Welch Allyn AED 10 User Manual page 85

76 Specifications
episodes). Three ED50 estimation procedures were run in parallel, with the device being
used alternated on each shock. After each of the three independent ED50 estimation
procedures had been completed, the entire protocol was repeated twice more, each time
starting all devices at an energy of 30 joules. The ED50 peak current and energy was then
estimated for each animal by logistic regression analysis. Individual phase durations and
overall pulse durations were measured and recorded on each shock.
Results
The study consisted of 344 total fibrillation/defibrillation episodes. The mean ED50 and
ID50 estimates (to one decimal place) are shown below. The significance of difference (p-
value) was calculated by the Wald test in each case, and is shown below. Also shown are
the mean total durations measured for each device.
Summary Table -ED50, ID50, & Duration
Mean
ID50 Peak Current (Amps)
Significance of difference (p-value)
ED50 Delivered Energy (Joules)
Significance of difference (p-value)
Total Duration (msec)
Conclusion
The MRL Orbital Biphasic waveform was as effective as the Biphasic 2kV waveform, and
more effective than the monophasic waveform. While both biphasic waveforms required
less peak current than the monophasic waveform, the MRL Orbital Biphasic waveform
required statistically less peak current than the 2 kV biphasic waveform defibrillator.
Welch Allyn AED 10 Automatic External Defibrillator
Monophasic Welch Allyn
Waveform AED 10
9.0 6.4
<0.001
(Welch Allyn AED 10
vs. Monophasic)
40.2 21.4
<0.001
(Welch Allyn AED 10
vs. Monophasic)
11.9 12.3
2kV Biphasic
Waveform
8.3
<0.001
(Welch Allyn AED 10
vs. 2kV Biphasic)
22.7
<0.4937
(Welch Allyn AED 10
vs. 2kV Biphasic)
13.1