Thermo Scientific Vanquish Operating Manual
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Thermo Scientific Vanquish Operating Manual

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Vanquish
Charger
Operating Manual
March 2023
4829.0001-EN Revision 2.0
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*4829.0001-EN-2.0*

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  • Page 1 Vanquish Charger Operating Manual March 2023 4829.0001-EN Revision 2.0 • *4829.0001-EN-2.0*...
  • Page 2 Copyright © 2023 Thermo Fisher Scientific Inc. All rights reserved. Original Operating Manual The hardware descriptions in this manual revision refer to devices: VH-A90-A. Trademarks Acrobat, Adobe, and Adobe Reader are trademarks of Adobe Systems Incorporated. Torx is a trademark of Acument Intellectual Properties, LLC. All other trademarks are property of Thermo Fisher Scientific and its subsidiaries.
  • Page 3 Contacting Us Contacting Us There are several ways to contact us: Ordering Information For ordering information or sales support for HPLC products, contact your local Thermo Fisher Scientific sales organization. For contact information, go to Contact Us on http://www.thermofisher.com. Technical Assistance For technical support for HPLC products, contact your local Thermo Fisher Scientific support organization.
  • Page 4 Contacting Us Page 4 Charger Operating Manual...

  • Page 5: Table Of Contents

    Contents Contents 1 Using this Manual................. 9 About this Manual .................... 10 Conventions ...................... 11 1.2.1 Conventions for Safety Messages ............ 11 1.2.2 Special Notices .................. 11 1.2.3 Typographical Conventions .............. 12 Reference Documentation...................  13 2 Safety .................. 15 Safety Symbols and Signal Words ................  16 2.1.1 Safety Symbols and Signal Words in this Manual........
  • Page 6 Contents 4 Unpacking ..................  33 Unpacking ...................... 34 Scope of Delivery .................... 36 5 Installation .................  37 Safety Guidelines for Installation .................  38 Site Requirements.................... 39 5.2.1 Power Considerations ................ 39 5.2.2 Power Cord.................... 39 5.2.3 Condensation ...................  40 6 Operation...................  41 Introduction to this Chapter ................
  • Page 7 Contents 8 Troubleshooting .................  67 General Information about Troubleshooting............ 68 Messages...................... 70 9 Specifications ................ 73 Performance Specifications .................  74 Physical Specifications .................. 75 10 Accessories, Consumables and Replacement Parts .....  77 10.1 General Information ....................  78 10.2 Ordering Information...................  79 11 Compliance Information .............
  • Page 8 Contents Page 8 Charger Operating Manual...

  • Page 9: Using This Manual

    • Using this Manual 1 Using this Manual This chapter provides information about this manual, the conventions used throughout the manual, and the reference documentation that is available in addition to this manual. Charger Page 9 Operating Manual...

  • Page 10: About This Manual

    Using this Manual About this Manual This manual describes the functional features and operating principle of your Vanquish™ device and provides instructions for installation, set up, start up, shut down, operation, maintenance and troubleshooting. This manual also contains safety messages, precautionary statements, and special notices.

  • Page 11: Conventions

    • Using this Manual Conventions This section describes the conventions that are used throughout this manual. 1.2.1 Conventions for Safety Messages The safety messages and precautionary statements in this manual appear as follows: • Safety messages or precautionary statements that apply to the entire manual and all procedures in this manual are grouped in the Safety chapter.

  • Page 12: Typographical Conventions

    • Using this Manual 1.2.3 Typographical Conventions These typographical conventions apply to the descriptions in this manual: Data Input and Output The following appears in bold type: • Input that you enter by the keyboard or that you select with the mouse •...

  • Page 13: Reference Documentation

    In addition to this operating manual, other documentation is available for reference. Hardware Documentation Additional hardware documentation includes the following: • Operating manuals for the other modules of the Vanquish system • Vanquish System Operating Manual • Instrument Installation Qualification Operating Instructions...
  • Page 14 • Using this Manual TIP The Chromeleon Help and documents are included in the software shipment. Third-Party Documentation Refer also to the user documentation provided by the manufacturers of third-party components and materials, for example, Safety Data Sheets (SDSs). Page 14 Charger Operating Manual...

  • Page 15: Safety

    • Safety 2 Safety This chapter provides general and specific safety information and informs about the intended use of the device. Charger Page 15 Operating Manual...

  • Page 16: Safety Symbols And Signal Words

    • Safety Safety Symbols and Signal Words 2.1.1 Safety Symbols and Signal Words in this Manual This manual contains safety messages to prevent injury of the persons using the device. The safety symbols and signal words in this manual include the following: Always be aware of the safety information.

