Shimadzu IonFocus Instruction Manual page 13

• Select an HPLC compliant or HPLC compatible mobile phase and remove any
fine particles and contaminants by using the filter (part No.: S228-45707-91)
before use.
• Whenever possible, avoid using mobile phases that contain halogen ions, such
as KCl, NaCl and NH
Halogen ions can corrode the stainless steel material (SUS316L) used in
plumbing. If such mobile phases must be used, clean all flow lines thoroughly
with distilled water immediately after analysis.
• A less volatile buffer solution (such as phosphate buffer solution) will cause
precipitation at the interface area, which will decrease sensitivity. Avoid less
volatile buffer solutions.
• Trifluoroacetic acid (TFA) and ion pair reagent, which tend to remain in the
instrument, may affect other analyses.
• Always degas the mobile phase, as air bubbles may tend to form during solvent
mixing or during temperature or pressure changes. Air bubbles may cause
pump malfunctions and detector signal noise.
• For information on the characteristics of the mobile phase to be used, such as
its boiling point or viscosity, refer to the "Mobile Phase Characteristics" section
in the relevant instruction manual of the high performance liquid
chromatograph system you are using.
• Mobile phase solvents must be used in a pH range of 2 to 10. If a mobile
phase solvent is used at high or low pH, corrosion may occur on the aluminum
surface. If corrosion on the aluminum surface is observed, wipe the surface
clean. If necessary, polish the surface with lapping film.
• Discoloration due to corrosion will not affect the performance of the system.
Cl, or that generate halogen ions in certain reactions.
4
Safety Instructions
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IonFocus Unit