Thermo Scientific VC-D60 Operating Manual page 34

Refractive index detector
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3
Device Overview
Page 34
When a change occurs in the refractive index of the mobile phase, the
light passing through the interface between the sample and reference
cells is refracted, causing the light intensity on one photodiode to
increase and on the other to decrease. This difference gives a signal
having both amplitude and polarity.
Refractive Index Detector (VC-D60)
Operating Manual

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