (over temperature) system provides flexibility, sample protection, and safety for the user. • The maximum allowable deviation above the Set Temperature is configured by the user. The default setting is 4°C. • For each run the user sets the desired run temperature. •...
Only values with tolerances or limits are guaranteed data. Values without tolerances are informative data, without guarantee. Table 1.1 Avanti JXN Series Specifications Specifications Description Avanti JXN-26 Avanti JXN-30 Speed Setting range 500 to 26,000 RPM (in 10 500 to 30,000 RPM (in 10...
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Description Specifications Table 1.1 Avanti JXN Series Specifications Specifications Description Avanti JXN-26 Avanti JXN-30 Ventilation Sides 7.6 cm (3 in.) Clearances Rear 16 cm (6.25 in.) Finishes Top surfaces Uncoated plastic Painted plastic Front surfaces Painted plastic Other surfaces Acrylic baking enamal on metal surfaces...
Description Available Rotors Audible Sounds The Avanti JXN series instrument makes an audible sound for the following events: • Boot up • Start of Run • End of Run • Diagnostics/Alert • Door open during Zonal mode • Key Click Sound volume can be regulated through the Set Sound Page, and some sounds can be customized...
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Description Available Rotors Table 1.2 Available Rotors (Continued) Rotor Profile Description JXN-26 JXN-30 JXN-26 JXN-30 Rotor Capacity Manual Number (´ g) (´ g) 18 ´ 10 mL J-TB-002 JA-21 21,000 21,000 50,380 50,380 Fixed Angle, 40° (18 place) = 102 mm 32 ´...
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Description Available Rotors Table 1.2 Available Rotors (Continued) Rotor Profile Description JXN-26 JXN-30 JXN-26 JXN-30 Rotor Capacity Manual Number (´ g) (´ g) JA-14.50 14,000 14,000 35,050 35,050 16 x 50 mL B32164 Fixed Angle, 35° (16 place) rmax = 160 mm 6 ´...
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Description Available Rotors Table 1.2 Available Rotors (Continued) Rotor Profile Description JXN-26 JXN-30 JXN-26 JXN-30 Rotor Capacity Manual Number (´ g) (´ g) 103,860 6 ´ 38.5 mL J-TB-058 JS-24.38 10,000 24,000 18,030 Swinging Bucket (6 place) = 161 mm 6 ´...
CHAPTER 2 The Touch Screen Interface Overview This chapter describes the touch screen interface for the Avanti JXN series. Except for the power switch, all the controls for the instrument are programmed controls that appear on the touch screen. Figure 2.1 Home Page This chapter contains information about: Areas on the Screen •...
The Touch Screen Interface Areas on the Screen Areas on the Screen The items on the screen may change, depending on the state of the instrument. There are three areas where items appear on the screen: • The Header Bar •...
The Touch Screen Interface Areas on the Screen Menu Button Figure 2.4 Menu Button Button displays the Menu page, including the following functions: Menu • Options • Rotor Catalog • About • Zonal Operation • Service Mode The menu options are explained in the following chapters. Status Display Figure 2.5 Ready Status The Status Display is in the middle of the Header Bar and shows you the current instrument status,...
The Touch Screen Interface Areas on the Screen Figure 2.8 Header Bar - Stopping Status • Yellow background: warning message. Figure 2.9 Header Bar - Warning Message • Red background: error message. Figure 2.10 Header Bar - Error Message Help Button Figure 2.11 Help Button button gives you access to the built-in online help messages.
The Touch Screen Interface Areas on the Screen Stop Button Figure 2.13 Stop Button button stops the current run immediately. This is ordinarily only used for emergencies or Stop if you mistakenly set too long a run time. Footer Bar on the Home Page On the Page, the middle of the Footer Bar shows three Items: Home...
The Touch Screen Interface Help Messages System Name The system name displays the system name entered as one of the options on the System Options Page. This section also displays the user currently logged in to the system (if enabled), and the avatar and background (if selected) for that user.
The Touch Screen Interface Help Messages Figure 2.17 Global Help Button attached to Help Button While using Global Help, you also have some additional options: • The page appears over a ghost image of the screen you were on when you selected Global Help global help.
Help About Your Instrument The system About page contains information about your instrument, including the model number, serial number, and software version, that you need when you call your Beckman Coulter Representative. Follow this procedure to display the About Page.
The Touch Screen Interface About Your Instrument Figure 2.22 About Page Displaying the About Page Select the button on the header bar to display the page. Menu Menu Select the button to display the t page. About Abou PN B38322AA...
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The Touch Screen Interface About Your Instrument 2-10 PN B38322AA...
CHAPTER 3 Operations Overview The touch screen interface for the Avanti JXN simplifies operations. Although there are many additional things you can do. This chapter contains information about: Manual Operation • Zonal and Continuous Flow Operation • Manual Operation Manual operation is a simple procedure you can do from the Page.
Operations Manual Operation Set the time. Set the temperature. Start the run. Step 1: Start on the Home Page Start at the Page. If your screen shows any other page, select the Button in the Home Home Page upper left corner of the screen. Figure 3.1 Home Page NOTE If your system is in Zonal Mode, you must select the Cancel Button to go to the Home Page.
