Conclusion; References - Zeiss CIRRUS HD-OCT 500 User Manual

B-8
2660021169012 Rev. A 2017-12
Appendix
Table B-7: Rate of failure of the Fovea Finding Algorithm by Disease Category
N
AMD 77
DR 51
VRI 44
Other 62
ME 41
No disease 44

Conclusion

CIRRUS HD-OCT retinal thickness measurements are accurate and repeatable. Better than
85% of all scans are correctly segmented, even in the presence of pathology. Features
introduced with CIRRUS 4.0 software improve repeatability standard deviation to 2.5 μm in
normals and to better than 9 μm for subjects with a variety of pathologies.

References

1. M. Weisbrod, P. Stetson, M. Wieland, N. Bressler, U. Schmidt–Erfurth, R. Knighton.
G. Gregori, "Comparison of Hand–Drawn ILM and RPE Segmentation to the Retinal Segmentation Algorithm of the
CIRRUS HD-OCT," ARVO 2008, poster 4240.
2. M. Chang, M. Durbin, M. Weiland, U. Schmidt–Erfurth, G. Gregori, N. Bressler, "Repeatability of retinal thickness
measurements using CIRRUS HD-OCT Spectral Domain Technology," ARVO 2008, poster 4253.
3. W. Geitzenauer, C. Kiss, M. Durbin, T. Abunto, M. Wieland, N. Bressler, G. Gregori,
U. Schmidt–Erfurth, "Comparing Retinal Thickness Measurements From CIRRUS Spectral–Domain and Stratus Time–
Domain OCT," ARVO 2008, poster 930.
Percent of scans with fovea failures
Fovea not found Fovea not correct
11%
19%
24%
10%
18%
0%
CIRRUS HD-OCT User Manual
6%
10%
5%
6%
6%
0%