Miltenyi Biotec MultiMACS Cell24 Separator Plus User Manual
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Miltenyi Biotec MultiMACS Cell24 Separator Plus User Manual

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Summary of Contents for Miltenyi Biotec MultiMACS Cell24 Separator Plus

  • Page 1 MultiMACS™ Cell24 Separator Plus User manual...
  • Page 2 MultiMACS™ Cell24 Separator Plus may make copies solely for purposes of training personnel in the use and servicing of the unit within their business or organization. Maximal care has been taken by Miltenyi Biotec in the preparation of this user manual.
  • Page 3 MultiMACS™ Cell24 Separator Plus User manual Original instructions Miltenyi Biotec B.V. & Co. KG Friedrich-Ebert-Straße 68 51429 Bergisch Gladbach Germany Phone +49 2204 8306-0 Fax +49 2204 85197 macsde@miltenyi.com www.miltenyibiotec.com...
  • Page 4 If you have a serious concern regarding the safe use of your instrument, contact your authorized Miltenyi Biotec service provider or call Miltenyi Biotec Technical Support.

  • Page 5: Table Of Contents

    Content Important safety information Wichtige Sicherheitsinformationen Información importante de seguridad Informations de sécurité importantes 1 Introduction 2 Installation 2.1 Components 2.1.1 Components included in the delivery 2.1.2 Accessories 2.1.3 Consumables 2.2 Assembly for benchtop use 3 Operating the instrument 3.1 Switching on and off 3.2 Stopping a moving magnet 3.3 Menu 3.3.1 Start menu...
  • Page 6 4 Setting up an experiment 4.1 Process selection 4.2 Columns 4.3 Target cell fraction and waste container 4.4 Buffer volumes 4.5 Large sample volumes 4.6 Magnetic labeling 5 Pre-defined processes 5.1 DEPLETE 5.2 POSSEL 5.3 POSSEL_2 5.4 POSSEL_SCA 5.5 POSSEL2_SCA 6 Custom processes 6.1 Creating a process 6.2 Replacing a process...
  • Page 7 8.2 Collision detection 8.3 Vacuum failure 8.4 Failed elution of labeled cells 8.5 Poor elution recovery 8.6 Error codes 9 Technical data and specifications 9.1 Technical data 9.2 EC/EU Declaration of Conformity 9.2.1 MultiMACS Cell24 Separator 9.2.2 MACS Elution Station 10 Technical support 11 Limited warranty...

  • Page 9: Important Safety Information

    Important safety information The MultiMACS Cell24 Separator Plus is designed for safe use when installed correctly, operated by professional laboratory personnel, operated in accordance with general safety practices and the instructions in this user manual. Warnings and precautions The guidelines in this section explain the potential risk associated with operating this instrument and provide important supplemental safety information to minimize the risks.
  • Page 10 • Keep safety labels and safety markings clean and legible. • Inspect the safety labels and safety markings regularly and replace them if they are not legible or identifiable from a safe viewing distance. • Contact Miltenyi Biotec for replacement labels.
  • Page 11 Figure 1: The hazard points and the position of the safety symbols of the MultiMACS Cell24 Separator Plus. Safety label 1 and 3 WARNING! Extremely strong magnetic field. Risk of severe personal injury to persons carrying pacemakers or electronic medical implants – stay clear.
  • Page 12 If the instrument is not working properly and/or the displayed instructions or messages advise you to contact technical support, safe operation of the instrument is not longer possible. Immediately switch off and unplug the instrument from the power outlet and contact an authorized Miltenyi Biotec service provider or Miltenyi Biotec Technical Support.
  • Page 13 COM. In addition, only connect original MultiMACS Cell24 Separator Plus equipment to the connectors labeled module 1 and module 2, and connect only the MultiMACS Cell24 Separator Plus display to the connector labeled display. Only use connector cables less than 3 m in length.
  • Page 14 Biotec parts, or third-party parts specified and recommended by Miltenyi Biotec. Using unauthorized parts can cause malfunctions of the instrument and impair results. Miltenyi Biotec does not honor any warranty or accept any responsibility for instrument failure or damages resulting from the use of inappropriate parts. After completing any service or repair work, ensure that your authorized Miltenyi Biotec service provider performs all safety checks as required by the repair procedure to ensure that the instrument is operating correctly.
  • Page 15 For more information, or if you wish to dispose of your end-of-life Miltenyi Biotec equipment, please contact your local Miltenyi Biotec representative or Miltenyi Biotec Technical Support.

