Christ Alpha 3-4 LSCbasic Operating Manual
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Christ Alpha 3-4 LSCbasic Operating Manual

Freeze-dryer
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Translation of the original operating manuel
sb-pe
Rev. 1.2 of 05/03/2019
Alpha 3-4 LSCbasic; ;
Version 11/2018
Alpha 3-4 LSCbasic
Part no. 102394, 102395
Freeze-dryer
Operating Manual
Please retain for later use!

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  • Page 1 Translation of the original operating manuel sb-pe Rev. 1.2 of 05/03/2019 Alpha 3-4 LSCbasic; ; Version 11/2018 Alpha 3-4 LSCbasic Part no. 102394, 102395 Freeze-dryer Operating Manual Please retain for later use!
  • Page 2 Freeze-dryer Alpha 3-4 LSCbasic Version 11/2018, Rev. 1.2 of 05/03/2019 • sb-pe 2 / 97 Translation of the original operating manuel...
  • Page 3 Freeze-dryer Alpha 3-4 LSCbasic In case of inquiries, please state the following numbers: Order number: Serial number: © Copyright by Martin Christ Gefriertrocknungsanlagen GmbH An der Unteren Söse 50 37520 Osterode am Harz Germany Tel.: +49 (0) 5522 / 5007-0...
  • Page 4 Freeze-dryer Alpha 3-4 LSCbasic Version 11/2018, Rev. 1.2 of 05/03/2019 • sb-pe 4 / 97 Translation of the original operating manuel...

  • Page 5: Table Of Contents

    Freeze-dryer Alpha 3-4 LSCbasic Table of contents General information ......................9 Importance of the operating manual .................. 9 Intended use ........................9 Warranty and liability....................... 10 Copyright ........................10 Explanation of symbols ....................10 Standards and regulations ....................10 Scope of supply ......................11 Layout and mode of operation ..................
  • Page 6 Freeze-dryer Alpha 3-4 LSCbasic Table of contents Safety devices ........................ 28 3.8.1 System check ......................28 3.8.2 Earth conductor check ....................28 Procedures in the event of hazards and accidents ............29 3.10 Maintenance and cleaning of the freeze-dryer ..............29 3.11...
  • Page 7 Freeze-dryer Alpha 3-4 LSCbasic Table of contents Malfunctions and error correction ..................69 General malfunctions ...................... 69 7.1.1 Power failure ......................70 7.1.2 Insufficient vacuum ....................71 7.1.2.1 Small flange connections ................... 71 7.1.2.2 Aeration valve, media drain valve ..............72 7.1.2.3...
  • Page 8 Freeze-dryer Alpha 3-4 LSCbasic Table of contents Version 11/2018, Rev. 1.2 of 05/03/2019 • sb-pe 8 / 97 Translation of the original operating manuel...

  • Page 9: General Information

    Any other use beyond this area of application is regarded as improper use. Martin Christ Gefriertrocknungsanlagen GmbH cannot be held liable for any damage resulting from such improper use. The following operations are regarded as NOT PERMISSIBLE: •...

  • Page 10: Warranty And Liability

     Copyright The copyright concerning the operating manual remains with Martin Christ Gefriertrocknungsanlagen GmbH. The operating manual is solely intended for the operator and their personnel. It includes instructions and information that may not be •...

  • Page 11: Scope Of Supply

    Freeze-dryer Alpha 3-4 LSCbasic 1 General information  Scope of supply Solvent package for round bottles (part no. 102394) includes: Name Part number Freeze-dryer Alpha 3-4 LSCbasic 102372 Capacitive vacuum sensor 125491 Vacuum pump RC6 125295 Corrugated hose, stainless steel...

  • Page 12: Layout And Mode Of Operation

    Freeze-dryer Alpha 3-4 LSCbasic 2 Layout and mode of operation  Layout and mode of operation  Layout of the freeze-dryer  2.1.1 Functional and operating elements 1 Ice condenser chamber 2 LSCbasic user (see chapter 6.4.1 - "User interface") 3...
  • Page 13 Freeze-dryer Alpha 3-4 LSCbasic 2 Layout and mode of operation 7 Aeration valve 8 Media drain valve Fig. 3: Left side of the freeze-dryer 9 Touchpanel Fig. 4: User interface with touchpanel Version 11/2018, Rev. 1.2 of 05/03/2019 • sb-pe...