Operations Manual Operation Figure 3.2 Zonal Operation Page with Cancel Button Step 2: Set the Speed and Rotor Select the Display/Button on the Page to go to the Page. Set Speed Home Set Speed Figure 3.3 Set Speed Page When the Page appears, follow these steps: Set Speed PN B38322AA...
Operations Manual Operation Setting the Speed and Rotor Select the Button to go to the Page. Select Rotor Select Rotor Figure 3.4 Select Rotor Select the rotor for the run from the library. If the desired rotor is not in the library, a system Administrator or Super User must add it.
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Operations Manual Operation Figure 3.5 Set Acceleration/Deceleration Profiles Page On the Page, follow these steps: Set Acceleration/Deceleration Profiles Setting the Acceleration and Deceleration Profiles Select the desired Acceleration and Deceleration profiles. Select the key to accept your entries and dismiss the page. PN B38322AA...
Operations Manual Operation Step 4: Set the Time Select the Display/Button to go to the Page. Set Time Set Time Figure 3.6 Set Time Page On the Page, follow these steps: Set Time Setting the Time Use the keypad to set the desired time in hours and minutes. Use the keys to Back Clear...
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Operations Manual Operation You can use the button to set a future start or stop time. Select to display Delay Start Delay Start the Delay Start Page. Figure 3.7 Delay Start Page • Select to set a starting or stopping time. Then you can set the date and Start At Stop At time in the fields above.
Operations Manual Operation Step 5: Set the Temperature Select the Display/Button to go to the Page. Set Temp Set Temperature Figure 3.8 Set Temperature Page On the Page, follow two steps: Set Temperature Setting the Temperature Use the keypad to set the desired temperature in degrees Celsius. Use the keys Back Clear...
Operations Zonal and Continuous Flow Operation Mount the rotor in the instrument following all the procedures in the rotor manual and observing all safety procedures and cautions. Close the chamber door. Select the button. Start Figure 3.9 Start Button NOTE When the run begins, wait for the countdown timer to reach zero and the rotor to come to a stop.
Operations Zonal and Continuous Flow Operation Zonal and Continuous Flow operations are very similar. The specific details vary according to the rotor you are using, but the summary below shows an outline of the procedure. Figure 3.10 Zonal Page There are seven phases to a Zonal or Continuous Flow run: •...
Operations Zonal and Continuous Flow Operation For Continuous Flow operation, you may have two different load speed settings. The initial setting is for alignment and adjustment checks, which you set in this phase. When everything else is ready, mount the rotor. Starting the Run To start the run, select the Button and wait for the rotor to reach loading speed.
Operations Zonal and Continuous Flow Operation Running the Sample The instrument highlights Running on the Status Display, accelerates to the set run speed, and begins counting down the set run time. The run phase ends in one of three ways: •...
CHAPTER 4 Configuration Overview The Avanti JXN series includes many options for configuring your system. Some of these options have a significant effect on system functionality, and must be configured before you begin to use the system. This chapter contains information about: Managing Your Network •...
Use this option to select a USB or network printer for the instrument. The system automatically sends all print requests to the selected printer. NOTE Printer drivers must be installed by your Beckman Coulter Representative. Select the Button on the Header Bar to display the page.
Configuration Managing Your Network Select the button on the Header Bar to display the page. Menu Menu Select to display the page. Options System Options Select the Tab, then select to display the page. Network Setup Email Setup Email Select to enter your email server address.
Configuration Managing Users Select to display the page. Options System Options Select the Tab, then select to display the page. Network Setup VNC Setup VNC Select the Enable or Disable VNC Server button to enable the VNC server. The button Enable displays a green square when the option is enabled.
Configuration Managing Users Table 4.1 User Levels User Level Permission Operator Can run assigned programs and change user options. Super User Can run all programs, run the centrifuge manually, manage users, assign programs, and manage the rotor library. Administrator Unlimited access. Adding Users To add users to the system, select the Button on the Header Bar to display the...
Configuration Managing Users Select to display the Page. Options System Options Select the Tab, then select . The button displays a green square when the Users Require Login option is enabled. PIN Expiration and Logout Timer The system defaults to expire PINs every 60 days, and to log out users after two minutes of inactivity.
Configuration Managing Rotors User Options When Login is required, the User Options page becomes active. From this page, users can change their PIN, add or change their email and phone number, and select an avatar and background to appear on their Home page. Changing User Options Select the button on the Header Bar to display the...
Configuration Managing Rotors Adding Rotors To add rotors to the rotor library, select the button on the Header Bar to display the Menu Menu page. Select to display the page. Options System Options Select the Tab, then select to display the page.
Configuration Managing Reports Managing Reports The Avanti JXN series automatically saves run history data associated with each run. The run history generated includes: Figure 4.1 Run History (Filtered View) • User information • Start date and time of the run •...
Configuration Managing Reports Filtering Data You can filter run history data before you graph or print it. On the page, select the button on the side menu. Home Run History Figure 4.2 Run History Button On the page, select the tab at the bottom of the screen.
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Configuration Managing Reports Select the button, then select the button. Filter by Date From Figure 4.4 Set From Date and Time On the page, use the up and down arrow buttons to set the parameters Set From Date and Time for the Month, Day, Year, Hour, Minute, and AM/PM.
Configuration Managing Reports Graphing Data To graph data for a run in progress: Graphing Data for a Run in Progress Select the button on the side menu of the page. Run Graph Home Figure 4.5 Run Graph Button On the page, select Real-Time Run Data Options...