  • Page 17: Wichtige Sicherheitsinformationen

    Wichtige Sicherheitsinformationen Der MultiMACS Cell24 Separator Plus ist für einen sicheren Betrieb ausgelegt, wenn das Gerät richtig installiert, von professionellem Laborpersonal bedient und entsprechend der Sicherheitsrichtlinien und Anweisungen in diesem Benutzerhandbuch eingesetzt wird. Warn- und Sicherheitshinweise Die Sicherheitsrichtlinien in diesem Kapitel erläutern die Gefahren, die sich aus dem Betrieb dieses Gerätes ergeben können und enthalten wichtige zusätzliche Informationen wie diese Risiken zu minimieren sind.
  • Page 18 • Halten Sie die Warnaufkleber und Sicherheitskennzeichnungen sauber und lesbar. • Überprüfen Sie die Warnaufkleber und Sicherheitskennzeichnungen regelmäßig und ersetzen Sie diese, wenn sie nicht mehr lesbar oder aus sicherer Entfernung nicht zu erkennen sind. • Kontaktiern Sie Miltenyi Biotec, um Ersatzaufkleber zu erhalten.
  • Page 19 Figure 1: Warnhinweise und Position der Sicherheitssymbole auf dem MultiMACS Cell24 Separator Plus. Sicherheitsaufkleber 1 und 3 WARNUNG! Extrem starkes Magnetfeld. Gefahr schwerer Verletzungen für Personen mit Herzschrittmacher oder elektronischen medizinischen Implantaten. Abstand halten. Alle magnetisch empfindlichen Gegenstände vom Gerät fernhalten.
  • Page 20 Fremdkörper in das Gerät gefallen ist. Wenn Flammen oder Rauch auftreten, schalten Sie das Gerät unverzüglich aus, ziehen Sie den Netzstecker und kontaktieren Sie einen autorisierten Miltenyi Biotec Servicedienstleister oder den Miltenyi Biotec Technical Support. Das Gerät ist ausschließlich für den Betrieb in Innenräumen ausgelegt.
  • Page 21 An die mit External module 1 und module 2 beschrifteten Buchsen dürfen nur original MultiMACS Cell24 Separator Plus Geräte angeschlossen werden. Das MultiMACS Cell24 Separator Plus Display darf nur an die mit display gekennzeichnete Buchse angeschlossen werden. Es dürfen nur Anschlusskabel mit einer Länge von max.
  • Page 22 20 cm über und hinter dem MultiMACS Cell24 Separator Plus, damit das Gerät nach hinten kippen kann, um eventuelle Quetsch- und Scherverletzungen zu vermeiden sowie Schäden am Gerät zu minimieren. Schutzeinrichtungen oder -maßnahmen dürfen nicht umgangen werden. Bei manueller Bedienung muss der Schutzschirm (Protective Screen) am Gerät befestigt sein.
  • Page 23 Elektronik-Altgeräten sowie von Gefahrstoffen entsorgt wird, tragen Sie dazu bei, unsere natürlichen Ressourcen zu schonen und die menschliche Gesundheit zu schützen. Miltenyi Biotec setzt sich für den Schutz der Umwelt ein. Miltenyi Biotec bietet in zahlreichen Ländern eigene Rücknahmeprogramme für Altgeräte an und arbeitet weltweit mit lizensierten Partnern zusammen, die an bestehende Recycling- und Entsorgungssysteme angeschlossen sind.