  • Page 14: Name Plate

    Freeze-dryer Alpha 3-4 LSCbasic 2 Layout and mode of operation 10 Heat exchanger of the refrigeration unit 11 Name plate (see chapter 2.1.2 - "Name plate") 12 Vacuum connection 13 Serial interface 14 Electrical connection of the vacuum sensor 15 Connection of the vacuum sensor 16...

  • Page 15: Mode Of Operation

    Freeze-dryer Alpha 3-4 LSCbasic 2 Layout and mode of operation  Mode of operation  2.2.1 General information on freeze-drying What is freeze-drying? Freeze-drying or lyophilisation is a procedure for the gentle drying of high- quality products. The product is dried by  sublimation without passing through the liquid phase.
  • Page 16 Freeze-dryer Alpha 3-4 LSCbasic 2 Layout and mode of operation Fig. 7: Vapour pressure curve for ice and water (Sublimationsdruckkurve From a physical point of view, the freeze-drying process covers three phases (see figure below): (1) Freezing: The product to be dried is frozen under atmospheric pressure.
  • Page 17 Freeze-dryer Alpha 3-4 LSCbasic 2 Layout and mode of operation Fig. 8: Freeze-drying phases Please find further information about basic principles, optimum procedures and applications in the brochure "Smart freeze-drying", which can be downloaded at www.martinchrist.de  [Applications]  [Lyophilisation].

  • Page 18: Freeze-Drying Process

    Freeze-dryer Alpha 3-4 LSCbasic 2 Layout and mode of operation  2.2.2 Freeze-drying process The main components of a freeze-dryer are: • vacuum drying chamber or drying manifold, • vacuum pump for generating a vacuum inside the drying chamber, •...

  • Page 19: Main Drying

    Freeze-dryer Alpha 3-4 LSCbasic 2 Layout and mode of operation 2.2.2.3 Main drying When the product is frozen, the main drying phase commences. The vacuum pump is switched on. The pressure inside the drying chamber will be lowered to the value that corresponds to the freezing temperature in accordance with the vapour pressure curve for ice and water (sublimation pressure curve).

  • Page 20: Defrosting

    Freeze-dryer Alpha 3-4 LSCbasic 2 Layout and mode of operation 2.2.2.6 Defrosting Defrosting with hot gas As standard, the freeze-dryer is equipped with a hot-gas defrosting system. In order to defrost the ice condenser, heated refrigerant is fed through the heating coil.

  • Page 21: Safety

    Freeze-dryer Alpha 3-4 LSCbasic 3 Safety  Safety  Marking of the unit The following symbols are used for Christ freeze-dryers: Dangerous voltage On (Power) Hot surface Off (Power) Name plate (see chapter Caution! Risk of bruising 2.1.2 - "Name plate")

  • Page 22: Explanation Of The Symbols And Notes

    Freeze-dryer Alpha 3-4 LSCbasic 3 Safety  Explanation of the symbols and notes This operating manual uses the following names and symbols to indicate hazards: This symbol stands for a direct hazard to the life and health of persons. Non-observance of these symbols causes serious health problems up to life-endangering injuries.

  • Page 23: Responsibility Of The Operator

    Freeze-dryer Alpha 3-4 LSCbasic 3 Safety Responsibility of the operator The operator is obliged to ensure that the persons working on/with the freeze-dryer • are 18 years old or older, • have been specifically ordered to do so by the operator/owner and that...

  • Page 24: Operating Personnel

    Freeze-dryer Alpha 3-4 LSCbasic 3 Safety the material (stainless steel 1.4404 and 1.4435, borosilicate glass, EPDM, PVDF, ceramic AI and PTFE) or decrease the mechanical strength is prohibited. • The system must be maintained at regular intervals (see chapter 8 - "Maintenance and service").

