Pilogel Iontophoretic Discs; Sensor Cell - Elitech NANODUCT 1030 User Manual

Section 1: Introduction
Pilogel
Iontophoretic
Discs

Pilogel Iontophoretic Discs

Pilogel discs are small (surface area 2.5 cm
inserted into the electrode assemblies before iontophoresis. Designed especially
for neonates, these discs have a pilocarpine concentration of 1.5% for optimum
stimulation of the sweat gland, which also reduces the iontophoresis time to
approximately 2.5 minutes.
Pilogel discs contain sufficient glycerol to provide substantial protection of gels
against damage from accidental freezing. Cracked discs due to freezing can
contribute to burns. Refer to the appendix for more information.
Pilogel discs contain trisodium citrate, an excellent buffer in the acid range of pH.
This reduces anodic acidification of the gel during iontophoresis by 90%. At the
cathode, the increased pilocarpine, a good buffer at moderately alkaline pH, also
reduces iontophoretic accumulation of alkali. This buffering prevents skin burns
due to pH change in the gel. Each of these features contributes to the safety of
the procedure. Refer to Appendix H for important information about pilocarpine
iontophoresis.
In areas where Pilogel discs are not available, users should check with
ELITechGroup for the availability of fiber pilocarpine reservoirs of the same
size as Pilogel discs, for use with pilocarpine solutions supplied by the
user.
WARNING!
Pilogel discs should be refrigerated at 2 to 8 °C. DO NOT FREEZE. Never
use discs that have been frozen or that are cracked. This does NOT apply
to fiber pilocarpine reservoirs.
WARNING!
Pilogel is considered toxic, as is pilocarpine nitrate in other forms. Do not
ingest. See Appendix D, E, or the SDS.

Sensor Cell

Color-coded red, the sensor has two external flanges (as with the electrodes) for
latching to the red holder. The base of the sensor is a shallow concavity leading
at its center to an entry port, and from there to a fine internal channel passing by
two analyzer micro-electrodes, forming a micro conductivity cell.
The sensors pass through stringent quality controls before shipment to the
customer. To be accepted, sensors must be highly consistent throughout each
batch.
) iontophoretic discs that are
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