  • Page 25: Información Importante De Seguridad

    Información importante de seguridad El MultiMACS Cell24 Separator Plus está diseñado para un uso seguro si se instala correctamente, y se maneja por personal de laboratorio profesional de acuerdo con las prácticas generales de seguridad y las instrucciones de este manual de usuario.
  • Page 26 • Mantenga las etiquetas y marcas de seguridad en un estado limpio y legible. • Inspeccione las etiquetas y marcas de seguridad con regularidad, y reemplácelas si no son legibles o identificables desde una distancia de visualización segura. • Póngase en contacto con Miltenyi Biotec si necesita etiquetas de recambio.
  • Page 27 Figure 1: Los puntos de peligro y la posición de los símbolos de seguridad del MultiMACS Cell24 Separator Plus. Etiqueta de seguridad 1 y 3 ADVERTENCIA! Campo magnético extremadamente fuerte. Riesgo de lesiones personales graves para las personas que llevan marcapasos o implantes médicos electrónicos: manténgase alejado.
  • Page 28 Si aparecen llamas o humo, inmediatamente apague la fuente de energía, desenchufe el instrumento de la toma de corriente, y póngase en contacto con un proveedor de servicio técnico autorizado de Miltenyi Biotec o el Miltenyi Biotec Technical Support.
  • Page 29 Si tiene preguntas sobre el tipo de fuente de energía que usar, póngase en contacto con su proveedor de servicios autorizado de Miltenyi Biotec o una compañía de energía local. No use alargadores o enchufes múltiples. No sobrecargue una toma de corriente.
  • Page 30 No coloque ningún objeto encima del MultiMACS Cell24 Separator Plus. Deje un espacio de 20 cm por encima y detrás el MultiMACS Cell24 Separator Plus para permitir que el instrumento pueda inclinarse hacia atrás, evitando así...
  • Page 31 Información sobre la Directiva de Residuos de Aparatos Eléctricos y Electrónicos (RAEE) Por favor, al final de la vida útil de su equipo de Miltenyi Biotec disponga del mismo de acuerdo a la ley RAEE aplicable, la cual puede ser diferente según el país o región.

  • Page 33: Informations De Sécurité Importantes

    Informations de sécurité importantes Le MultiMACS Cell24 Separator Plus est conçu pour une utilisation sûre, si il est correctement installé et manié par des personnel de laboratoire professionnel, conformément aux mesures de sécurité générales et aux consignes libellées dans ce manuel.
  • Page 34 RISQUE D'ÉCRASEMENT ET DE CISAILLEMENT DES MEMBRES CORPORELS. DANGER BIOLOGIQUE. RISQUE DE CONTAMINATION, SI DES MATIÈRES BIOLOGIQUES POTENTIELLEMENT DANGEREUSES SONT UTILISÉES. ON (ALIMENTATION ÉLECTRIQUE). OFF (ALIMENTATION ÉLECTRIQUE). BORNE POUR CONDUCTEUR DE PROTECTION. CE SYMBOLE EST FIXÉ À L'INTÉRIEURE DE L'APPAREIL. CETTE INFORMATION EST DESTINÉE AU PERSONNEL DE SERVICE.
  • Page 35 Figure 1: Points dangereux et emplacement des symboles de sécurité du MultiMACS Cell24 Separator Plus. Étiquette de sécurité 1 et 3 AVERTISSEMENT! Champ magnétique extrêmement puissant. Les personnes portant un stimulateur cardiaque ou un implant médical électronique courent un risque de blessure grave. Elles doivent rester à distance. Maintenir tous les objets sensibles aux champs magnétiques à...
  • Page 36 étranger a pénétré dans l'appareil. Si des flammes ou la fumée apparaissent, coupez immédiatement l'alimentation électrique, débranchez l'appareil de la prise électrique, puis contactez un prestataire de services Miltenyi Biotec agréé ou l'équipe de support technique de Miltenyi Biotec.
  • Page 37 Si un objet a été placé par inadvertance sous l’aimant se déplaçant en bas, la résistance physique de l’objet peut faire basculer l’appareil vers l’arrière, de la même façon qu’un vérin hydraulique. Ne placez pas d’objets sur le MultiMACS Cell24 Separator Plus. Laissez un espace libre d’au moins 20 cm au-dessus et derrière le MultiMACS...
  • Page 38 Pour utiliser le séparateur MultiMACS intégré dans un système automatisé de manipulation de liquides compatible, veillez à ce que le système combiné, c’est-á-dire le MultiMACS Cell24 Separator Plus, l'aimant MultiMACS Cell24 et le robot de manipulation de liquides, réponde á toutes les exigences de sécurité et d’utilisation avant de commencer les processus automatisés.
  • Page 39 Miltenyi Biotec qui vous aidera. Déchets d’Equipements Electriques et Electroniques (DEEE) – Information Client Pensez à recycler vos produits Miltenyi Biotec en fin de vie en conformité avec la directive DEEE en vigueur dans votre pays.