  • Page 25: Safety Notes Concerning The Transport, Set-Up And Connection And Initial Start-Up Of The Freeze-Dryer

    Freeze-dryer Alpha 3-4 LSCbasic 3 Safety Safety notes concerning the transport, set-up and connection and initial start-up of the freeze-dryer The following notes and instructions must be observed in order to protect all persons and property. 3.6.1 General hazards General risk of injury...

  • Page 26: Hazards Caused By Improper Connection

    Freeze-dryer Alpha 3-4 LSCbasic 3 Safety 3.6.4 Hazards caused by improper connection Risk of injury caused by consequences of improper connection Improper connection may lead to a hazardous electrical incident at a later time during the operation of the freeze-dryer.

  • Page 27: Hazards Caused By The Refrigeration System (Natural, Flammable Refrigerants)

    DANGER Freeze-drying of products containing acids is only permissible if special protective measures and equipment-related precautions are taken! Consultation of Martin Christ Gefriertrocknungsanlagen GmbH is abso- lutely mandatory in order to define the measures that need to be taken! •...

  • Page 28: Hazards Caused By Contaminated Condensate (Defrosting Water)

    Freeze-dryer Alpha 3-4 LSCbasic 3 Safety 3.7.5 Hazards caused by contaminated condensate (defrosting water) Risk of poisoning/infection caused by contaminated condensate (defrosting water) The condensate may contain harmful substances originating from the product. WARNING Contact with the condensate may cause severe damage to health.

  • Page 29: Procedures In The Event Of Hazards And Accidents

    Freeze-dryer Alpha 3-4 LSCbasic 3 Safety  Procedures in the event of hazards and accidents Hazardous electrical incident: • Set the control switch to the "0" position in order to interrupt the power supply completely. Fire: • A fire in the electrical control system must be extinguished with a CO fire extinguisher! •...

  • Page 30: Measures To Be Taken To Ensure Safe Operation Of The Freeze-Dryer

    • Stop the freeze-dryer immediately in the event of a malfunction. Eliminate the malfunction (see chapter 7 - "Malfunctions and error correction") or contact the after-sales service of Firma Martin Christ Gefriertrocknungsanlagen GmbH (see chapter 7.3 - "Service contact"). •...

  • Page 31: Remaining Hazards

    3 Safety 3.12 Remaining hazards All Christ freeze-dryers were built state-of-the-art and according to the accepted safety rules. Danger to life and limb of the operator, or of third parties, or impairments of the units or other material assets, however, cannot be completely excluded when the units are being used.

  • Page 32: Storage And Transport

    Freeze-dryer Alpha 3-4 LSCbasic 4 Storage and transport  Storage and transport  Dimensions and weight Values for the freeze-dryer without a vacuum pump: Alpha 3-4 LSCbasic Height: 415 mm Width: 780 mm Depth: 555 mm + 80 mm vacuum connection Weight: approx.

  • Page 33: Notes On Transport

    Do not grab the unit at the plastic control panel (see figures below). correct incorrect Fig. 9: Lifting the freeze-dryer The freeze-dryer Alpha 3-4 LSCbasic weighs approx. 86 kg! CAUTION The centre of gravity of the freeze-dryer is off-centre! CAUTION •...

  • Page 34: Packaging

    Lift the freeze-dryer upwards and out of the crate/cardboard box. When lifting the unit, always reach under the freeze-dryer from the side. The freeze-dryer Alpha 3-4 LSCbasic weighs approx. 86 kg! CAUTION The centre of gravity of the freeze-dryer is off-centre! CAUTION •...

  • Page 35: Set-Up And Connection

    Freeze-dryer Alpha 3-4 LSCbasic 5 Set-up and connection  Set-up and connection  Location of use Use the freeze-dryer solely in closed and dry spaces. Refrigeration problems of the freeze-dryer are often caused by insufficient conditions at the location of use. This is why compliance with the following...

