Cleaning Procedure - Thermo Scientific Prima PRO User Manual

Mass spectrometers
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Cleaning Procedure

Thermo Fisher Scientific
12. Reverse the above procedure to reassemble the system. Always
leak check the system after reassembly.
13. If there is any sign of contamination in the valve manifold it is
advisable to remove all valves from the manifold to enable full
cleaning. Keep the valve assemblies separate and in sequence, so
that the valves can be replaced into the same manifold ports.
Particulate contamination should be removed initially by blowing
with a clean inert gas such as nitrogen. More stubborn contamination
can be removed by wiping with a tissue moistened with clean
isopropanol (specifically, free from non-volatile impurities) or
another suitable solvent. Difficult to access regions may require
cleaning in an ultrasonic bath. Do not use this procedure for cleaning
elastomer seals as it can cause the seal to harden. All metallic parts
can be solvent cleaned.
To remove contamination by process fluids, some knowledge of the
contaminant is required, from both a safety perspective and in order
to choose a suitable solvent or cleaning fluid. Accessible areas can be
mechanically cleaned, providing sealing surfaces are not damaged.
Final cleaning should always involve the use of a clean solvent
(isopropanol etc., as above) to remove any cleaning residues, grease,
etc. Excess solvent should be blown from the inlet components using
an inert gas. If possible, components should be dried in an oven at
temperatures up to 60°C.
Remember to clean external pipe work and gas conditioning
equipment to avoid recontamination. The cause of the contamination
should be investigated and rectified before putting back into service.
Prima PRO & Sentinel PRO Mass Spectrometers User Guide
Technical Description: Inlet
Solenoid Inlet
C-39

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