Waters ACQUITY UPLC I-Class IVD Overview And Maintenance Manual page 60

Column heater
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4 Maintenance Procedures
Recommended routine maintenance schedule: (Continued)
Maintenance
procedure
Replace the
column in-line
filter frit
Replace the
column in-line
filter unit
Clean the
device's exterior
with a soft,
lint-free cloth,
or paper
dampened with
water
60
September, 2019, 715003738IVD Rev. C
Frequency
Replace as part of the annual scheduled
routine maintenance and, thereafter, as
needed. The typical failure modes are as
follows:
• High back pressure. The column in-line
filter causes a high-pressure shutdown.
In this case, disconnect the column. If the
system exhibits pressure decay, inspect
the system pressure at known conditions.
Replace the frit.
• Leak. The system exhibits low back
pressure or shorter retention times.
As needed. The typical failure modes are as
follows:
• High back pressure. The column in-line
causes a high-pressure shutdown. In this
case, disconnect the in-line filter. If the
system exhibits pressure decay, inspect
the system pressure at known conditions.
Replace the frit or entire in-line filter
assembly.
• Leak. This can be detected visibly, using
the leak sensor or by noticing that the
peak retention times vary.
• Split peaks. Replace the filter frit.
Perform as part of your annual routine
scheduled maintenance and when solvent or
dust accumulates.
For
information
See
page
77.
See
page
77.
See
page
79.

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