Flags; Morphology Flags; Summary - Siemens ADVIA 2120 Operator's Manual

Morphology Flags

Summary

Laboratory personnel are alerted to suspected sample abnormalities through the
combined use of morphology and quantitative flags (high and low). ADVIA
2120/2120i morphology flags are derived from a series of complex algorithms.
These algorithms are based on the identification of conditions surrounding the
presence of abnormalities.
For a description of result rounding, please see Calculation of Results in the
Regulatory Information Section of this manual.
The ADVIA 2120/2120i system does not enumerate abnormal cells. Despite a
high degree of sensitivity and specificity in detecting conditions consistent with
the presence of abnormal cells, test results produced by the ADVIA 2120/2120i
system are intended for laboratory use only. Whenever morphology or
quantitative flags are triggered, the laboratory, before reporting patient results,
must validate the results and take the appropriate action in accordance with
established standard operating procedures.
Morphology flags appear on the Run Screen and the Review / Edit tab.
The following table identifies the morphology flags and that can be triggered for
each test selectivity. The two-letter codes in parentheses appear on the Run
Screen.
Flag Triggering Criteria
ANISO RDW ≥
ATYP %LUC
%LUC
BLASTS 1. %BLASTS 1.5% to
5.0% and %LUC ≥ 4.5%
or
2. %BLASTS > 5.0%
WBCB or
3. %BASO + %BASO
Susp + %BASO Sat ≥
10%
HDW ≥ 3.4 g/dL
HCVAR
HYPER %HYPER ≥ 4%
%HYPO ≥ 4%
HYPO
IG [(%NEUT + %EOS) -
%PMN]

Flags

16%
≥ 4.5 and
≥
(%BLAST + 1.5)
≥ 5.0%
CBC CBC / CBC / DIFF
DIFF / RETIC
CBC / RETIC
RETIC
6-3