Product Description; Intended Use; Principle Of The Ngs Prep Procedure; Limitations Of Use - Agilent Technologies Magnis G9710A User Manual

Product Description

The Magnis NGS Prep System is an automated liquid handling system for next generation
sequencing library preparation and/or target enrichment of human nucleic acid samples.

Intended Use

The MagnisDx NGS Prep System is an automated liquid handling system for next generation
sequencing library preparation and/or target enrichment of human nucleic acid samples.
The MagnisDx NGS Prep System is to be used only by operators trained in laboratory techniques
and procedures.
The customer is responsible for validation of assays and compliance with regulatory
requirements that pertain to their procedures and uses of the instrument.

Principle of the NGS Prep Procedure

The Agilent Magnis/MagnisDx NGS Prep System is a liquid handler that offers start-to-finish
automation of library preparation and target enrichment protocols for next generation sequencing
(NGS). The starting material is fragmented genomic DNA (gDNA) purified from a cell or tissue
sample, blood sample, or formalin-fixed paraffin-embedded (FFPE) sample. The end result is a
target-enriched DNA library ready for sequencing.
The hardware components make up the instrument. See
for a list of these components.
The instrument is controlled through the software component of the system, which is displayed
and operated through the LCD touchscreen. Chapter
"Operating the System,"
NGS Prep System using the software. Chapter
description of each individual software screen, detailing the purpose of each feature on the
screen.

Limitations of Use

The Magnis/MagnisDx NGS Prep System has been validated for use with Agilent Magnis NGS
kits.
Magnis and MagnisDx NGS Prep System User Guide
include instructions on setting up and operating the Magnis/MagnisDx
6, "Software User Interface Reference,"
"Instrument Components"
3, "Getting Started," and Chapter
on page 16
4,
provides a
9