General Notes For Degasser Operation - Thermo Scientific Dionex UltiMate 3000 Series Operating Instructions Manual

5.2 General Notes for Degasser Operation

In normal operation, the degasser is quiet. Even if the vacuum pump is running, the
operating noise is very low. With higher load, the operating noise may slightly increase.
However, this does not impair the degassing performance.
In addition, observe the following to ensure optimum degassing performance:
• Thermo Fisher Scientific recommends filling all channels with eluent and degassing all
channels (even if they are not used for the application). This will reduce the speed of the
vacuum pump and reduce the degasser noise.
• To avoid contamination of the degasser, you should prepare fresh solvents, clean the
solvent supply lines, and rinse the degassing channels at regular intervals (→ page 46).
Thermo Fisher Scientific advises against recycling the solvents. This may impair the
•
degassing performance.
• Before connecting the solvent supply lines, make sure that the connectors are free of
contaminants. Even minute particles can allow air to enter the degasser, and thus reduce
the degassing effectiveness.
• When replacing solvents, make sure that the solvents are miscible. Mix immiscible
solvents with an intermediate solvent to replace them step-by-step.
• Thoroughly rinse the degasser with methanol or isopropanol after operation. The alcohol
does not need to be removed afterward.
• For longer periods of inactivity and when using saliferous buffers (which may result in
salt crystallization in the gas separation membrane, thereby impairing the degassing
performance), rinse with de-ionized water followed by either methanol or isopropanol.
• Also, observe the information about the solvent compatibility of the degasser
(→ page 29).
Operating Instructions
UltiMate 3000 Series:
SRD-3x00 Solvent Racks
Page 31