Thermo Scientific Orbitrap Fusion Lumos Getting Started Manual page 111

n = 2 corresponds to an MS
two stages of mass analysis. A scan power of n = 3
3
corresponds to an MS
analysis, and so on.
selected ion monitoring (SIM) scan type A scan type
where the mass spectrometer acquires and records ion
current following the isolation of a range of mass-to-
charge ratio values.
sheath gas The inner coaxial gas (nitrogen), which is
used in the API source to help nebulize the sample
solution into a fine mist as the sample solution exits
the H-ESI or APCI nozzle.
signal-to-noise ratio (S/N) The ratio of the signal
height (S) to the noise height (N). The signal height
is the baseline corrected peak height. The noise
height is the peak-to-peak height of the baseline
noise.
sweep gas Nitrogen gas that flows out from the gap
between the sweep cone and the ion transfer tube
into the API source. Sweep gas aids in solvent
declustering and adduct reduction.
syringe pump A device that delivers a solution from a
syringe at a specified rate.
T
total ion current (TIC) The sum of the ion current
intensities across the scan range in a mass spectrum.
U
ultraviolet photodissociation (UVPD) A method of
fragmentation based on photon absorption by a
precursor molecule. Photon absorption causes the
molecule to undergo an electronic transition to an
excited state followed by subsequent dissociation to
fragment species. UVPD produces abundant
fragments and is applicable to peptides, proteins, and
many other compound classes.
Thermo Scientific
2
(or MS/MS) scan with
scan with three stages of mass
Glossary: selected ion monitoring (SIM) scan type
Z
zoom scan type A scan type that provides information
about the charge state of one or more ions of interest.
Zoom scans are slower scans with higher resolution
than normal scans.
Orbitrap Tribrid Series Getting Started Guide 93