  • Page 41: Introduction

    Alternatively, up to 12 LS, LD, or Whole Blood Columns can be used in combination with the MultiMACS Single-Column Adapter. Deep well plates and 5 mL tubes can be used for sample collection. Figure 1.1: Front view of the MultiMACS Cell24 Separator Plus with MACS Elution Station (left) and MultiMACS Cell24 Separator (right).
  • Page 42 Figure 1.2: Side view of the MultiMACS Cell24 Separator Plus. Figure 1.3: Connectors on the rear side of the MultiMACS Cell24 Separator. Figure 1.4: Rear side of the MACS Elution Station with connectors (left) and vacuum chamber (right).
  • Page 43 Figure 1.5: MACS Elution Chamber, including a 24-well Deep Well Plate and lid I. Figure 1.6: MACS Elution Chamber with lid II.

  • Page 45: Installation

    Components 2.1.1 Components included in the delivery The following components are included in the delivery of the MultiMACS Cell24 Separator Plus (#130-098-637). Component MultiMACS Cell24 Separator MACS Elution Station MACS Elution Chamber (including lid I for elution into standard deep well plates and lid II for elution into 5 mL...

  • Page 46: Accessories

    Assembly for benchtop use Leave a space of at least 20 cm distance above the MultiMACS Cell24 Separator Plus to ensure that the instrument is able to tilt backwards, thus minimizing damage. If an object has been accidentally placed under the down-moving MultiMACS Cell24 Magnet, the physical resistance of the object causes the instrument to tilt backwards similar to a hydraulic jack.
  • Page 47 The filter can be only screwed in to half the length of the screw thread. 9 Connect the power cable to the outlet on the rear side of the MultiMACS Cell24 Separator and plug it into an appropriate power socket. 10 Attach the magnetic Column Blank Holder to the MultiMACS Cell24 Separator Plus.
  • Page 48 The MultiMACS Cell24 Separator Plus can be integrated into liquid-handling systems for automated use. For further information refer to the Miltenyi Biotec Technical Support or visit www.miltenyibiotec.com for our instrument portfolio.

  • Page 49: Operating The Instrument

    MultiMACS Cell24 Magnet and the MultiMACS Column Holder. Do not remove the protective screen if the MultiMACS Cell24 Separator Plus is operated manually in a semi- automated mode. Remove the protective screen only if used in liquid-handling platforms as it can interfere with gripping plates.

  • Page 50: Menu

    2 Tap OK to continue, tap MOVE BACK to move the MultiMACS Cell24 Magnet to the last position, or tap ESC to abort the process. Menu The following chart shows the software menu structure of the MultiMACS Cell24 Separator Plus. Figure 3.1: The software menu structure. 3.3.1 Start menu Start menu the following three options are available.

  • Page 51: Process Menu

    Exchange the MultiMACS Cell24 Magnet. Lock the MultiMACS Cell24 Magnet for transport. Show the firmware version. Turn on or off the sound. Figure 3.4: Set up screen of the MultiMACS Cell24 Separator Plus. 3.3.4 New process Go to NEW to create a custom process. The menu leads through the parameter adjustment of all process steps.

  • Page 52: Instructions For Use

    3.5.1 Placing columns into the MultiMACS Column Holder Do not place columns into the MultiMACS Cell24 Separator Plus until the prompt screen INSERT COLUMNS appears to ensure that there are no moving parts when placing the columns. This will prevent injuries to fingers that can otherwise become trapped between the MultiMACS Cell24 Magnet and the MultiMACS Column Holder.

