Audience And Purpose; Intended Use Of The Acquity Qda Detector; Calibrating; Quality-Control - Waters ACQUITY QDa Overview And Maintenance Manual

Audience and purpose

This guide is for novice users, and assumes no knowledge of liquid chromatography or mass
spectrometry principles. It provides an overview of the instrument and explains how to install it,
prepare it for operation, and maintain it.

Intended use of the ACQUITY QDa Detector

Waters designed the ACQUITY QDa Detector for use as an ion confirmation and quantitation tool,
as part of an ACQUITY UPLC or UPC
ACQUITY QDa Detector is not intended for use in diagnostic applications.

Calibrating

To calibrate LC/MS systems, follow acceptable calibration methods using at least five standards to
generate a standard curve. The concentration range for standards should include the entire range
of QC samples, typical specimens, and atypical specimens.

Quality-control

Routinely run three QC samples that represent subnormal, normal, and above-normal levels of a
compound. If sample trays are the same or very similar, vary the location of the QC samples in the
trays. Ensure that QC sample results fall within an acceptable range, and evaluate precision from
day to day and run to run. Data collected when QC samples are out of range might not be valid. Do
not report these data until you are certain that the instrument performs satisfactorily.
EMC considerations
Canada spectrum management emissions notice
This class A digital product apparatus complies with Canadian ICES-001.
Cet appareil numérique de la classe A est conforme à la norme NMB-001.

ISM Classifickation: ISM Group 1 Class A

This classification has been assigned in accordance with CISPR 11 Industrial Scientific and
Medical, (ISM) instrument requirements.
Group 1 products apply to intentionally generated and/or used conductively coupled
radio-frequency energy that is necessary for the internal functioning of the equipment.
Class A products are suitable for use in all establishments other than residential locations and
those directly connected to a low voltage power supply network supplying a building for domestic
purposes.
There may be potential difficulties in ensuring electromagnetic compatibility in other environments
due to conducted as well as radiated disturbances.
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system, Alliance, and LC and SFC prep systems. The
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