Solvents Used Infrequently; Solvents Used Commonly As Diluents - Waters ACQUITY QDa Overview And Maintenance Manual

Table C–2:
Solution
Ammonium hydroxide
Ammonium formate
Ammonium acetate
Ammonium bicarbonate
Tetrahydrofuran (THF)
C.3.3

Solvents used infrequently

The following reagents are used less frequently with electrospray ionization than those listed in the
previous table, because they decrease sensitivity. Nevertheless, they are often required for
suitable chromatographic resolution.
Note: At the concentrations specified below, the reagents are not expected to adversely affect the
performance of the materials shown in the list of items exposed to solvents on
you must keep concentrations to the lowest levels that maintain chromatographic resolution.
Table C–3:
Solution
Diethylamine (DEA)
Triethylamine (TEA)
Hexafluoroisopropanol (HFIP)
Hexyl Ammonium Acetate
C.3.4

Solvents used commonly as diluents

The following solvents, often used as sample diluents, are not expected to adversely affect the
performance of the materials shown in the list of items exposed to solvents on
Table C–4:
Solution
Toluene
Methyl tert-butyl ether (MTBE)
Hexane
Dichloromethane
Dimethylformamide (DMF)
Dimethyl sulfoxide (DMSO)
Heptane
Solvents used to prepare mobile phases (KAD) (Continued)
Solvents used infrequently
Solvents used commonly as diluents
June 28, 2016, 715003956 Rev. C
Concentration
≤1%
≤50 mM
≤50 mM
≤50 mM
≤15%
Concentration
≤
0.5%
≤
0.5%
≤
5%
≤
50 mM
Concentration
≤
5%
≤
5%
≤
5%
≤
2%
≤
5%
≤
5%
≤
5%
Page 74
page 72. However,
page 72.