  • Page 53: Placing Plates

    1 The MultiMACS Cell24 Magnet moves into the start position. 2 When the instrument prompts you to do so, insert or remove the Multi-24 Column Block or the MultiMACS Single-Column Adpater. The Multi-24 Column Block and the MultiMACS Single-Column Adpater can be only inserted in one direction.

  • Page 54: Collecting The Unlabeled Fraction

    3.5.3 Collecting the unlabeled fraction 1 For application of samples and buffer the MultiMACS Cell24 Magnet and the MultiMACS Column Holder move down. 2 Apply buffer or sample depending on the process step. Equilibrate columns just before the separation. Do not store equilibrated columns. 3.5.4 Tip-Touch The Tip-Touch Plate is used for the removal of residual drops from the column tips.

  • Page 55: Collecting The Labeled Fraction

    3.5.5 Collecting the labeled fraction The MACS Elution Station enables the elution of the magnetically labeled cells from MACS Columns when performing a positive selection. It generates a gentle vacuum impulse to elute the cells from the columns. 1 Insert a deep well plate or a MultiMACS 5mL Tube Rack into the base of the MACS Elution Chamber. 2 Place the lid on top of the MACS Elution Chamber.

  • Page 56: Running A Process

    4 When using the MultiMACS Single-Column Adapter close unused positions with the respective number of Column Blanks. All 12 positions of the MultiMACS Single-Column Adapter need to be closed to ensure sufficient vacuum. 5 Apply the elution impulse. Running a process 1 Go to the Process menu of the process you want to run.

  • Page 57: Setting Up An Experiment

    Process selection Select an appropriate cell isolation process depending on the desired target cell fractions, isolation strategy, and column type. The last cell isolation process performed on the MultiMACS Cell24 Separator Plus is shown on the upper left of the screen.

  • Page 58: Columns

    Use the MultiMACS Single-Column Adapter to process up to 12 samples or whole blood and to insert LS, LD, or Whole Blood Columns into the MultiMACS Cell24 Separator Plus. For more than 12 samples use the Multi-24 Figure 4.1 ).

  • Page 59: Target Cell Fraction And Waste Container

    Target cell fraction and waste container To collect target cells deep well plates or 5 mL tubes can be used. The default target cell container in the pre- defined processes is a deep well plate with a height of 44.0 mm. Table 4.2 shows the number of deep well plates required for each pre-defined process.

  • Page 60: Buffer Volumes

    Buffer volumes Apply the following buffer volumes according to the column type and workflow. Column type Equilibration Wash Elution Multi-24 Column Block 1×2 mL 3×1 mL 1×1 mL LS Column 1×3 mL 2×2 mL 1×4 mL LD Column 1×2 mL 2×1 mL 1×3 mL Whole Blood Column 1×3 mL 2×2 mL 1×4 mL Table 4.4: Buffer volumes required for different column types.

  • Page 61: Pre-Defined Processes

    MultiMACS Cell24 Magnet and the MultiMACS Column Holder. The following five processes are pre-defined on the MultiMACS Cell24 Separator Plus. The programs are suitable for collection of the unlabeled fraction in 24-well deep well plates. For the collection in 5 mL tubes create a Creating a process on page 65 ).

  • Page 62: Possel

    11 REMOVE COLUMNS, PRESS OK TO END PROCESS : Remove the columns containing the labeled cells. OK . 12 Proceed to downstream applications with the unlabeled cells from the flow through fraction. POSSEL 1 Select POSSEL in the Start menu. The Process menu opens. Tap the Run button. 2 INSERT COLUMNS : Insert the Multi-24 Column Block into the MultiMACS Column Holder.

  • Page 63: Possel_Sca

    The MACS Elution Station will generate a vacuum. The status LED blinks green or red during this process. When the vacuum has been established, the status LED lights up constantly green. 7 APPLY SAMPLE AND WASH : Apply the suspension of magnetically labeled cells onto each column and let it run through.

