Poor Vacuum Without Reagent Gas Flow; High Pressure With Reagent Gas Flow - Agilent Technologies 7250 Troubleshooting And Maintenance Manual

3 CI Troubleshooting

Poor vacuum without reagent gas flow

Excess water
Allow the instrument to bake out more and flow reagent gas through the lines to
purge any accumulated water.
Air leak
Run an air and water check. See the software online help for additional
information.
The foreline pump is not working properly
For the standard foreline pump, replace the pump oil. If that does not help,
contact your local Agilent Technologies service representative.
The turbo pumps are not working properly
Check the pump speed. It should be at least 95%. Contact your local Agilent
Technologies service representative.
Use of ammonia as reagent gas can shorten the life of the foreline pump oil
C AU T I O N
(with standard pump) and possibly of the foreline pump itself. See
Minimize Rotary Vane Foreline Pump Damage from Ammonia"

High pressure with reagent gas flow

The reagent gas flow rate is too high
On the flow controller, turn down reagent gas flow as appropriate. Verify that
reagent ion ratios are correct.
Air leak
Run an air and water check. See the software online help for additional
information.
Interface tip seal is not installed
Check the source storage box. If the seal is not in the box, vent the MS and verify
that the seal is correctly installed.
56 7250 Accurate-Mass Q-TOF Troubleshooting and Maintenance Manual
"To
on page 86.