GE AKTApure Manuals

Manuals and User Guides for GE AKTApure. We have 3 GE AKTApure manuals available for free PDF download: User Manual, Operating Instructions Manual

GE AKTApure User Manual

GE AKTApure User Manual (522 pages)

Brand: GE | Category: Laboratory Equipment | Size: 8.25 MB

Table of Contents

Table of Contents
3
1 Introduction

7
2 The ÄKTA Pure Instrument

14
- Overview Illustrations
  15
- Liquid Flow Path
  26
- Instrument Control Panel
  28
- Instrument Modules
  33
  - System Pumps
    34
  - Mixer
    38
  - Valves, Overview
    39
  - Inlet Valves
    40
  - Mixer Valve
    47
  - Injection Valve
    50
  - Loop Valve
    53
  - Column Valves
    56
  - Versatile Valve
    60
  - Ph Valve
    61
  - Outlet Valves
    65
  - Pressure Monitors
    68
  - UV Monitors
    70
  - Conductivity Monitor
    73
  - Flow Restrictor
    75
- Installation of Internal Modules
  77
- Accessories
  80
3 ÄKTA Pure External Modules

87
- External Air Sensors
  88
- Fraction Collector F9-C
  90
- Fraction Collector F9-R
  104
- Sample Pump S9 and S9H
  108
- I/O-Box E9
  112
  - Overview of the I/O-Box
    113
  - I/O-Box E9
    113
  - Analog Connector and Signals
    115
  - Digital Connector and Signals
    117
  - Connect External Equipment to the I/O-Box
    119
- Connection of External Modules
  122
4 System Configuration

124
- Configuration Overview
  125
- Configure Modules
  131
  - Configuration of Inlet Valves
    132
  - Configuration of Mixer Valves
    133
  - Configuration of Loop Valves
    134
  - Configuration of Column Valves
    135
  - Configuration of Versatile Valves
    137
  - Configuration of Ph Valves
    138
  - Configuration of Outlet Valves
    139
  - Configuration of UV Monitors
    140
  - Configuration of Conductivity Monitor
    141
  - Configuration of External Air Sensors
    142
  - Configuration of Fraction Collectors
    143
  - Configuration of I/O-Box
    145
- General System Settings
  146
5 Operation

149
- Before You Prepare the System
  150
- Prepare the Flow Path
  151
- Start UNICORN and Connect to System
  158
- Prime Inlets and Purge Pump Heads
  161
  - System Pumps
    162
  - Sample Pump
    168
- Connect a Column
  173
- Pressure Alarms
  177
- Sample Application
  180
- Fractionation
  193
  - Prepare Fraction Collector F9-C
    194
  - Prepare Fraction Collector F9-R
    200
  - Fractionation Overview
    207
- Create a Method and Perform a Run
  211
  - Create a Method
    212
  - Prepare and Perform a Run
    217
  - Monitor a Run
    219
  - After Run Procedures
    221
6 Performance Tests

225
- General Performance Test Actions
  226
- Air Sensor a and Inlet Valve a Tests
  229
- Air Sensor B and Inlet Valve B Tests
  231
- Air Sensor S and Sample Inlet Valve Tests
  233
- Column Valve C Tests
  235
- Fraction Collector F9-C Test
  237
- Fraction Collector F9-R Test
  240
- Sample Pump Tests
  242
- System Test UV U9-L (Fixed)
  244
- System Test UV U9-M (Variable)
  248
7 Maintenance