Configuration Managing Reports On the page, choose one of three options: , or Run Graph Options Fit To Screen Auto Scroll Manual is the default.) Then select Scroll Fit To Screen Figure 4.7 Run Graph Options Print Data You can print run history from the Run Graph page or the Run History page. NOTE You must have Administrator access to configure the printer.
Configuration Managing Reports Select the button. The system sends the run graph to the printer configured by the Print Administrator. Printing RunHistory from the Run History Page Select the button from the side menu of the page. Run History Home Figure 4.9 Run History Button Use filtering to display the run histories you want to print.
Configuration Managing Reports On the page, use filtering to display the run histories you want to export, then select Run History button. Export Figure 4.11 Run History On the page, the system displays a prompt to insert the USB drive. Export Run History When the system reads the USB drive, select it from the Available Drives list, and select the button.
Configuration Managing Reports On the page, select the network from the Available Drives list, then select the Export Run History button. Export Auto Print and Auto Export Run History Data A user with Administrator access can configure the Avanti JXN series to automatically print run history data.
Configuration Managing Reports Select the button. Options Select the tab. Reports Select the button. Auto Export The small box in the button will turn green to indicate it is enabled. Auto Export When a run is completed, the instrument automatically exports the run history data to the network (if previously configured) as a .csv file (a simple text spreadsheet) and an .xml file (a simple, structured text format).
Configuration Managing Reports The system displays the page. Enter a comment and select to start the Before Run Comment run. You can leave the comment field blank, but you must select to start the run. If you select , the run will not start. Cancel Figure 4.13 Before Run Comment When the run stops or you select the...
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Configuration Managing Reports To disable the function, follow the previous four steps. E-Signature The small box in the button will turn grey to indicate it is disabled. E-Signature Using E-Signature After a run is complete, select the button on the side menu of the Home page. Run History On the page, select the run to which comments will be added.
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Configuration Managing Reports The note and E-Signature will be added to the Summary on the page. See the Run History Run History Page for more information. 4-20 PN B38322AA...
CHAPTER 5 Programs Overview The Avanti JXN series includes the functionality to create and store programs in the centrifuge memory. A program is a series of steps containing parameters for a run. Programs are retained in the centrifuge memory until they are deleted. This chapter contains information about: Creating Programs •...
Programs Creating Programs Creating Programs Creating Programs Select from the side menu on the page. Program Home NOTE When Require Login is enabled, programs can only be created by an Administrator or Super User. Figure 5.1 Program Button Figure 5.2 Home PN B38322AA...
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Programs Creating Programs On the page, select the button. Select Program Figure 5.3 Select Program On the page, appears as the title. To name the new program now, New Program •Unnamed• select on the screen. •Unnamed• Figure 5.4 Unnamed program PN B38322AA...
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Programs Creating Programs On the page, use the keyboard to name it, then select to save it. New Program Name NOTE Program names cannot be reused. Figure 5.5 New Program Name On the page, select the button to set the Acceleration and Deceleration New Program Accel Decel profiles.
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Programs Creating Programs To specify the rotor, select the button. The system displays rotor types. Select a rotor. Rotor When you are finished making your selection, select to save them and return to the previous page. NOTE Specifying a rotor type is optional. However, if a rotor type is selected within the program editor, this constrains the other program settings and the rotor instance selected for the run.
Programs Running Programs a. Select the button at the top of the page, then use the keypad to set the speed. The Set Speed speed must be at least 500 RPM up to the maximum speed for the selected rotor. If you plan to set the speed in units of relative centrifugal field (RCF), select the button.
Programs Editing Programs Running Programs Select from the side menu on the page. Program Home Figure 5.10 Program Button On the page, choose the program you want to run, then select Select Program NOTE The list will only show the programs that are authorized for use by the user. Select the button.
Programs Deleting Programs Select the program you want to edit and select the button. If the program is selected to run, Edit that selection will be cleared. If the program is running, the button will be disabled. Edit On the page, select the numbered step you want to edit, then select the Edit Program Edit Step...
CHAPTER 6 Functional Pages Overview This chapter describes the functional pages used to control the Avanti JXN series. They include all of the following: Home Page • Home Page (Run in Progress) • • Set Speed Page Select Rotor Page (Library) •...
Functional Pages Overview Select Language Page • User Options Page • Max Temperature Offset Page • Reset User PIN Page • Select Image Page • Set Date and Time Page • System Log Page • Manage Rotors Page • Add to Rotor Library Page •...
Functional Pages Home Page Home Page Figure 6.1 Home Page page is the first operational page to appear after the instrument startup. To display the Home Home page, select the page button on the Header Bar. It is the basic page from which you Home begin most operations.
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Functional Pages Home Page Select the Display/Button to display the Set Time Page (Set Speed ω²t Time Page if the Set Time w²t mode is active). When you are not on the page, the Display/Button appears Home Set Time in the Footer Bar. •...
Functional Pages Home Page (Run in Progress) Home Page (Run in Progress) Figure 6.2 Home Page (Run in Progress) When an actual run is in progress, the page includes the following information: Home • The Display shows the actual speed of the rotor in RPM or RCF. Set Speed •...