  • Page 36: Power Supply

    DANGER Christ freeze-dryers are units of protection class I. The freeze-dryers of the type Alpha 3-4 LSCbasic have a three-wire power cord with an IEC C13 connector (see chapter 10 - "Technical data"). An equipotential bonding screw is located on the back below the mains power input (see chapter 2.1.1 - "Functional and operating elements").

  • Page 37: Media Drain Valve

    Freeze-dryer Alpha 3-4 LSCbasic 5 Set-up and connection  Media drain valve The media drain valve is located at the bottom of the left side of the unit (see chapter 2.1.1 - "Functional and operating elements"). It is used to drain off the condensate and the defrosting water.
  • Page 38 Freeze-dryer Alpha 3-4 LSCbasic 5 Set-up and connection It is absolutely essential to comply with the manufacturer’s instructions in the separate operating manual of the vacuum sensor! NOTE Pfeiffer CMR 363 (capacitive) Fig. 12: Vacuum sensor The vacuum sensor comes supplied in a calibrated state.

  • Page 39: Vacuum Pump

    Freeze-dryer Alpha 3-4 LSCbasic 5 Set-up and connection 5.4.6 Vac uum pump  Vacuum pump It is absolutely essential to refer to the separate instruction manual of the vacuum pump and exhaust filter (if applicable)! NOTE The vacuum pump must be connected to the vacuum connection of the unit and to the electrical socket at the back of the unit, which is marked accordingly (see chapter 2.1.1 - "Functional and operating elements").

  • Page 40: Pressure Control Valve

    Freeze-dryer Alpha 3-4 LSCbasic 5 Set-up and connection  Pressure control valve The pressure control valve is integrated in the suction pipe between the vacuum pump and ice condenser chamber. During certain, specified process phases, it interrupts the volume flow to the vacuum pump (see chapter 2.2.1 - "General information on freeze-drying")

  • Page 41: Installation Of The Accessories

    (stainless steel) Glass cover 6 Vacuum sensor 7 Manifold 8 Rubber valve Fig. 15: Freeze-dryer Alpha 3-4 LSCbasic with solvent package for round bottles Version 11/2018, Rev. 1.2 of 05/03/2019 • sb-pe 41 / 97 Translation of the original operating manuel...

  • Page 42: Rubber Valves

    10 Connecting ring with rubber valves 11 Glass cover Fig. 16: Freeze-dryer Alpha 3-4 LSCbasic with solvent package  5.8.1 Rubber valves The rubber valves enable the connection of round-bottom flasks, wide-neck filter bottles, or distributors for ampoules to a manifold or drying chamber.
  • Page 43 Freeze-dryer Alpha 3-4 LSCbasic 5 Set-up and connection The rubber valves come supplied in an ungreased state. This is why a thin layer of vacuum grease must be applied to the connector of the freeze- dryer as well as to the vessel connector prior to start-up in order to ensure trouble-free operation.

  • Page 44: Operation

    Freeze-dryer Alpha 3-4 LSCbasic 6 Operation Operation Initial start-up Before the initial start-up, please ensure that your freeze-dryer is properly set up and installed (see chapter 5 - "Set-up and connection") WARNING Preparation The ice condenser chamber must be clean and dry.

  • Page 45: Lscbasic Control System

    Freeze-dryer Alpha 3-4 LSCbasic 6 Operation LSCbasic control system The control system LSCbasic (Lyo Screen Control basic) was specifically developed for the control of freeze-drying processes. The clear user interface enables the intuitive operation of the unit. Fig. 19: Start screen of the LSCbasic control unit (example) 6.4.1...

