Chapter 1: ImageXpress Pico Automated Cell Imaging System
Sample (X-Y) Stage
Plate Holder
The plate holder is designed for scanning multi-well microplates in standard ANSI (SBS)
formats with plastic or glass bottoms. It can accommodate other plate formats that have
standard microplate footprint dimensions. For example, glass slides can be imaged using a
slide adapter included in the accessory kit. Optimal image quality depends on plate flatness,
well bottom thickness, and optical clarity.
A spring-loaded, mechanical clamp holds the sample plate securely in the plate holder. The
clamp automatically opens when the sample (X-Y) stage moves to the load/eject position; it
automatically closes when the sample (X-Y) stage moves the plate into position for imaging.
Slide Holder
The slide holder holds four standard microscope slides of 25 mm x 75 mm (1 in. x 3 in.).
LED Autofocus
The ImageXpress Pico System uses a high-powered LED to autofocus the sample. For higher
magnifications, you can select an additional image-based autofocus.
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