Functional Pages Set Speed Page Set Speed Page Figure 6.3 Set Speed Page (Rotor Selected) To set the speed for the next run or change the speed of the run in progress, select the Set Speed Display/Button on the Home Page or the Footer Bar to display the page.
Functional Pages Select Rotor Page (Library) Select Rotor Page (Library) Figure 6.4 Select Rotor Page (Library) To select a rotor for the next run, select the Display/Button on the Home Page or the Rotor Select button on either the Set Speed Page or the Set Speed ω²t Time Page to display the...
Functional Pages Set Time Page Set Time Page Figure 6.5 Set Time Page To set the duration for the next run or change the duration of the run in progress, select the Display/Button on the Home Page or the Footer Bar to display the page.
Functional Pages Delay Start Page Delay Start Page Figure 6.6 Delay Start Page To set a future start or end time for the next run, select the button on the Set Time Page Delay Start or the Set Speed ω²t Time Page to display the page.
Functional Pages Set Speed ω²t Time Page Set Speed ω²t Time Page Figure 6.7 Set Speed ω²t Time Page When the ω²t mode is active and you select either the button or the button on Set Speed Set Time Home Page or the Footer Bar, the system displays the page.
Functional Pages Set Temperature Page Set Temperature Page Figure 6.8 Set Temperature Page To set the temperature for the next run or change the temperature for the run in progress, select button on the Home Page or the Footer Bar to display the Set Temperature Set Temperature page.
Functional Pages Set Acceleration/Deceleration Profiles Page Set Acceleration/Deceleration Profiles Page Figure 6.9 Set Acceleration/Deceleration Profiles Page To choose profiles for acceleration and deceleration, select the Display/Button in the Accel/Decel Footer Bar of the Home Page to display the page. Set Acceleration/Deceleration Profiles In addition to the Header Bar and the Footer Bar, the page Set Acceleration/Deceleration Profiles...
Functional Pages Login Page Example Acceleration and Deceleration Settings The values associated with each acceleration and deceleration setting are given in the table below. Table 6.1 Acceleration and Deceleration Profiles Setting Description Maximum acceleration (not available Full torque is used from 0 RPM until set speed is reached. with the JS-24.38 and JS-24.15 rotors) Timed acceleration Acceleration time from 0 to 500 RPM can be set from 1 to 10...
Functional Pages Select Program Page To enable or disable the user login requirement, select The Users Tab of the System Require Login Options Page. NOTE Only an Administrator can change this setting. • To log in, select your User ID from the list on the left. Use the keypad to enter your PIN on the right, and select Login •...
Functional Pages New/Edit/View Program Page • Select to grant Operator-level users permission to run the selected program. Authorize Users The system displays the Authorize Users Page. • Select the button to discard your changes and dismiss the page. Cancel • Select to print the selected program.
Functional Pages New/Edit/View Program Page Figure 6.14 View Program Page To create a run program, select the button on the Select Program Page to display the page. To edit or view a run program, select the program and select the button Program Edit...
Functional Pages Select Rotor Page (Catalog) Select Rotor Page (Catalog) Figure 6.15 Select Rotor Page (Catalog) To select a type of rotor for a run program, select the button on the New Program Page or the Rotor Edit Program Page to display the page (Catalog).
Functional Pages New/Edit Step Page New/Edit Step Page Figure 6.16 New Step Page Figure 6.17 Edit Step Page To create a step within a run program, select the button on the New Program Page or the New Step Edit Program Page to display the page.
Functional Pages Program Log Page • The field shows the default or the current step Set Time in hours and minutes. Select Set Time the field and use the keypad to change the entry as required. • The field shows the default or current step Set Temperature setting in degrees Set Temp Celsius.
Functional Pages Export Page • Select the button to return to the Select Program Page. Back • Select to print the program log. Print • Select to export the program log. The system displays the Export Page. Export Export Page Figure 6.19 Export Page Different kinds of information can be exported from the Avanti JXN series to a USB device or network drive.
Functional Pages Authorize Users Page Authorize Users Page Figure 6.20 Authorize Users Page To manage the list of users with permission to run a program, select the program and select the button on the Select Program Page to display the page.
Functional Pages Import Page Import Page Figure 6.21 Import Page Many kinds of information can be imported to the Avanti JXN series from a USB device or network drive. All Import pages function in the same manner. NOTE Do not remove a USB drive while a data transfer is in progress. In addition to the Header Bar and the Footer Bar, the page contains the following elements: Import...
Functional Pages Real-Time Run Data/Historical Run Data Page Real-Time Run Data/Historical Run Data Page Figure 6.22 Real-Time Run Data Page Figure 6.23 Historical Run Data Page Select the button on the side menu of the Home Page to display the Run Graph Real-Time Run Data page.
Functional Pages Run Graph Options Page Figure 6.24 Run Graph Button Select a run log from the Run History Page and select the button to display the Graph Historical Run page for the selected run. Data In addition to the Header Bar and the Footer Bar, the Real-Time Run Data page contains the following elements: •...
Functional Pages Run History Page • The button displays the last 10 minutes of the run, with a scroll bar beneath the Manual Scroll run graph to scroll through the entire run. • Select the button to discard your changes and return to the previous page. Cancel •...
Functional Pages Run History Page Figure 6.27 Run History Page (E-Signature Enabled) Select the button on the side menu of the Home Page to display the page. Run History Run History Figure 6.28 Run History Button In addition to the Header Bar and the Footer Bar, the page contains the following Run History elements:...
