Perform System Cip - GE AKTA avant User Manual

7.6.2

Perform System CIP

Introduction
The System CIP method is used to fill the instrument and the selected inlets and outlets
with cleaning solution.
Tip:
Maintenance interval
Perform a System cleaning in place (System CIP) when required, for example between
runs where different samples and buffers are used. This is important to prevent cross-
contamination and bacterial growth in the instrument.
Required material
The following materials are required:
•
•
ÄKTA avant User Manual 29035184 AE
WARNING
If hazardous chemicals are used for system or column cleaning, wash the
system or columns with a neutral solution in the last phase or step.
Appropriate cleaning solutions (e.g., 1 M NaOH, buffer solution or distilled water).
Syringe, 25 ml
Hazardous substances. When using hazardous chemicals,
take all suitable protective measures, such as wearing pro-
tective clothing, glasses and gloves resistant to the sub-
stances used. Follow local and/or national regulations for
safe operation and maintenance of the product.
Hazardous chemicals during run. When using hazardous
chemicals, run System CIP and Column CIP to flush the
entire system tubing with distilled water, before service and
maintenance.
7 Maintenance
7.6 Maintenance when required

7.6.2 Perform System CIP

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