System Components - Waters ACQUITY UPLC H-Class Series System Manual

1.2.1.4 No-Flow Shutdown
The No-Flow Shutdown feature runs the Wash Plungers function after the solvent manager
remains idle for a specified time interval. This feature prevents deposition of precipitated material
on the pump plungers and plunger seals while the system is idle.
1.2.1.5 Automatic Prime
When you enable the solvent manager's Automatic Prime function, the system primes the lines of
the optional solvent selection valve when a new line is selected. You can specify the flow rate and
duration of the prime for the new solvent line.
Example:
If a first injection uses line D1 and a second injection uses line D2, the solvent
manager primes line D2 between the first and second injections.
1.2.1.6 Flow Ramping
Using the Flow Ramping function, you specify the rate at which the solvent manager increases or
decreases flow.
Tip:
The default value is set to support rigid, HPLC and UPLC column particles. For pressure
sensitive columns (such as gel columns), the flow ramping should be adjusted.
1.2.1.7 Auto•Blend Plus
Auto•Blend Plus technology uses pure solvents and concentrated stocks to blend mobile phase
compositions at a specific pH. At the same time, it controls the concentration of salt or organic
solvent, to optimize separations. Use the Auto•Blend Plus feature to create and store buffer
systems in a solvent catalog that all users of an ACQUITY quaternary solvent manager can
share. To prepare and adjust chromatographic mobile phases, you add acid, base, salt, organic
solvent, or water to the solvent reservoirs. By doing so you can, for example, optimize protein
separations, which are especially sensitive to a buffer's pH and salt concentration. You can also
optimize reversed-phase separations that are sensitive to pH and organic-solvent composition.
See also:
• Auto•Blend Plus Technology for Ion Exchange, Size Exclusion, and Reversed-phase
Chromatography, included on the system documentation media.
• The Auto•Blend Plus videos on the Support tab on the

1.3 System components

The following illustration depicts a system stack which includes four core modules and the solvent
bottle tray.
April 4, 2018, 715005702 Rev. A
Page 17
Waters Auto•Blend Plus page.