Incorrect Qualitative/Quantitative Results - Waters 2410 Operator's Manual

Table 7-3 Resolution Troubleshooting (Continued)
Symptom
Flat-topped peaks

7.2.4 Incorrect Qualitative/Quantitative Results

If a peak is incorrectly identified by a data system or integrator, make sure that the
retention time is correct.
If retention times are correct and peak resolution is good, the cause of qualitative and
quantitative errors is not likely to be chromatographic; it is more likely due to inadequate
sample preparation or faulty processing of the data (integration).
To troubleshoot problems with qualitation and/or quantitation, refer to
Artisan Technology Group - Quality Instrumentation ... Guaranteed | (888) 88-SOURCE | www.artisantg.com
Possible Cause Corrective Action
Detector not zeroed Auto zero detector
baseline.
Incorrect recorder input Adjust recorder input
voltage voltage, or adjust detector
output cable to correct
position.
Sensitivity too high Select a lower sensitivity.
Scale factor too high Select a lower scale factor.
(recorder only)
Sample concentration or Decrease sample
injection volume exceeds concentration or injection
voltage output of detector volume.
Chromatography Troubleshooting
7
Table 7-4.
98