  • Page 64: Possel2_Sca

    When exceeding a volume of 5 mL, load the sample in two steps onto the column. Tap MOVE BACK after applying the first 5 mL. Exchange the deep well plate after movement of the magnet. Tap OK to proceed with sample loading. Alternatively, a 88 mm deep well plate can be used. 6 Apply degassed wash buffer onto each column and let it run through.
  • Page 65 7 APPLY SAMPLE AND WASH : Apply the suspension of magnetically labeled cells onto each column and let it run through. When exceeding a volume of 5 mL, load the sample in two steps onto the column. Tap MOVE BACK after applying the first 5 mL.

  • Page 67: Custom Processes

    Custom processes Custom processes can be defined, for example when plates with other than the default settings are used. Refer Target cell fraction and waste container on page 57 . Up to 10 custom processes can be save to the process list. If exceeding this process number when creating a new process, an obsolete process has to be replaced.
  • Page 68 7 Select a waste plate. The waste will be collected in a deep well plate. The default height of the waste plate is 44.0 mm. Tap DWB (44.0 mm) to select the default height. 8 Option: Scroll down and tap ENTER HEIGHT to enter a different plate height in the next screen. 9 To adjust the plate height tap +0.5 MM or +5 MM to increase and -0.5 MM or -5 MM to decrease the value.

  • Page 69: Replacing A Process

    14 Tap YES to start the process or NO to go to the Start menu. Replacing a process If 10 custom processes have already been saved in the process list, an obsolete process has to be replaced. 1 When trying to save a new process the following screen is shown. Select a process you want to delete and tap the process name.

  • Page 70: Changing Parameters

    5 Tap SAVE PROCESS TO LIST or MORE CHANGES to return to the edit function. 6 After the process has been saved, tap YES to start the process or tap NO or ESC to return to the Start menu. 6.3.2 Changing parameters 1 Go to the Process menu of the process you want to edit and tap EDIT .
  • Page 71 2 Insert the Multi-24 Colum Block or the MultiMACS Single-Column Adapter. Tap OK . The MultiMACS Cell24 Magnet moves up to the next position. 3 Place the plate to be tested. Tap OK and the MultiMACS Cell24 Magnet will move down to the next position. 4 Check whether the height is acceptable by moving the Tip-Touch Plate back and forth.

  • Page 73: Maintenance

    Important safety information . Do not service the equipment yourself. Service shall be Read the chapter carried out only by trained experts authorized by Miltenyi Biotec. An improperly serviced instrument may lead to severe personal injury or death by exposure to mechanical hazards, hazardous optical radiation, and the risk of electric shock.

  • Page 74: Rotating The Multimacs Cell24 Magnet And Multimacs Column Holder

    Rotating the MultiMACS Cell24 Magnet and MultiMACS Column Holder The MultiMACS Cell24 Separator Plus is equipped with an extremely powerful magnet, the MultiMACS Cell24 Magnet. Keep this magnet at a distance of at least 20 cm from any magnetic information carriers such as credit cards, magnetic tapes, and storage media, and from any electronic equipment, such as hearing aids, pacemakers, brain shunts, measuring and control instruments, computers, and watches.
  • Page 75 Cell24 Magnet and the MultiMACS Column Holder (refer to Figure 7.1 ). 11 Fasten the knurled screws. 12 Plug in the power cable. Figure 7.1: MultiMACS Cell24 Separator Plus with installed MultiMACS Cell24 Magnet and MultiMACS Column Holder in landscape orientation (left) and portrait orientation (right).

  • Page 76: Exchanging Fuses

    4 Tap this button and the current version of the firmware is shown in the next screen. Preparating for transport Keep away from all moving parts! Contact Miltenyi Biotec before shipping. The MultiMACS Cell24 Separator Plus has to be locked before shipping. 1 Tap SET UP in the Start menu. 2 Tap PREFERENCES .
  • Page 77 6 Detach the Tip-Touch Plate. 7 Disconnect the MACS Elution Chamber. Push the tube connection ring towards the MACS Elution Chamber and simultaneously pull out the tube connector. 8 The MultiMACS Cell24 Separator Plus is now ready for shipping.

