Routine Tasks; Cleaning The Spray Chamber - Daily - Agilent Technologies Triple Quadrupole LC/MS User Manual

5 Maintenance

Routine Tasks

Routine Tasks

Cleaning the spray chamber - daily

Perform this maintenance daily or at the end of each shift or anytime you suspect
carryover contamination from one sample or analysis to another.
Use the weekly cleaning procedure if symptoms of contamination persist or if the
NOTE
spray shield or capillary cap show significant discoloration that cannot be
removed by the regular, daily cleaning.
Tools needed:
• Clean, powder-free nitrile gloves
• Clean lint-free cloth
• LC/MS-grade isopropanol
• LC/MS-grade water
• Clean wash bottle
To perform daily cleaning of the spray chamber,
1 Put on clean powder-free nitrile gloves.
2 Lower the drying gas temperature to the minimum level.
3 For APCI/multimode, lower the vaporizer heater temperature to the minimum
level.
Make sure the source is cooled before you clean the spray shield.
WAR NIN G
4 In a clean wash bottle, prepare a 50:50 mix of LC/MS-grade isopropanol and
LC/MS-grade water.
5 Open the spray chamber.
6 Dampen a clean lint-free cloth with a mixture of LC/MS-grade isopropanol and
LC/MS-grade water.
7 Wipe the spray shield and the area around the spray shield.
8 Close the spray chamber.
91 Agilent Triple Quadrupole LC/MS System User Guide