Prevent Blocking Of Solvent Filters - Agilent Technologies InfinityLab LC Series User Manual

3 Using the Pump

Prevent Blocking of Solvent Filters

Prevent Blocking of Solvent Filters

Contaminated solvents or algae growth in the solvent bottle will reduce the
lifetime of the solvent filter and will influence the performance of the module.
This is especially true for aqueous solvents or phosphate buffers (pH 4 to 7). The
following suggestions will prolong lifetime of the solvent filter and will maintain
the performance of the module.
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Never use the system without solvent filter installed.
NOTE
Agilent InfinityLab LC Series 1260 Infinity II Isocratic and Quaternary Pumps User Manual
Use a sterile, if possible amber, solvent bottle to slow down algae growth.
Filter solvents through filters or membranes that remove algae.
Exchange solvents every two days or refilter.
If the application permits add 0.0001 – 0.001 M sodium azide to the solvent.
Place a layer of argon on top of your solvent.
Avoid exposure of the solvent bottle to direct sunlight.
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