Cleaning - GE AKTAprime plus Operating Instructions Manual

5 Maintenance
5.2 User maintenance schedule
Interval
Yearly
5.3

Cleaning

Cleaning before planned
maintenance/service
To ensure the protection and safety of service personnel, all equipment and work areas
must be clean and free of any hazardous contaminants before a Service Engineer starts
maintenance work.
Please complete the checklist in the On Site Service Health & Safety Declaration Form or
the Health & Safety Declaration Form for Product Return or Servicing, depending on
whether the instrument is going to be serviced on site or returned for service, respectively.
Copy the form you need from Section 7.4 Health and Safety Declaration Form, on page 62
or print it from the PDF file available on the User Documentation CD.
Cleaning-In-Place
All components in the system are designed for ease of CIP.
After repeated separation cycles, contaminating material might progressively build up
in the system and on the column. This material may not have been removed by the
cleaning step described above. The nature and degree of contamination depends on
the sample and the chromatographic conditions employed. These should be considered
when designing a cleaning protocol.
Routine cleaning should be performed at intervals aimed at prevention rather than
cleaning the system from growth or contamination.
46
Action
Valve inspection
WARNING
Make sure that the piping system is completely leakage free before
performing any CIP on the system.
Instructions/reference
Check for external or internal leakage. Replace
channel plate and distribution plate yearly or
when required. Refer to the relevant valve in-
struction sheet.
ÄKTAprime plus Operating Instructions 28-9597-89 AB