How To Use Miscibility Numbers - Waters 2489 Overview And Maintenance Manual

Table C–1:
Polarity
Solvent
index
2.2 Isopropyl ether
2.3 Toluene
2.4 P-xylene
3.0 Benzene
3.3 Benzyl ether
3.4 Methylene chloride
3.7 Ethylene chloride
3.9 Butyl alcohol
3.9 Butanol
4.2 Tetrahydrofuran
4.3 Ethyl acetate
4.3 1-propanol
4.3 2-propanol
4.4 Methyl acetate
4.5 Methyl ethyl ketone
4.5 Cyclohexanone
4.5 Nitrobenzene
4.6 Benzonitrile
4.8 Dioxane
5.2 Ethanol
5.3 Pyridine
5.3 Nitroethane
5.4 Acetone
5.5 Benzyl alcohol
5.7 Methoxyethanol
6.2 Acetonitrile
6.2 Acetic acid
6.4 Dimethylformamide
6.5 Dimethylsulfoxide
6.6 Methanol
7.3 Formamide
9.0 Water
C.2.1 How to use miscibility numbers
Use miscibility numbers (M-numbers) to predict the miscibility of a liquid with a
standard solvent (see
Solvent miscibility: (continued)
Viscosit
y CP, 20
°C
0.33
0.59
0.70
0.65
5.33
0.44
0.79
3.00
3.01
0.55
0.47
2.30
2.35
0.45
0.43
2.24
2.03
1.22
1.54
1.20
0.94
0.68
0.32
5.80
1.72
0.37
1.26
0.90
2.24
0.60
3.76
1.00
"Solvent miscibility" on page
June 11, 2015, 715004752 Rev. A
Boiling
point °C
(1 atm)
68.3
100.6
138.0
80.1
288.3
39.8
83.5
117.7
177.7
66.0
77.1
97.2
117.7
56.3
80.0
155.7
210.8
191.1
101.3
78.3
115.3
114.0
56.3
205.5
124.6
81.6
117.9
153.0
189.0
64.7
210.5
100.0
142).
Page 143
Miscibilit
λ
y number Cutoff
(M) (nm)
–– 220
23 285
24 290
21 280
–– ––
20 245
20 ––
––- ––
15 ––
17 220
19 260
15 210
15 ––-
15, 17 260
17 330
28 210
14, 20 ––
15, 19 ––
17 220
14 210
16 305
–– ––
15, 17 330
13 ––
13 ––
11, 17 190
14 ––
12 ––
9 ––
12 210
3 ––
–– ––