Introduction To The Elsd - Agilent Technologies InfinityLab 1290 Infinity II User Manual

1 Introduction to the Detector

Introduction to the ELSD

Introduction to the ELSD

The Evaporative Light Scattering Detector is a unique and highly sensitive
detector for semi-volatile and non-volatile solutes in a liquid stream. It is mainly
used as a concentration detector for High Performance Liquid Chromatography
(HPLC). The solvent stream containing the solute material is nebulized and
carried by a gas flow through an evaporation chamber. The solvent is volatilized,
leaving a mist of solute particles that scatter light to a photosensitive device. The
signal is amplified and a voltage output provides the concentration of the solute
particles passing through the light.
The Agilent 1260 Infinity II ELSD or Agilent 1290 Infinity II ELSD may be used
alone, or as one of several detectors in a GPC or HPLC system. As the solvent or
eluent is evaporated during the analysis, the Agilent 1260 Infinity II ELSD or
Agilent 1290 Infinity II ELSD must be the last in series if used with other
detectors. If the Agilent 1260 Infinity II ELSD or Agilent 1290 Infinity II ELSD is
being used as the last detector in a series, care must be taken not to exceed the
recommended backpressure in detector cells in other units.
This manual instructs the user in the installation and operation of the Agilent
1260 Infinity II ELSD or Agilent 1290 Infinity II ELSD for standalone use and
control using Agilent OpenLab CDS, OpenLab ChemStation, or OpenLab
EZChrom.
Agilent InfinityLab ELSD User Manual 8