  • Page 46: Main Window "Process

    Freeze-dryer Alpha 3-4 LSCbasic 6 Operation The user interface is divided into three main windows that can be called up by touching the corresponding buttons: Process This window is also the standard user interface. It is used to control the freeze-drying process manually.
  • Page 47 Freeze-dryer Alpha 3-4 LSCbasic 6 Operation No USB storage device or LAN network connected symbol USB storage device connected Active process recording on a USB storage device Network available, but no network drive connected Network drive connected (e.g. LyoLogplus) Network drive connected and active process recording Button "Schematic system diagram"...
  • Page 48 Freeze-dryer Alpha 3-4 LSCbasic 6 Operation Fig. 23: Dialogue box "Select actual value" • Select the desired configuration or exit the dialogue box by pressing the "return" button. In this way, it is possible to configure a personalised overview of the actual values.
  • Page 49 In the event of an error or message, the window “Process and equipment messages” will open automatically. In addition, a sound signal is emitted until the error is acknowledged. Not available for Alpha 3-4 LSCbasic Version 11/2018, Rev. 1.2 of 05/03/2019 • sb-pe 49 / 97...
  • Page 50 Freeze-dryer Alpha 3-4 LSCbasic 6 Operation There are three categories of faults: • Red: error messages • Orange: process messages • Yellow: general messages The representation of the message provides information about its current status. A double frame around a message means that the error has not been eliminated yet.
  • Page 51 Freeze-dryer Alpha 3-4 LSCbasic 6 Operation Use the arrow buttons to open the individual windows. The error message text is always followed by an error code. Always indicate the error code in the event of enquiries or service requests! NOTE 4...
  • Page 52 Freeze-dryer Alpha 3-4 LSCbasic 6 Operation Button "Standard unit test" Apart from the process phases of the freeze-drying process ("Freezing", "Warm-up", "Main drying" and "Final drying") and the operating mode "Defrosting", the button "Standard unit test" is also available. This button opens a selection of tests with fixed parameters.
  • Page 53 • Select "Leakage test" and start the test via the "Run" button. The parameters for the leakage test have been developed by Martin Christ Gefriertrocknungsanlagen specifically for the freeze-dryers. In a first step, these parameters (vacuum, ice condenser temperature) must be reached.
  • Page 54 Freeze-dryer Alpha 3-4 LSCbasic 6 Operation Button "Stop" (8) Pressing this button stops the current process. The freeze-dryer switches to standby. Version 11/2018, Rev. 1.2 of 05/03/2019 • sb-pe 54 / 97 Translation of the original operating manuel...

  • Page 55: Main Window "Options

    Freeze-dryer Alpha 3-4 LSCbasic 6 Operation 6.4.1.2 Main window "Options" The main window "Options" is where the basic configuration of the control system is defined. It enables the optimum adaptation of the freeze-dryer to its specific area of application. General "General"...
  • Page 56 CHRIST LyoCube (a rectangular drying chamber that can be loaded from the front) Not available for Alpha 3-4 LSCbasic. Not available for Alpha 3-4 LSCbasic. Version 11/2018, Rev. 1.2 of 05/03/2019 • sb-pe 56 / 97...
  • Page 57 Freeze-dryer Alpha 3-4 LSCbasic 6 Operation Fig. 35: Dialogue box "Freeze-drying process" Administration "Administration" options: 1 "Date/Time" "Network" "System properties" "Access protection" "Device options" Fig. 36: Dialogue box "Options" / "Administration" Version 11/2018, Rev. 1.2 of 05/03/2019 • sb-pe 57 / 97...
  • Page 58 Freeze-dryer Alpha 3-4 LSCbasic 6 Operation Date/Time (1) The control system is equipped with an integrated, battery-buffered clock. After a failure of the buffer battery, the date and time must be reset. Fig. 37: Dialogue box “Change date/time Network (2) This dialogue box is used to change the network settings.
  • Page 59 Freeze-dryer Alpha 3-4 LSCbasic 6 Operation Fig. 39: Dialogue box "System properties" Beeper: The beeper sounds in the event of a malfunction, for example. • If the setting is "On", the beeper sounds at intervals of a few seconds until the message is acknowledged.
  • Page 60 Freeze-dryer Alpha 3-4 LSCbasic 6 Operation Access protection (4) In this dialogue box, the access rights can be managed on several levels and they can be protected with a password. In the factory setting with activated access protection, data can be viewed but not edited.
  • Page 61 • Select the button "Add option". An input window opens. • Enter the six-digit CHRIST activation code that was supplied for this option. Note that the code is case-sensitive. Options can be removed in the same way. The changes will not become effective until after a restart of the freeze- dryer.
  • Page 62 Freeze-dryer Alpha 3-4 LSCbasic 6 Operation Service "Service" options: 1 "Operating hours" "Failure memory" "Vacuum pump oil change" "Maintenance" "Sensor adjustment" Fig. 44: Dialogue box "Service" (varies depending on the type of freeze-dryer) Operating hours (1) This dialogue box is used to view the number of operating hours of the various components of the freeze-dryer, e.g.
  • Page 63 Freeze-dryer Alpha 3-4 LSCbasic 6 Operation Always indicate the error code in the event of enquiries or service requests! NOTE Fig. 46: Dialogue box "Failure memory" Vacuum pump oil change (3) The system monitors the oil change interval of the vacuum pump. The interval can be adapted to the vacuum pump model and utilisation.
  • Page 64 Freeze-dryer Alpha 3-4 LSCbasic 6 Operation Maintenance (4) The maintenance interval of the freeze-dryer is set at 3,000 operating hours or at least one maintenance per year. When the end of a maintenance interval is reached, a corresponding message will be displayed.

