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You can select several types of columns for the nanoACQUITY system.
Analytical columns can have an I.D. of 75 to 300 µm and a length of 10 to
•
25 cm. A nanoACQUITY BEH C18 column has particles of 1.7 µm.
Alternative particle sizes are available with Symmetry
(3.5 µm) or Atlantis
The nanoACQUITY UPLC trap column is 180 µm I.D. × 2 cm long with
•
Symmetry C18, 5 µm particles.
An ion exchange column of 180 µm I.D. × 2.4 cm length with SCX
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material can be used in online 2D-LC techniques.
TUV optical detector
The optional TUV (tunable ultraviolet) optical detector can be used as the
system's sole detector or in conjunction with a mass spectrometer. A
two-channel, ultraviolet/visible (UV/Vis) absorbance detector, the TUV
detector operates from 190 to 700 nm. Its light-guiding flow cell is intended for
high sensitivity chromatography with high peak capacity. The detector,
controlled by MassLynx software for LC/MS applications, operates as an
integral part of the system.
Mass detectors
The nanoACQUITY UPLC™ system acts as a mass spectrometry inlet for
nanoflow rate applications such as proteomics. When coupled with a mass
spectrometer, the system provides sensitive, robust, and reproducible LC/MS
and LC/MS/MS analyses. The system can be configured with an optional
Q-Tof Premier or LCT Premier mass detector.
Q-Tof Premier™
The Waters Q-Tof Premier mass spectrometer is an exact-mass API/MALDI
MS/MS platform for the pharmaceutical, biotechnology, and life science
industries. Designed in conjunction with the nanoACQUITY UPLC system,
the Q-Tof Premier quantifies, identifies, and characterizes compounds from
simple or complex mixtures.
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System Overview
®
dC18 columns (3.0 µm).
®
C18 columns
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