Functional Pages Run History Filter Page • The button displays the Run History Filter Page. Filter • The button prints all the listed run logs. (Use to narrow the list.) Print Filter • The button displays the Historical Run Data Page for the selected run log.
Functional Pages Before Run/After Run Comment Page Before Run/After Run Comment Page Figure 6.30 Before Run Comment Page If your system has Run Comments enabled (see The Reports Tab), it displays the Before Run page when you start a run, and the page when a run ends.
Functional Pages Menu Page Menu Page Figure 6.31 Menu Page Select the button in the Header Bar to display the page. Use this page to configure or use Menu Menu the Avanti JXN series options. • The button displays the System Options Page.
Functional Pages System Options Page System Options Page Figure 6.32 System Options Page, Basic Tab Select the button in the page to display the page. Use this page to Options Menu System Options configure the system option settings. page is organized into five tabs. If you have user login enabled, many of the System Options options are restricted to Admin-level users.
Functional Pages System Options Page The System Tab Figure 6.33 System Options Page, System Tab • The button displays the page. Enter the system name and Set System Name Set System Name select to return to the page. System Options •...
Setup Email Page. Setup Email • The button displays the Setup VNC Page. Setup VNC • The button enables and disables the Applications Programming Interface for remote Enable API devices. Contact your Beckman Coulter Representative for more information. 6-32 PN B38322AA...
Functional Pages System Options Page The Users Tab Figure 6.35 System Options Page, Users Tab • The button displays the Manage Users Page. Manage Users • The button displays the . Enter the number of days that you PIN Expiration PIN Expiration Page want PINs to remain valid.
Functional Pages System Options Page The Reports Tab Figure 6.36 System Options Page, Reports Tab • The button enables and disables the Signature function for run logs. See E-Signature E-Signature for more information. • The button enables and disables automatic printing of run logs at the completion of Auto Print each run.
Functional Pages Select Language Page Select Language Page Figure 6.37 Select Language Page Select the button on the Basic tab of the System Options Page to display the Select Language Select page. Use this page to choose the language and date, time and number format the Language instrument uses in operations.
Functional Pages User Options Page User Options Page Figure 6.38 User Options Page Select the button on the Basic tab of the System Options Page to display the User Options User page. Use this page to configure personal options and information for your User ID. Options NOTE You can display this page only if Require Login is enabled (see...
Functional Pages Max Temperature Offset Page Max Temperature Offset Page Figure 6.39 Max Temperature Offset Page Select the button on the Basic tab of the System Options Page to display the Max Temperature Offset page. Use this page to set the tolerable deviation above the set temperature Max Temperature Offset during a run.
Functional Pages Reset User PIN Page Reset User PIN Page Figure 6.40 Reset User PIN Page Select the field on the User Options Page to display the page. Use this page to Reset User PIN change the PIN for your User ID. In addition to the Header Bar and the Footer Bar, the page contains the following Reset User PIN...
Functional Pages Select Image Page Select Image Page Figure 6.41 Select Image Page (Avatar) Figure 6.42 Select Image Page (Background) Select the button or the button on the User Options Page to display the Set Avatar Set Background page. Use this page to select or import an avatar or background for your User ID on the Select Image Avanti JXN series.
Functional Pages Set Date and Time Page In addition to the Header Bar and the Footer Bar, the page contains the following Select Image elements: • The Image list shows all the available avatar or background images. • Select to import an image from a network drive or USB device. The system Import Image displays the Import...
Functional Pages System Log Page and PM notation. With some language/country selections, the 12 hour option may be unavailable and the buttons will not be visible. Select Time Format • The button discards your changes and returns to the System Options Page.
Functional Pages Manage Rotors Page Manage Rotors Page Figure 6.45 Manage Rotors Page To add or delete rotors from your rotor library, select the button on the System tab Manage Rotors of the System Options Page to display the page. See Managing Rotors for more Manage Rotors...
Functional Pages Add to Rotor Library Page Add to Rotor Library Page Figure 6.46 Add to Rotor Library Page To add a rotor to your rotor library, select the button on the Manage Rotors Page to display the page. Add to Rotor Library In addition to the Header Bar and the Footer Bar, the page contains the Add to Rotor Library...
Functional Pages Diagnostic History Page Diagnostic History Page Figure 6.47 Diagnostic History Page Select the button on the System tab of the System Options Page to display the Diagnostic History page. Use this page to review and export the details of incidents that caused a Diagnostic History diagnostic message on the instrument (warnings and error messages).
Functional Pages Set Sound Page Set Sound Page Figure 6.48 Set Sound Page Select the button on the System tab of the System Options Page to display the Set Sound Set Sound page. Use this page to set the volume and enable or disable the key click option. In addition to the Header Bar and the Footer Bar, the page contains the following Set Sound...
Functional Pages Custom Sounds Page Custom Sounds Page Figure 6.49 Custom Sounds Page Select the button on the System tab of the System Options Page to display the Custom Sounds page. Use this page to import custom sounds for various system events. See Audible Custom Sounds Sounds...
Functional Pages Archive Data Page Archive Data Page Figure 6.50 Archive Data Page Select the button on the System tab of the System Options Page to display the Archive Data Archive page. Use this page to configure export of different types of system information. Data NOTE Run History and Diagnostic History cannot be imported back into the system.