252
- Maintenance Manager
  253
- Maintenance Program
  258
- Weekly Maintenance
  261
- Monthly Maintenance
  269
- Semiannual Maintenance
  272
  - Clean the UV Flow Cell
    273
  - Replace the Ph Electrode
    275
- Maintenance When Required
  276
  - Clean the Instrument Externally
    277
  - Perform System CIP
    278
  - Perform Column CIP
    284
  - Clean Fraction Collector F9-C
    288
  - Clean Fraction Collector F9-R
    290
  - Clean Fraction Collector
    290
  - Storage of the Ph Electrode
    291
  - Clean the Ph Electrode
    293
  - Clean the Pump Head Check Valves
    296
  - Wipe off Excess Oil from the Pump Head
    299
  - Clean the Conductivity Flow Cell
    300
- Calibration Procedures
  302
  - Calibrate the Ph Monitor
    303
  - Calibrate the Pressure Monitors
    305
  - Calibrate the Conductivity Monitor
    308
  - Calibrate the UV Monitors
    312
- Replacement Procedures
  316
  - Replace Tubing and Connectors
    317
  - Replace Internal Tubing in Fraction Collector F9-C
    319
  - Replace the Mixer
    322
  - Replace the O-Ring Inside the Mixer
    323
  - Replace the UV Monitor U9-M Flow Cell
    325
  - Replace the UV Monitor U9-L Flow Cell
    328
  - Replace Flow Restrictor
    330
  - Replace the Inlet Filters
    331
  - Replace the Pump Head Check Valves
    332
  - Replace Pump Piston Seals of Pump P9 or P9H
    335
  - Replace Pump Piston Seals of Pump P9-S
    344
  - Replace Pump Pistons
    351
  - Replace Pump Rinsing System Tubing
    352
8 Troubleshooting

355
- Introduction to Troubleshooting
  356
- Troubleshooting: General Checklist
  358
- Troubleshooting: Monitors
  360
- Troubleshooting: Valves
  375
- Troubleshooting: Fraction Collector
  377
- Troubleshooting: Pumps
  387
- Troubleshooting: Other Components
  394
- Troubleshooting: Instrument Communication
  401
- Troubleshooting: Method Development
  403
- Error Codes
  404
9 Reference Information

410
- System Specifications
  411
- Module Specifications
  413
- Tubing and Connectors
  420
- Recommended Tubing Kits for Prepacked Columns
  428
- Chemical Resistance Guide
  431
  - General Information about Biocompatibility and Chemical Resistance
    432
  - Chemical Resistance Specifications
    433
- Wetted Materials
  436
- Predefined Methods and Phases
  438
  - Predefined Purification Methods
    439
  - Predefined Maintenance Methods
    445
  - Predefined Phases
    447
- System Settings
  449
  - System Settings - UV
    450
  - System Settings - Conductivity
    451
  - System Settings - Ph
    452
  - System Settings - Pressure Alarms
    453
  - System Settings - Air Sensor
    455
  - System Settings - I/O-Box
    457
  - System Settings - Fraction Collection
    458
  - System Settings - Tubing and Delay Volumes
    460
  - System Settings - Wash Settings
    462
  - System Settings - Watch Parameters
    463
  - System Settings - Advanced
    464
  - System Settings - Data Collection
    465
- Manual Instructions
  466
  - Manual Instructions - Pumps
    467
  - Manual Instructions - Flow Path
    471
  - Manual Instructions - Monitors
    473
  - Manual Instructions - Fraction Collection
    474
  - Manual Instructions - I/O-Box
    478
  - Manual Instructions - Alarms
    479
  - Manual Instructions - Wash Settings
    482
  - Manual Instructions - Watch Parameters
    483
  - Manual Instructions - Advanced
    484
  - Manual Instructions - Other
    487
- Available Run Data
  488
- Available Curves
  491
- Injection Volumes and Peak Broadening
  493
- Delay Volumes
  494
- Component Volumes
  499
- Pressure Control
  501
- Node Ids
  503
10 Ordering Information

506
Index

514

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GE AKTApure Operating Instructions Manual

GE AKTApure Operating Instructions Manual (160 pages)