  • Page 65: Main Window

    Freeze-dryer Alpha 3-4 LSCbasic 6 Operation 6.4.1.3 Main window "?" This main window includes the most important information concerning your freeze-dryer: Freeze-dryer type Control system type Serial number Manufacturer contact data Details concerning the software version Fig. 49: Freeze-dryer system information (example) In the event of enquiries at the manufacturer, please state the data that is stated here.

  • Page 66: Entering Set Values

    Freeze-dryer Alpha 3-4 LSCbasic 6 Operation If the value "∞" (infinite) is selected for a process phase, the next phase must be started manually via the button "Operating mode: select/start". NOTE The set values of the active phase can be changed during the process run.
  • Page 67 Freeze-dryer Alpha 3-4 LSCbasic 6 Operation "Defrosting" button 2 "Leakage test" button (option) Fig. 51: Dialogue box "Set values: view/edit" Fields that are displayed in the form of buttons can be edited. • Defrosting (1) This button is used to pre-define the defrosting time and temperature.

  • Page 68: Optional Extensions

    Since absolutely tight components simply do not exist, a leak rate is determined. The parameters for the leakage test have been developed by Martin Christ Gefrier- trocknungsanlagen specifically for freeze-dryers. In a first step, these parameters (vacuum, ice condenser temperature) must be reached.

  • Page 69: Malfunctions And Error Correction

    Freeze-dryer Alpha 3-4 LSCbasic 7 Malfunctions and error correction  Malfunctions and error correction Malfunctions are displayed in the dialogue box "Process & equipment messages" (see chapter 7.2 - "Process and error messages"). An acoustic signal sounds when an error message is generated.

  • Page 70: Power Failure

    Acknowledge the message. If the message is displayed repeatedly, inform the service department (see chapter 7.3 - "Service contact") If it is impossible to eliminate the errors, contact the Christ service department! NOTE  7.1.1 Power failure The control system continues with the process after a power failure.

  • Page 71: Insufficient Vacuum

    Freeze-dryer Alpha 3-4 LSCbasic 7 Malfunctions and error correction  7.1.2 Insufficient vacuum The vacuum checks must be carried out when the ice condenser is frozen. NOTE  7.1.2.1 Small flange connections Leakages are often due to improper small flange connections between the various components and hose connections or to leakages in the valves.

  • Page 72: Aeration Valve, Media Drain Valve

    Freeze-dryer Alpha 3-4 LSCbasic 7 Malfunctions and error correction  7.1.2.2 Aeration valve, media drain valve A malfunction of the aeration valve or the media drain valve may have several causes. One potential source are contaminants such as product residues within the valve.

  • Page 73: Insufficient Ice Condenser Temperature

    Freeze-dryer Alpha 3-4 LSCbasic 7 Malfunctions and error correction  7.1.3 Insufficient ice condenser temperature Ensure sufficient ventilation. Do not place any paper, cloth, or similar material behind or under the unit, since otherwise the air circulation will be impaired.

