Base-Soluble Contaminants Or Precipitates With The Dionex Crs 500 - Thermo Scientific Dionex Chemically Regenerated Suppressor 500 Series Product Manual

5 – Suppressor Cleanup

5.1 Base-Soluble Contaminants or Precipitates with the Dionex CRS 500

A. Disconnect the analytical (and guard) column(s) from the injection valve and the
B. Turn off the regenerant and disconnect the regenerant line from the Dionex CRS 500
C. Disconnect the liquid line from the Dionex CRS 500 ELUENT OUT port to the cell at
D. Pump a solution of 0.1 M NaOH through the Dionex CRS 500 eluent chamber at 1 – 2
! Bypassing internal pump manifolds when temporarily pumping high concentration
cleaning solutions significantly reduces the time required to re-equilibrate the system to
low concentration eluents.
NOTE
E. Flush the columns and the Dionex CRS 500 separately with deionized water, having a
F. Perform a QuickStart procedure as outlined in Section 3.2, "Start Up."
G. Install the Dionex CRS 500 unit back on the system and pump regenerant through the
H. Flush the Dionex CRS 500 with eluent for 10 minutes.
I.
Thermo Scientific
031727-07
Dionex CRS 500 Refer to the specific analytical column Product Manual for column
cleanup procedures.
REGEN IN port.
the cell and reconnect it to the REGEN IN port.
mL/min (4 mm) or 0.25 – 0.5 mL/min (2 mm). If using the eluent pump, connect a
temporary line from the priming block or the low-pressure tee of the pump to the
sodium hydroxide container to avoid contaminating the pump manifolds.
specific resistance of 18.2 megohm-cm, for 10 minutes.
regenerant chamber. Turn on the eluent after flushing the regenerant chamber. In the
DCR mode, turning on the eluent flow is needed to push the regenerant into the Dionex
CRS 500.
Reinstall the analytical (and guard) column(s). Begin pumping eluent through the
system at the flow rate required for your analysis and equilibrate the system.
Product Manual for Dionex CRS 500 Suppressor Page 39 of 40