Brand: GE | Category: Laboratory Equipment | Size: 2.52 MB

Table of Contents

Table of Contents
2
1 Introduction

4
- About this Manual
  5
- Important User Information
  6
- Regulatory Information
  8
  - EU Directives
    9
  - Eurasian Customs Union
    10
  - Regulations for USA and Canada
    11
  - Other Regulations and Standards
    12
- Associated Documentation
  14
2 Safety Instructions

17
- Safety Precautions
  18
- Labels
  28
- Emergency Procedures
  31
- Recycling Information
  35
- Declaration of Hazardous Substances (Dohs)
  36
3 System Description

38
- ÄKTA Pure Instrument Overview
  39
- UNICORN Software
  50
  - UNICORN Software Overview
    51
  - The System Control Module
    53
4 Installation

55
- Site Preparation
  56
  - Delivery and Storage
    57
  - Room Requirements
    59
  - Site Environment
    62
  - Power Requirements
    64
  - Computer Requirements
    65
  - Required Materials
    67
- Hardware Installation
  68
- Software Installation
  87
- Start UNICORN and Connect to System
  88
- Prime Inlets and Purge Pump Heads
  91
- Performance Test
  99
- Activate Power-Save
  100
5 Prepare the System for a Run

101
- Before You Prepare the System
  103
- Prepare the Flow Path
  104
- Valves and Ports
  107
- Outlet Valve
  107
- Prime Inlets and Purge Pump Heads
  108
- Connect a Column
  109
- Pressure Alarms
  114
- Prepare for a Run at Cold Room Temperature
  117
6 Run a Method

118
- Before You Start
  119
- Applying the Sample
  122
- Start a Method Run
  125
- Monitor the Run
  127
- After Run Procedures
  128
7 Maintenance

132
8 Reference Information

135
- System Specifications
  136
- Chemical Resistance Guide
  139
  - General Information about Biocompatibility and Chemical Resistance
    140
  - Chemical Resistance Specifications
    142
- Ordering Information
  146
- UV Monitor
  148
- Fraction Collector
  149
- Inlet Valve
  150
- Column Valve
  150
- Injection Valve
  151
- Conductivity Monitor
  152
- Flow Restrictor
  153
- Health and Safety Declaration Form
  155
Index

157

GE AKTApure Operating Instructions Manual

GE AKTApure Operating Instructions Manual (142 pages)

Brand: GE | Category: Laboratory Equipment | Size: 4.5 MB

Table of Contents

Table of Contents
3
1 Introduction

5
- See Page
  5
- About this Manual
  6
- Important User Information
  7
- Regulatory Information
  9
2 Safety Instructions

12
- Safety Precautions
  13
- Labels
  23
- Emergency Procedures
  26
- Recycling Information
  29
- Declaration of Hazardous Substances (Dohs)
  30
3 The Instrument and Software

32
- ÄKTA Pure Instrument Overview
  33
- UNICORN Software
  44
  - UNICORN Software Overview
    45
  - System Control Module
    46
4 Installation

49
- Site Preparation
  50
  - Section See Page
    50
  - Delivery and Storage
    51
  - Room Requirements
    53
  - Site Environment
    56
  - Power Requirements
    58
- Hardware Installation
  60
- Software Installation
  78
- Start UNICORN and Connect to System
  79
- Prime Inlets and Purge Pump Heads
  82
- Performance Test
  90
- Activate Power-Save
  91
5 Prepare the System for a Run

92
- Before You Prepare the System
  94
- Prepare the Flow Path
  95
- Prime Inlets and Purge Pump Heads
  99
- Connect a Column
  100
- Pressure Alarms
  105
- Prepare for a Run at Cold Room Temperature
  108
6 Run a Method

109
- Before You Start
  110
- Applying the Sample
  113
- Start a Method Run
  116
- Monitor the Run
  118
- After Run Procedures
  119
7 Maintenance

123
8 Reference Information

126
- System Specifications
  127
- Chemical Resistance Guide
  130
- Check/Change the Node ID of a Module
  135
Index

138

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