  • Page 74: Service Contact

    Freeze-dryer Alpha 3-4 LSCbasic 7 Malfunctions and error correction  Service contact In the event of queries, malfunctions, or spare part enquiries: From Germany: Contact Martin Christ Gefriertrocknungsanlagen GmbH An der Unteren Söse 50 37520 Osterode (Germany) Tel. +49 (0) 55 22 / 50 07-44 44 E-mail: support.lab@martinchrist.de...

  • Page 75: Maintenance And Service

    Freeze-dryer Alpha 3-4 LSCbasic 8 Maintenance and service  Maintenance and service The freeze-dryer and the accessories are subject to high mechanical stress. Thorough maintenance performed by the user extends the service life and prevents premature failure. If corrosion or other damage occurs due to improper care, the manufacturercannot be held liable or subject to any warranty claims.

  • Page 76: Ice Condenser Chamber

    Freeze-dryer Alpha 3-4 LSCbasic 8 Maintenance and service Cleaning of the freeze-dryer • Switch the freeze-dryer off by actuating the mains power switch and disconnect the power cord from the wall outlet before cleaning. • If the freeze-dryer has been contaminated with toxic, radioactive, or...

  • Page 77: Heat Exchanger (Only For Air-Cooled Freeze-Dryers)

    Check the heat exchanger at least once per month for soiling and clean it if necessary. • Please contact the Christ service department if you have any queries (see chapter 7.3 - "Service contact"). Version 11/2018, Rev. 1.2 of 05/03/2019 • sb-pe...

  • Page 78: Vacuum Pump

    The other oil changes depend on the operating conditions. In general, an interval of 500 to 1,000 operating hours is sufficient. • Please contact the Christ service department if you have any queries (see chapter 7.3 - "Service contact"). ...

  • Page 79: Vacuum Sensor

    • Clean the accessories outside the freeze-dryer once a week or preferably after each use. • Use only the accessories that have been specified by Martin Christ Gefriertrocknungsanlagen GmbH.  Version 11/2018, Rev. 1.2 of 05/03/2019 • sb-pe 79 / 97...

  • Page 80: Disinfection Of The Drying Chamber And Accessories

    Freeze-dryer Alpha 3-4 LSCbasic 8 Maintenance and service Disinfection of the drying chamber and accessories  • Use commercially-available disinfectants such as, for example, Incidur     Meliseptol , Sagrotan , Buraton , or Terralin (available at specialised trade).

  • Page 81: Return Of Defective Parts

    Freeze-dryer Alpha 3-4 LSCbasic 8 Maintenance and service  Return of defective parts Although we exercise great care during the production of our products, it may be necessary to return a unit or accessory to the manufacturer. In order to ensure the quick and economical processing of returns of...

  • Page 82: Disposal

    Freeze-dryer Alpha 3-4 LSCbasic 9 Disposal  Disposal  Disposal of the freeze-dryer Martin Christ Gefriertrocknungsanlagen GmbH is a registered manufacturer of electric and electronic devices that are solely intended for commercial use. • Comply with all local rules and regulations. ...

  • Page 83: 10 Technical Data

    Freeze-dryer Alpha 3-4 LSCbasic 10 Technical data  10 Technical data Manufacturer Martin Christ Gefriertrocknungsanlagen GmbH An der Unteren Söse 50 37520 Osterode (Germany) Type Alpha 3-4 LSCbasic Part number 102394, 102395 Performance data Ice condenser - capacity 4 kg max - performance 2.5 kg / 24 h max...

  • Page 84: Ambient Conditions

    Freeze-dryer Alpha 3-4 LSCbasic 10 Technical data Equipment connections Vacuum connection Small flange connection DN25KF (ISO 28403, DIN 2861) Media drain valve Hose nozzle DN10 (outside diameter 12 mm) Aeration valve Hose nozzle DN6 (outside diameter 10 mm max.) Vacuum sensor...

