Safety Issues - Agilent Technologies G1992A User Manual

3 Safety

Safety Issues

Agilent designed the Nanospray Ion Source to minimize safety hazards:
However, you still need to be aware of several other potential safety issues
when you operate the Nanospray Ion Source.
Some of the procedures in this chapter require access to parts of the
instrument and Nanospray Ion Source while it is in Shutdown state or shortly
after it is turned off. If you do not perform these procedures correctly, you are
exposed to dangerous temperatures, voltages, and chemical hazards. This
topic describes the potential dangers.
Needle Hazard
The Nanospray Ion Source provides you with many options and configurations
for a wide range of experiments. This flexibility includes the ability to use
customer-drawn columns and needles. However, some combinations of needles
can be dangerous when used with the Nanospray Ion Source.
Use extreme caution when setting up experiments with any type of needle,
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especially conductive ones. Touching a high voltage region inside the Nanospray Ion
Source chamber with a conductive needle is extremely hazardous.
The needle in the needle holder is very sharp and can pierce your skin. Do not touch
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the tip, especially when you analyze toxic substances or when you use toxic
solvents.
The tip of the needle is very fragile. Do not touch the tip to any objects, such as the
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capillary cap or spray chamber. If you accidentally touch the needle tip, replace the
needle.
Use care when you adjust the needle. Do not damage the end of the needle.
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• ESI and nanospray needles are grounded.
• High voltage components are enclosed inside of chambers.
Nanospray Ion Source User Guide