Troubleshooting Guide; Small Analyte Peak Areas; High Background Conductivity - Thermo Scientific Dionex Chemically Regenerated Suppressor 500 Series Product Manual

4

– Troubleshooting Guide

4. Troubleshooting Guide
The purpose of the Troubleshooting Guide is to help you solve operating problems that may
arise while using the Dionex Chemically Regenerated Suppressor (Dionex CRS 500). For more
information on problems that originate with the Ion Chromatograph or the specific Anion
exchange column set in use, refer to the Troubleshooting Guide in the appropriate Installation
Manual. If you cannot solve the problem on your own, contact the Dionex Regional Office
nearest you (see, "Dionex Worldwide Offices").

4.1 Small Analyte Peak Areas

If small peak areas are observed when working with a pressurized reservoir
A. Stop the eluent flow while flowing regenerant flow into the suppressor for 5 minutes
B. If peak response has not recovered then perform quick start procedure as outlined in
C. In the DCR mode if the above problem is observed then follow instructions outlined in
D. If the correct peak areas are not observed following two injections of a standard test

4.2 High Background Conductivity

A. Check that the regenerant is flowing from the waste line at the proper flow rate.
Thermo Scientific
031727-07
APPENDIX A, "QuickStart for the External Chemical Mode and the AutoRegen
Mode."
APPENDIX B, "QuickStart for the Displacement Regenerant Mode."
solution, contact the nearest Thermo Scientific Regional Office (see, "Thermo
Scientific Worldwide Offices").
1. If there is no flow from the waste line, disconnect the 0.012" i.d. tubing connected
to the waste line. If the regenerant lines and the suppressor are filled with
regenerant and there are no restrictions in the regenerant line, the regenerant should
flow freely from the 1/8" o.d. waste line. If there is no flow, make sure the
reservoir cap is tight and that there are no audible air leaks. Also make sure that the
regenerant reservoir is pressurized. If it is, trace the regenerant lines backward
from the reservoir to find and remove any blockage.
2. If there is flow from the waste line, but it is less than the desired flow rate, increase
the flow rate by shortening the 0.012" i.d. waste line tubing or by increasing the
reservoir pressure. If the flow rate is correct, go on to the next step.
3. If the regenerant is flowing at the desired rate, either the selected regenerant flow
rate is too slow or the regenerant is too dilute to suppress the eluent concentration
at the set eluent flow rate. Refer to Tables 3 or 4, "Matching Regenerant
Concentration and Flow Rate to Eluent Concentration and Flow Rate," for the
Dionex ACRS 500 or to Tables 5 and 6, "Practical Maximum Eluent Concentration
Suppression Guidelines," for the Dionex CCRS 500 and then increase the
regenerant flow rate or increase the regenerant concentration.
Product Manual for Dionex CRS 500 Suppressor Page 34 of 40