  • Page 85: 11 Appendix

    Freeze-dryer Alpha 3-4 LSCbasic 11 Appendix  11 Appendix  11.1 EC declaration of conformity in accordance with the EC Machinery Directive Version 11/2018, Rev. 1.2 of 05/03/2019 • sb-pe 85 / 97 Translation of the original operating manuel...
  • Page 86 Freeze-dryer Alpha 3-4 LSCbasic 11 Appendix Version 11/2018, Rev. 1.2 of 05/03/2019 • sb-pe 86 / 97 Translation of the original operating manuel...

  • Page 87: Declaration Of Conformity - China Rohs 2

    Freeze-dryer Alpha 3-4 LSCbasic 11 Appendix Declaration of conformity – China RoHS 2 11.2 Version 11/2018, Rev. 1.2 of 05/03/2019 • sb-pe 87 / 97 Translation of the original operating manuel...
  • Page 88 Freeze-dryer Alpha 3-4 LSCbasic 11 Appendix Version 11/2018, Rev. 1.2 of 05/03/2019 • sb-pe 88 / 97 Translation of the original operating manuel...

  • Page 89: Ec Declaration Of Conformity In Accordance With The Pressure Equipment Directive

    Freeze-dryer Alpha 3-4 LSCbasic 11 Appendix 11.3 EC declaration of conformity in accordance with the Pressure Equipment Directive Version 11/2018, Rev. 1.2 of 05/03/2019 • sb-pe 89 / 97 Translation of the original operating manuel...
  • Page 90 Freeze-dryer Alpha 3-4 LSCbasic 11 Appendix Version 11/2018, Rev. 1.2 of 05/03/2019 • sb-pe 90 / 97 Translation of the original operating manuel...

  • Page 91: 12 Glossary

    12 Glossary Cold trap operation Cold traps are used for the condensation of moisture or solvents in combination with vacuum pumps. CHRIST freeze-dryers can be used as cold traps. Desorption Desorption (from Latin de-sorbere, sorbere = sup up, suck in) describes a phenomenon whereby molecules are released from the surface of a solid.
  • Page 92 Freeze-dryer Alpha 3-4 LSCbasic 12 Glossary Single-chamber method (not available for freeze-dryers with an LSCbasic control system) With the single-chamber method, the freezing as well as the subsequent drying of the product take place inside the ice condenser chamber. The sample is frozen as a result of the low temperature of the ice condenser (-55°C in the case of single-stage systems or -85°C in the case of double-...

  • Page 93: 13 Index

    Freeze-dryer Alpha 3-4 LSCbasic Index 13 Index Connection requirements ......83 Contaminated condensate (hazards) ..28 Access protection........60 Contaminated defrosting water (hazards) .. 28 Accessories ......... 30, 79 Control system type ........65 Accessories (installation) ......41 Cooling system .......... 84 Accident prevention ........
  • Page 94 Freeze-dryer Alpha 3-4 LSCbasic Index Double-chamber method ...... 56, 91 Hazards (contaminated defrosting water) ... 28 Double-chamber method LyoCube (outside) Hazards (electricity) ........26 ............... 56 Hazards (general, transport to commissioning) ........25 Hazards (products, harmful) ....... 27 Earth conductor check ....... 28 Hazards (refrigeration system) ....
  • Page 95 Freeze-dryer Alpha 3-4 LSCbasic Index Operator/maintenance/administrator password ..........61 Main drying ..........19 Option: Leakage test ........53 Main window "?" ......... 65 Option: USB process recording ....49 Main window "Options" ......55 Optional extensions ........68 Main window "Process" ......46 Mains fuse ..........
  • Page 96 Freeze-dryer Alpha 3-4 LSCbasic Index Surfaces, hot (hazards) ......28 Switching the freeze-dryer OFF ....68 Safety and hazard notes ......24 Switching the freeze-dryer on..... 44 Safety data sheets ........84 System check ..........28 Safety devices ........... 28 System properties ........
  • Page 97 Freeze-dryer Alpha 3-4 LSCbasic Index Warranty and liability ........10 Water cooling system ......... 84 Year of manufacture ........14 Weight ..........32, 83 Version 11/2018, Rev. 1.2 of 05/03/2019 • sb-pe 97 / 97 Translation of the original operating manuel...

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