MACROMEDIA FREEHAND 10-USING FREEHAND Use Manual page 302

Differences between onscreen colors and those in the final output are inherent.
Monitors display colors using additive RGB color, while printing presses re-create
colors using subtractive CMYK color. Because the RGB gamut, or range of colors,
is much larger than the CMYK gamut, some colors displayed on a monitor can
only be approximated in print.
Illustrations typically pass through one or more electronic devices or software
applications on the way to final output. Printing a FreeHand document to a local
printer, for example, involves FreeHand, your computer's monitor and operating
system, and the printer. Color interpretation from one device or application to
another can vary. Even colors in artwork created strictly for the Internet can vary
from monitor to monitor.
Furthermore, some elements of a FreeHand illustration may come from another
electronic device or another software application. One device or application's
interpretation of colors can differ from that of another device or application. Even
between devices or applications of the same type—or the same brand—color
interpretation can vary depending on age, wear, current settings, and other factors.
A color management system (CMS) interprets and translates color accurately
between devices. A CMS compares the color space (the gamut of colors a device
can display) in which a color was created to that in which the same color will be
output, and adjusts the color as needed to match the color on preview devices as
closely as possible to the color that will be produced in the final output (either
print or online).