Agilent Technologies 1290 Infinity LC System System Manual And Quick Reference page 24

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The Agilent 1290 Infinity LC System - Product Description
New Features of the Agilent 1290 Infinity LC System
The pressure range offers the ability to work with the latest sub-two micron
particles in long columns for high resolution and short columns for fast
separation at increased flow rates. The flow rate range allows not only
traditional methods to be used but also superficially porous (or pellicular)
packing materials (for example, Poroshell) at high flow rates. These types of
packing have recently gained new interest as an alternative approach to STM
materials for high efficiency separations. The flow rate range allows the most
suitable diameter column to be chosen for the separation whether it is 2 mm
for low flow applications such as required by some MS systems or up to 5 mm
id (typically 4.6 mm) for more traditional LC or increased loadability. The flow
rate range also supports the latest research findings that show the benefit of
using maximum flow rates to increase efficiency in gradient separations.
(Refer to Petersson et al., J.Sep.Sci, 31, 2346-2357, 2008, Maximizing peak
capacity and separation speed in liquid chromatography).
The new diode-array detector offers new levels of sensitivity combined with
outstanding baseline characteristics and ease of use due to an innovative cell
design.
The autosampler offers the well-established Agilent flow-through design for
variable volume injection with low carryover upgraded for higher pressure,
lower volume applications. A completely new module, the Flexible Cube, can
be added on to the autosampler to offer fixed loop injection for the absolute
lowest delay volume and other performance enhancements such as needle seat
backflushing.
24 Agilent 1290 Infinity LC System Manual and Quick Reference