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Audience and purpose
This guide is intended for use by individuals who must install, operate, maintain, or
troubleshoot the 2414 Reflective Index (RI) detector.
This guide sets forth procedures for unpacking, installing, using, maintaining, and
troubleshooting the 2414 RI detector. It also includes appendices for safety warnings
and specifications.
Intended use of the 2414 Refractive Index Detector
Waters designed the 2414 RI detector for high-performance liquid chromatography
(HPLC) applications. It provides sensitivity, stability, and reproducibility for the
analysis of components with limited or no UV absorption. The 2414 RI detector is not
intended for use in diagnostic applications.
Calibrating
To calibrate LC systems, follow acceptable calibration methods using at least five
standards to generate a standard curve. The concentration range for standards must
include the entire range of QC samples, typical specimens, and atypical specimens.
Quality control
Routinely run three QC samples that represent subnormal, normal, and above-normal
levels of a compound. If sample trays are the same or very similar, vary the location
of the QC samples in the trays. Ensure that QC sample results fall within an
acceptable range, and evaluate precision from day to day and run to run. Data
collected when QC samples are out of range might not be valid. Do not report these
data until you are certain that the instrument performs satisfactorily.
EMC considerations
Canada spectrum management emissions notice
This class A digital product apparatus complies with Canadian ICES-001.
Cet appareil numérique de la classe A est conforme à la norme NMB-001.
ISM Classification: ISM Group 1 Class B
This classification has been assigned in accordance with IEC CISPR 11 Industrial
Scientific and Medical (ISM) instruments requirements.
Definition
Part number catalog number
June 11, 2015, 715004754 Rev. A
Page vii
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Table of Contents
Troubleshooting