  • Page 79: Troubleshooting

    Cleaning the instrument on page 71 . Collision detection If a tilting of the MultiMACS Cell24 Separator Plus is registered while the MultiMACS Cell24 Magnet is moving, the movement stops and the following screen is shown. 1 If no blocking objects are visible, tap RETRY .

  • Page 80: Failed Elution Of Labeled Cells

    MACS Elution Chamber are assembled correctly without tilting. the lid of the MACS Elution Chamber and labware sealing are dust free, intact, and positioned correctly. If the problem persists or if a sealing has to be changed, please contact Miltenyi Biotec Technical Support. Error codes All errors are coded.

  • Page 81: Technical Data And Specifications

    Technical data and specifications The MultiMACS Cell24 Separator Plus is labeled as a protection class I device and must be plugged into a grounded power outlet. Supply voltage fluctuations up to +/– 10% of the nominal voltage. Transient over-voltages present on the mains supply: category II.

  • Page 82: Technical Data

    Technical data Technical data Specification Model MultiMACS Cell24 Separator Size (w x d x h) 230 mm x 435 mm x 230 mm (9.1" x 17.1" x 9.1") Weight 11 kg Input voltage 100–240 V~, 50/60 Hz Electric current 3.5 A max. Power consumption 200 W Fuses...
  • Page 83 Technical data Specification Model MACS Elution Station Size (w x d x h) 114 mm x 265 mm x 233 mm (4.5" x 10.4" x (9.2") Weight 4.6 kg Input voltage 24 V Electric current 0.875 A Power consumption 21 W RS232-Interface (labeled "RS232/Display") Pin 1, 4, 6, 7, 8: NC Pin 2: RXD...

  • Page 84: Ec/Eu Declaration Of Conformity

    EC/EU Declaration of Conformity 9.2.1 MultiMACS Cell24 Separator This declaration of conformity is issued under the sole responsibility of the manufacturer: Miltenyi Biotec B.V. & Co. KG Friedrich-Ebert-Straße 68 51429 Bergisch Gladbach Germany This declaration relates exclusively to the machinery in the state in which it was placed on the market, and excludes components which are added and/or operations carried out subsequently by the final user.

  • Page 85: Macs Elution Station

    9.2.2 MACS Elution Station This declaration of conformity is issued under the sole responsibility of the manufacturer: Miltenyi Biotec B.V. & Co. KG Friedrich-Ebert-Straße 68 51429 Bergisch Gladbach Germany This declaration relates exclusively to the machinery in the state in which it was placed on the market, and excludes components which are added and/or operations carried out subsequently by the final user.

  • Page 87: Technical Support

    Technical support For technical support, contact your local Miltenyi Biotec representative or Miltenyi Biotec Technical Support at Miltenyi Biotec headquarters: Miltenyi Biotec B.V. & Co. KG Friedrich-Ebert-Straße 68 51429 Bergisch Gladbach Germany Phone +49 2204 8306-830 Fax +49 2204 8306-89 macstec@miltenyi.com...

  • Page 89: Limited Warranty

    VOID AND CANCEL ALL WARRANTIES WITH RESPECT TO THE AFFECTED PRODUCT. Miltenyi Biotec’s warranty does not cover products sold AS IS or WITH ALL FAULTS, or which had its serial number defaced, altered or removed, or any consumables, or parts identified as being supplied by a third party.
  • Page 90 Miltenyi Biotec's option, to make repairs, replacements or corrections to the product or any component thereof as may be required to restore the full usability of your product. If Miltenyi Biotec determines that a product for which you have requested warranty services is not covered by the warranty hereunder, you shall pay or reimburse Miltenyi Biotec for all costs of investigating and responding to such request at Miltenyi Biotec’s then...
  • Page 92 Miltenyi Biotec provides products and services worldwide. Visit www.miltenyibiotec.com/local to find your nearest Miltenyi Biotec contact. Unless otherwise specifically indicated, Miltenyi Biotec products and services are for research use only and not for therapeutic or diagnostic use. MACS, the Miltenyi Biotec logo, MultiMACS, and StraightFrom are registered trademarks or trademarks of Miltenyi Biotec and/or its affiliates in various countries worldwide.

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