Thermo Scientific Orbitrap Fusion Lumos Getting Started Manual page 110

Glossary: nanoelectrospray ionization (nanoESI or NSI)
N
nanoelectrospray ionization (nanoESI or NSI) A
type of electrospray (ESI) that accommodates very
low flow rates of sample and solvent at 1–20 nL/min
(for static nanoelectrospray) or 100–1000 nL/min
(for dynamic nanoelectrospray, which is also called
nanoESI nanoLC gradient separation).
nanoESI (NSI) spray current The flow of charged
particles in the nanoESI (NSI) source. The voltage
on the NSI spray needle supplies the potential
required to ionize the particles.
nanoESI (NSI) spray voltage The high voltage that is
applied to the spray needle in the nanoESI (NSI)
source to produce the NSI spray current as liquid
emerges from the nozzle. The NSI spray voltage is
selected and set; the NSI spray current varies.
P
precursor ion An electrically charged molecular
species that can dissociate to form fragments. The
fragments can be electrically charged or neutral
species. A precursor ion can be a molecular ion or an
electrically charged fragment of a molecular ion.
precursor mass The mass-to-charge ratio of a
precursor ion. The location of the center of a target
precursor-ion peak in mass-to-charge ratio (m/z)
units.
product ion An electrically charged fragment of an
isolated precursor ion.
product mass The mass-to-charge ratio of a product
ion. The location of the center of a target production
peak in mass-to-charge ratio (m/z) units.
profile data Data representing mass spectral peaks as
point-to-point plots, with each point having an
associated intensity value.
Q
qualitative analysis Chemical analysis designed to
determine the identity of the components of a
substance.
92 Orbitrap Tribrid Series Getting Started Guide
quantitative analysis Chemical analysis designed to
determine the quantity or concentration of a specific
substance in a sample.
R
reagent carrier gas Ultra-high-purity nitrogen gas
used to transfer the reagent to the reagent ion source
that is regulated by the backpressure regulator.
relative standard deviation (RSD) A measure of the
dispersion of a group of measurements relative to the
mean of the group. Relative standard deviation is
expressed as a percentage of the average value. The
percent relative standard deviation is calculated as:
  S X  
%RSD = 100
where S is the standard deviation and
mean.
retention time (RT) The time after injection at which
a compound elutes. The total time that the
compound is retained on the chromatograph
column.
S
scan Comprised of one or more microscans. Each
microscan is one mass analysis (ion injection and
storage/scan-out of ions) followed by ion detection.
After the microscans are summed, the scan data is
sent to the data system for display, storage, or both.
The process of ramping the amplitude of the RF and
dc voltages on the multipole rods in the mass
analyzer to transmit ions from the lowest mass to the
highest mass of a specified scan range.
scan mode and scan type combinations A function
that coordinates the three processes in the MS
detector: ionization, mass analysis, and ion detection.
You can combine the various scan modes and scan
types to perform a wide variety of experiments.
scan power The scan power n in MS
the number of stages of mass analysis. For example, a
scan power of n = 1 corresponds to an MS
scan with one stage of mass analysis. A scan power of
X is the sample
n
, which expresses
1
(or MS)
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