Functional Pages Setup Network Page Setup Network Page Figure 6.51 Setup Network Page Select the button on Network tab of the System Options Page to display the Setup Network Setup page. Use this page to configure the network connection. Network In addition to the Header Bar and the Footer Bar, the page contains the following Setup Network...
Select Printer elements: • The Printer list shows the configured printers on the network or physically connected to the instrument. Printers must be configured by your Beckman Coulter Representative. Select the printer to use. • You can select to send a test page to the selected printer.
Functional Pages Setup Email Page Setup Email Page Figure 6.53 Setup Email Page Select the button on the Network tab of the System Options Page to display the Setup Email Setup page. Use this page to configure settings for email sent from the instrument. When email is Email configured, the instrument sends diagnostic notifications to all users with email addresses defined in their user profiles.
Functional Pages Setup VNC Page • The button accepts your changes and returns to the System Options Page. Save Setup VNC Page Figure 6.54 Setup VNC Page Select the Setup VNC button on the Network tab of the System Options Page to display the Setup page.
Functional Pages Manage Users Page Manage Users Page Figure 6.55 Manage Users Page To add, delete or edit your users, select the button on the Users tab of the System Options Program Page to display the page. Manage Users In addition to the Header Bar and the Footer Bar, the page contains the following Manage Users elements:...
Functional Pages Add/Edit User Page Add/Edit User Page Figure 6.56 Add User Page To add a user profile to the system, select the button on the Manage Users Page to display the page. Add User To edit an existing user profile, select the User ID and select on the Manage Users Page Edit...
Functional Pages Authorize Programs Page • For Operator-level user profiles, you can select the button to add Authorize Programs permission to run programs to the user profile. The system displays the Authorize Programs Page. • The button discards your changes and returns to the Manage Users Page.
Functional Pages Rotor Catalog Page Rotor Catalog Page Figure 6.58 Rotor Catalog Page Select the button on the Menu Page to display the page. Use this page Rotor Catalog Rotor Catalog to examine the detailed specifications for all the rotors compatible with the Avanti JXN series. In addition to the Header Bar and the Footer Bar, the page contains the following Rotor Catalog...
Functional Pages About Page About Page Figure 6.59 About Page page appears when you select the button on the Home Page. This page presents About About system information about your instrument. In addition to the Header Bar and the Footer Bar, the page contains the following operating About elements:...
Functional Pages Zonal Authorization Page Zonal Authorization Page IMPORTANT Zonal mode is used when the JCF-Z flow/zonal rotor is installed. Figure 6.60 Zonal Authorization Page Select the button on the side menu of the Home Page, or the button on Zonal Mode Zonal Operation Menu Page...
Functional Pages Zonal Operation Page Zonal Operation Page Figure 6.62 Zonal Operation Page Enter the correct authorization code from the Zonal Authorization Page to display the Zonal page and enter Zonal mode. Operation When you use Zonal mode, the page replaces the Home Page until Zonal mode ends.
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Functional Pages Zonal Operation Page • As a display, the shows the current selected rotor. Select the button to Rotor Display/Button display the Select Rotor page. NOTE Only rotors available for use with the Zonal mode will show in the list. •...
Supply List Field Service For any maintenance not covered in this manual, contact your Beckman Coulter Representative for assistance. USA customers can call 1-800-742-2345. For international contacts, see the website at www.beckmancoulter.com or use the contact numbers on the inside front cover of this book.
Maintenance and Troubleshooting Maintenance Performing Instrument Maintenance Inspect the centrifuge chamber for accumulations of sample, dust, or glass particles from broken sample tubes. a. Clean as required (see Cleaning below). Check the air filter on the back panel for obstructions. a.
If the instrument and/or accessories are contaminated with radioactive or pathogenic solutions, follow appropriate decontamination procedures as determined by your laboratory safety officer. Refer to Chemical Resistances (publication IN-175), or contact your Beckman Coulter Representative to ensure that the decontamination method does not damage any part of the instrument (or accessories).
Ethanol is a flammability hazard. Do not use it in or near operating centrifuges. Ethanol (70%) may be used to clean any exterior surface of the centrifuge. While Beckman Coulter has tested ethanol (70%) and found that it does not damage the centrifuge, no guarantee of sterility or disinfection is expressed or implied.
Maintenance and Troubleshooting Checking the Vacuum Pump To remove the air filter, hold the side edges and lift the filter straight up until the bottom edge is above the centrifuge bottom retaining strip. a. Pull the filter out, bottom edge first, and discard it. Install a new filter.
Maintenance and Troubleshooting Diagnostics/User Messages Remove the centrifuge front panel. Accessing the Rotor in Case of Power Failure for instructions. Unscrew the filler cap. Set the cap aside. Add oil (PN 392760) up to the maximum fill line. Pour the oil through a funnel if necessary. Screw the filler cap back on tightly.
Maintenance and Troubleshooting Accessing the Rotor in Case of Power Failure you may need to override the door-locking mechanism manually to remove the rotor and retrieve your sample. To access the door-locking mechanism, you must remove the instrument front panel. Two latches secure the front panel in place;...
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Maintenance and Troubleshooting Accessing the Rotor in Case of Power Failure Lift the front panel up and off the centrifuge; set it aside. • You will see an inner front panel that extends about halfway down from the centrifuge top (see Figure 7.3).
