Agilent Technologies SD-1 User Manual page 67

Detection Symptoms
Noisy baseline
Table 16
Probable cause
Air bubbles through flow cell
Leak in system plumbing
Contaminated flow cell
Detector lamp failing
Bad grounding
Electronic interference
Localized temperature effects
SD-1 Solvent Delivery - User Manual
Noisy baseline
Troubleshooting and Diagnostics
Troubleshooting Guide
Suggested actions
• Install backpressure regulator
• Divert flow to waste and pump at a
moderately high flow rate to prime pump
• Check tubing fittings
• Degas solvent
Check for deposits around fittings and check
that all fittings are tight.
Attach a syringe to the flow cell inlet and try to
clear blockage by drawing on the syringe. Or
attach to outlet and back-flush to clear blockage
by gentle pressure on the syringe. Do not apply
pressure to the flow cell inlet.
Check and replace if necessary.
Check all grounding connections on pump and
ensure grounded AC power is supplied to all
devices in HPLC system.
• Check for loose connections
• Ensure instruments are not in direct contact
with each other or with vibrating parts
• Wrap tubing, column
• Remove or cover heat or cooling source
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