GE AKTA avant Operating Instructions Manual page 185

Chemical
Acetonitrile/water/Trifluo-
roacetic acid (TFA)
Ethanol
Isopropanol
Methanol
Water/organic mobile
phase/formic acid
1
2
Note:
Salts and additives for
hydrophobic interaction
chromatography (HIC)
The following chemicals are suitable for continuous use.
Chemical
Ammonium chloride
Ammonium sulfate
Ethylene glycol
Glycerol
ÄKTA avant Operating Instructions 29101556 AB
2
Organic solvents can penetrate weaknesses in PEEK tubing walls more easily than water based
buffers. Special care should therefore be taken with prolonged use of organic solvents close
to pressure limits.
Note: Quaternary valve is not resistant.
Depending on pressure, tubing between pump head and pressure monitor needs to be changed.
See ÄKTA avant User Manual for more information.
Mobile phase system.
It is recommended to replace the mixer sealing ring with the highly resistant
O-ring (product code 29-0113-26) if the system is to be exposed to organic
solvents or high concentrations of organic acids, such as acetic acid and formic
acid, for a longer period of time.
8.2.2 Chemical resistance specifications
Concentra- CAS no/EC no
tion
Max 0.2% N/A
TFA
100% 75-08-1/ 200-837-3
100% 67-63-0/ 200-661-7
100% 74-93-1/ 200-659-6
Max 5% N/A
formic acid
Concentra- CAS no/EC no
tion
2 M 12125-02-9/ 235-186-4
3 M 7783-20-2/ 231-984-1
50% 107-21-1/ 203-473-3
50% 56-81-5/ 200-289-5
8 Reference Information
8.2 Chemical resistance guide
185