Leica CM1520 Instructions For Use Manual page 55

Cryostat
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Disinfection
• At room temperature, wipe contaminated surfaces with a paper towel moistened with alcohol-based
disinfectants.
Warning
Also observe the warning messages in (→ P. 66 – 9. Cleaning, Disinfection, Maintenance).
Trimming the specimen
Warning
• Take care when handling microtome knives and disposable blades. The cutting edge is extremely
sharp and can cause serious injuries! For that reason, always wear the cut-resistant safety gloves
included in the standard scope of delivery!
• Always clamp the specimen BEFORE clamping the knife or the blade.
• Lock the handwheel and cover the knife edge with the safety guard prior to any manipulation of
knife/blade or specimen, prior to changing the specimen block and during all work breaks!
1. Insert the pre-cooled knife/disposable blade into the knife/blade holder.
2. Adjust the knife holder to an appropriate clearance angle. Settings from 4° - 6° (knife holder
CN) and 2° - 5° (blade holder CE, CE-TC and premium blade holder) are suitable for most
applications.
3. Align the knife/knife holder or blade/blade holder with the specimen.
4. Move the safety guard (knife holder CN) to the side or fold the glass anti-roll guide (blade holder
CE, CE-TC and premium blade holder) over to the side.
5. Unlock the handwheel.
6. To trim the specimen, move the specimen towards the knife using the coarse feed buttons. Trim
the specimen down to the required sectioning plane by turning the handwheel
(→ P. 34 – 6.2.6 Setting the section thickness).
7. For section removal, fold the anti-roll guide on the knife and align it with the blade edge.
8. Readjust the anti-roll guide if necessary
the blade holders and
Leica CM1520
(→ P. 46 – Adjusting the anti-roll guide system)
(→ P. 51 – Clearance angle adjustment)
Daily Use of the Instrument
the knife holders.
7
for
55

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