Switching From Apci To Esi - Thermo Scientific Surveyor MSQ Plus Hardware Manual

Switching From APCI to ESI

Thermo Scientific
Figure 33. View of the corona pin in the operational position for the APCI mode
To switch from the APCI mode to the ESI mode
CAUTION Allow the probe heater to cool before you remove the APCI probe.
1. Turn off the LC pump flow. If you are using the cone wash pump, turn it off.
2. Turn the nitrogen gas, ion optics, and probe heater off by doing one of the following:
• From the Info view - Status page in Xcalibur, right-click the Surveyor MSQ listing to
display a shortcut menu. Then, choose Turn Device Off from the menu.
• Open the Per Method Parameters table in the Tune window. Take the system out of
the Operate mode by clicking the Operate On/Off toggle button, and then turn off
the nitrogen gas by clicking the Nitrogen Gas On/Off toggle button.
3. Allow the probe heater to cool.
4. Unscrew and remove the PEEK fingertight fitting from the APCI probe.
5. Turn the corona pin knob 90 degrees to its vertical position.
6. Turn the locking plate of the APCI probe clockwise to the open position and remove the
APCI probe from the MS detector.
7. Remove the ESI probe from the holder located in the door of the Surveyor MSQ Plus MS
detector and replace it with the APCI probe.
CAUTION Take care not to damage the capillary of the probe as you insert the ESI
probe into the probe heater.
4
Switching Probes
Switching From APCI to ESI
Surveyor MSQ Plus Hardware Manual 53