Maintenance and Troubleshooting Accessing the Rotor in Case of Power Failure The vacuum will be completely vented several seconds after the hose is detached. NOTE Several tubing lines are tied to the red hose. As you grasp the hose, place your hand over these lines.
Maintenance and Troubleshooting Accessing the Rotor in Case of Power Failure 1. Red Hose Pull the interlock level out and left, and while holding it out, step on the foot pedal. DANGER Risk of serious injury or death to the operator. Never try to slow or stop the rotor by hand.
To ensure that the instrument does not get damaged, contact your Beckman Coulter Representative for specific instructions and/or assistance in preparing the equipment for transport or long-term storage. * In the United States, call 1-800-742-2345. Outside the U.S., contact your local Beckman Coulter office or visit us at www.beckmancoulter.com. PN B38322AA...
Supply List Supply List Contact Beckman Coulter Sales for assistance ordering parts and supplies. Customers in the United States call 1-800-742-2345. For international contacts, see the website at www.beckmancoulter.com or use the contact numbers on the inside front cover of this book. A partial list of supplies is given below for your convenience.
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Maintenance and Troubleshooting Supply List Table 7.1 Replacement Parts Description Part Number Cable Clamp, nylon, 9.6-mm (3/8-in.) I.D. (qty 10) 000596 External HEPA Filter Assembly B45269 NOTE Accessory HEPA filter Kit B37916 is required. PN B38322AA 7-13...
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Maintenance and Troubleshooting Supply List 7-14 PN B38322AA...
APPENDIX A Preinstallation Requirements Preinstallation Requirements Do not attempt to install this instrument. Its purchase price includes installation by Beckman Coulter personnel. Installation by anyone other than an authorized Beckman Coulter Representative invalidates any warranty covering the instrument. Preinstallation requirements have been sent prior to shipment of the instrument. The following information is provided in case the centrifuge must be relocated.
Preinstallation Requirements Preinstallation Requirements Table A.1 Nominal Supply Voltage Ratings for the Avanti JXN Series Nominal Nominal Supply Power Cord and Plug Description Instrument Frequency Voltage Rating Single-phase, 180–264 V, permanently attached three-wire 200/208/240 V 50/60 Hz, 30 A UL/CSA-approved cord with NEMA type 6-30P plug Single-phase, 180–264 V,...
Preinstallation Requirements Preinstallation Requirements Additional Requirements for Three-Phase Power Connections For three-phase power service to the centrifuge, use the “ ” connected configuration shown in Figure A.3. Also note the following information: • The steady state current draw of the centrifuge can be as high as 12 amperes per phase, depending on the voltage.
Using J2 Series Rotors in the Avanti JXN Series CAUTION Do not use the Beckman Coulter JA-10, JS-7.5, or JA-14 rotors in the Avanti JXN centrifuge before reading this information. Checking for Rotor Drive Pins...
Avanti JXN series. Call your local Beckman Coulter office for information on returning the rotor to the factory for upgrading. * In the United States, call 1-800-742-2345. Outside the U.S., contact your local Beckman Coulter office or visit us at www.beckmancoulter.com. PN B38322AA...
Preinstallation Requirements Using J2 Series Rotors in the Avanti JXN Series Using the JCF-Z Continuous Flow/Zonal Rotor Zonal Bracket Kits A special bracket and mounting hardware are required when the JCF-Z Continuous Flow/Zonal Rotor is used. These parts are contained in the Zonal Bracket Kit. The Zonal Bracket Kit includes a bracket, mounting hardware, and assembly instructions.
APPENDIX B Temperature Calibration Procedure Introduction The Avanti JXN series centrifuge specification for temperature control is ± 2°C. The following procedure is provided for those cases in which temperature control within ± 1°C is required. In this procedure, you will measure the temperature of your sample after equilibrating the rotor temperature for a minimum of 1 hour.
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Temperature Calibration Procedure Introduction If the measured and set temperatures are different, note how many degrees different they are and adjust the set temperature up or down that number of degrees. For example: If the required sample And the measured buffer/ Set the temperature temperature is water temperature is...
CHAPTER 7, Maintenance and Troubleshooting. For any maintenance not covered in this manual, contact your Beckman Coulter Representative for assistance. USA customers can call 1-800-742-2345. For international contacts, see the website at www.beckmancoulter.com or use the contact numbers on the inside front cover of this book.
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Make sure printer is powered on and necessary drivers are installed. If problem persists, contact Printer error your Beckman Coulter Representative. S123/ Notification only Contact your Beckman Coulter Representative. Communications error S124/ Hard drive is 90% full Backup files soon. Hard drive space low Contact your Beckman Coulter Representative.
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Notification only, continue Press STOP, then clear the error Set the new run speed and then press START to begin a new run. Rotor acceleration error If error persists, contact your Beckman Coulter Representative. H5-H6/ Notification only, continue Contact your Beckman Coulter Representative.
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Recommended Action T300/ Set Temperature Clear error automatically adjusted Set temperature error C1, C4/ Notification only, continue If error persists, contact your Beckman Coulter Representative. Temperature control error C2-C3, C5/ Run stops using maximum Contact your Beckman Coulter Representative. brake...
