Adafruit ESP32-S3 Manual page 201

Often times you will get a warning like this, which is kind of vague:
No device found on COM66
An error occurred while uploading the sketch
This could be a few things.
First up, check again that you have the correct board selected! Many electronics
boards have very similar names or look, and often times folks grab a board different
from what they thought.
If you're positive the right board is selected, we recommend the next step is to put
the board into manual bootloading mode.
Native USB and manual bootloading
Historically, microcontroller boards contained two chips: the main micro chip (say,
ATmega328 or ESP8266 or ESP32) and a separate chip for USB interface that would
be used for bootloading (a CH430, FT232, CP210x, etc). With these older designs, the
microcontroller is put into a bootloading state for uploading code by the separate
chip. It allows for easier uploading but is more expensive as two chips are needed,
and also the microcontroller can't act like a keyboard or disk drive.
Modern chips often have 'native' USB - that means that there is no separate chip for
USB interface. It's all in one! Great for cost savings, simplicity of design, reduced size
and more control. However, it means the chip must be self-aware enough to be able
to put itself into bootload/upload mode on its own. That's fine 99% of the time but is
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