Cleaning The Spray Chamber - Weekly - Agilent Technologies Triple Quadrupole LC/MS User Manual

5 Maintenance

Cleaning the spray chamber - weekly

5 Attach the calibrant bottle onto the fixed bottle cap. Turn the calibrant bottle
counterclockwise to tighten.
The bottle only needs to be snug. Do not over-tighten the bottle. A leaky bottle
C AU T I O N
cap can prevent the bottle from pressurizing and can lead to the evaporation of
the contents.
The tuning mixes are not interchangeable. Failure to change the tuning mix
C AU T I O N
when the source or inlet assembly is changed can result in miscalibration of
the instrument and errors in mass assignments.

Cleaning the spray chamber - weekly

Perform this maintenance weekly or whenever symptoms indicate that
contamination exists in the spray chamber and normal daily cleaning does not
correct the problem.
Tools needed:
• Clean powder-free nitrile gloves
• Clean lint-free cloth
• LC/MS-grade isopropanol
• LC/MS-grade water
• Clean wash bottle
• 4000 grit abrasive paper
To perform weekly cleaning of the spray chamber,
1 Put on clean powder-free nitrile gloves.
2 Disconnect the nebulizer sample line and sample nebulizer gas tubing from
the nebulizer.
3 Disconnect all cables and tubings from the instrument.
4 Open the latch of spray chamber.
5 Open the spray chamber.
6 Put the source under a fume hood.
93 Agilent Triple Quadrupole LC/MS System User Guide