(including but not limited to copyright in and to Beckman Works, any derivative work based on part or all of Beckman Works, and images, photographs, text, and other information that may be incorporated in Beckman Works), are owned and reserved by Beckman Coulter, Inc. A. AdornedControl, available at <http://www.codeproject.com/KB/WPF/adornedcontrol.aspx>, by Ashley Davis, the standard version included in its binary form linked with other modules.
D. VNC® Free Edition 4.1.3, Copyright 2002-2008 RealVNC Limited, is included in its unmodified binary form as aggregate work. A copy of this work in source form may be obtained at no cost by contacting Beckman Coulter Technical Support. This work is made available under the following license:...
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Third Party Contributions and Legal Notices Contributions and Legal Notices guarantee your freedom to share and change all versions of a program--to make sure it remains free software for all its users. We, the Free Software Foundation, use the GNU General Public License for most of our software;...
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Third Party Contributions and Legal Notices Contributions and Legal Notices “The Program” refers to any copyrightable work licensed under this License. Each licensee is addressed as “you”. “Licensees” and “recipients” may be individuals or organizations. To “modify” a work means to copy from or adapt all or part of the work in a fashion requiring copyright permission, other than the making of an exact copy.
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Third Party Contributions and Legal Notices Contributions and Legal Notices The Corresponding Source for a work in source code form is that same work. 2. Basic Permissions All rights granted under this License are granted for the term of copyright on the Program, and are irrevocable provided the stated conditions are met.
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Third Party Contributions and Legal Notices Contributions and Legal Notices additional terms, to the whole of the work and all its parts, regardless of how they are packaged. This License gives no permission to license the work in any other way, but it does not invalidate such permission if you have separately received it.
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Third Party Contributions and Legal Notices Contributions and Legal Notices A “User Product” is either (1) a “consumer product”, which means any tangible personal property which is normally used for personal, family, or household purposes, or (2) anything designed or sold for incorporation into a dwelling.
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Third Party Contributions and Legal Notices Contributions and Legal Notices Notwithstanding any other provisions of this License, for material you add to a covered work, you may (if authorized by the copyright holders of that material) supplement the terms of this License with terms: •...
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Third Party Contributions and Legal Notices Contributions and Legal Notices permanently reinstated, you do not qualify to receive new licenses for the same material under section 10. 9. Acceptance Not Required for Having Copies. Your are not required to accept this License in order to receive or run a copy of the Program. Ancillary propagation of a covered work occurring solely as a consequence of using peer-to-peer transmission to receive a copy likewise does not require acceptance.
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Third Party Contributions and Legal Notices Contributions and Legal Notices requirements of this License, to extend the patent license to downstream recipients. “Knowingly relying” means you have actual knowledge that, but for the patent license, your conveying the covered work in a country, or your recipient’s use of the covered work in a country, would infringe one or more identifiable patents in that country that you have reason to believe are valid.
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Third Party Contributions and Legal Notices Contributions and Legal Notices If the Program specifies that a proxy can decide which future versions of the GNU General Public License can be used, that proxy’s public statement of acceptance of a version permanently authorizes you to choose that version for the Program.
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Third Party Contributions and Legal Notices Contributions and Legal Notices D-12 PN B38322AA...
APPENDIX E HEPA Filter Replacement Instructions for the Avanti JXN Series Centrifuges HEPA Filter Replacement The external HEPA filter is located on the left side of the centrifuge. To replace the filter assembly, remove the tubing from the plastic barbed fitting protruding from the side of the centrifuge. Install the new filter assembly (B45269) ensuring the arrow on the filter is pointing down.
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HEPA Filter Replacement Instructions for the Avanti JXN Series Centrifuges HEPA Filter Replacement PN B38322AA...
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Abbreviations KB — Kilobyte A — Ampere kg — Kilograms ACA — Australian Communication Authority kW — Kilowatt API — Application Programming Interface lb — Pound Btu — British Thermal Unit LCD — Liquid-Crystal Display °C — Degrees Celsius or Degrees Centigrade m —...
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Index Symbols areas on the screen, accel and decel display/button, °C footer bar, defined, Abbreviations-1 footer bar on other pages, °F footer bar on the home page, defined, Abbreviations-1 header bar, help button, home page button, menu button, page display area, defined, Abbreviations-1 start button,...
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Index defined, Abbreviations-1 centrifugation editing function, programs, certification, -xxviii EFUP defined, Abbreviations-1 defined, Abbreviations-1 electrical CFC-free centrifugation, -xxix preinstallation requirements, changing email defaults for logout timer, setup, defaults for PIN expiration, emergency door release latch access, changing user options, enable checking for rotor drive pins, e-signature, 4-18...
Index graphics, -xxxi graphics disclaimer, xxxi JCF-Z graphing rotor identification, 7-11 data for a previously completed run, 4-12 JCF-Z continuous flow/zonal rotor data for a run in progress, 4-12 using, graphing data, 4-12 header bar defined, Abbreviations-1 error message, ready status, defined, Abbreviations-1 running status,...
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Any product claimed to be defective must, if requested by Beckman Coulter, be returned to the factory, transportation charges prepaid, and will be returned to Buyer with the transportation charges collect unless the product is found to be defective, in which case Beckman Coulter will pay all transportation charges.
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Beckman Coulter, Inc. Avanti JXN Series Centrifuge Warranty Warranty-2 PN B38322AA...
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