  • Page 17: Safety Symbols On The Device

    • Safety 2.1.3 Safety Symbols on the Device The table lists the safety symbols that appear on the device or on labels affixed to the device. Follow the safety notices in this manual to prevent the risk of operator injury or damage to the device. Symbol Description Indicates a potential hazard.

  • Page 18: Intended Use

    Intended Use The device is intended to be part of the Vanquish system. The intended use of the Vanquish system is to analyze mixtures of compounds in sample solutions. The device is for use by qualified personnel and in laboratory environment only.

  • Page 19: Safety Precautions

    • Safety Safety Precautions 2.3.1 General Safety Information All users must observe the general safety information presented in this section and all specific safety messages and precautionary statements elsewhere in this manual during all phases of installation, operation, troubleshooting, maintenance, shutdown, and transport of the device. If the device is used in a manner not specified by Thermo Fisher Scientific, the protection provided by the device could be impaired.

  • Page 20: Personal Protective Equipment

    • Safety General Operation The device is designed to be operated only by trained and qualified personnel in a laboratory environment. All users must know the hazards presented by the device and the substances they are using. All users should observe the related Safety Data Sheets (SDSs).

  • Page 21: Electrical Safety Precautions

    Do not place liquid reservoirs directly upon the device. Liquid might leak into the device and get into contact with electronic components causing a short circuit. Instead, place liquid reservoirs in the solvent rack that is available for the Vanquish system. 2.3.5 General Residual Hazards...
  • Page 22 • Safety WARNING—Biohazard Biohazardous material, for example microorganisms, cell cultures, tissues, body fluids, and other biological agents can transmit infectious diseases. To avoid infections with these agents: • Assume that all biological substances are at least potentially infectious. • Wear personal protective equipment as required by the hazard and follow good laboratory practice.

  • Page 23: In Case Of Emergency

    • Safety WARNING—Explosion Hazard The air gap in the door seal of the device is an engineered safety feature designed to provide adequate air exchange inside the device. Blocking this port may result in the build-up of vapors inside the unit that can result in an explosion hazard.

  • Page 24: Compliance Information

    • Safety Compliance Information Thermo Fisher Scientific performs complete testing and evaluation of its products to ensure full compliance with applicable domestic and international regulations. When the device is delivered to you, it meets all pertinent electromagnetic compatibility (EMC) and safety standards as described in this manual.

  • Page 25: Device Overview

    • Device Overview 3 Device Overview This chapter introduces you to the device and the main components. Charger Page 25 Operating Manual...

  • Page 26: Charger Features

    Device Overview Charger Features The device stores sample racks and well plates, and transfers them to the Vanquish autosampler. It includes the following features: • A shelf to store sample racks and well plates. Different shelves are available for sample racks and well plates of variable heights.

  • Page 27: Operating Principle

    • Device Overview Operating Principle The mover is the transport system of the Charger. The mover shovel transports sample racks and well plates from the shelf to the free position in the autosampler carousel through a transfer opening in the right Charger side panel.

  • Page 28: Interior Components

    • Device Overview Interior Components The functional components of the device are located directly behind the front door: Figure 2: Interior view (door not shown) Description LED status indicators (on LED cover plate) Transfer opening to autosampler Magnetic door latch Mover Shelf locking rail Shelf 3.3.1...

  • Page 29: Shelf

    • Device Overview 3.3.2 Shelf Sample racks and well plates are placed in a shelf that is mounted on the base plate. The shelf is equipped with several guide rails (levels) to accommodate the sample racks and well plates. Each level is labeled with a number.

  • Page 30: Mover

    • Device Overview 3.3.3 Mover The mover is the transport system of the Charger. For details on how the mover operates, see Operating Principle (} page 27). The mover is equipped with a barcode reader to identify sample racks and well plates in the shelf as well as empty positions. Figure 4: Mover arm Description Barcode reader...

  • Page 31: Device Connections

    Main power switch (on/off control) with fuse holder Power-inlet connector USB port ("B" type connector) Allows connection to other modules in the Vanquish system or the computer on which the data system, such as the Chromeleon software, is installed. Label indicating the fuse and line rating.

  • Page 32: Operation

    For details, contact the Thermo Fisher Scientific sales organization. To control the Charger, a Vanquish autosampler must be installed and configured in the Chromeleon software. All functions for controlling the Charger are part of the autosampler control interface.

  • Page 33: Unpacking

    • Unpacking 4 Unpacking This chapter provides information for unpacking the device and informs you about the scope of delivery. Charger Page 33 Operating Manual...

  • Page 34: Unpacking

    • Unpacking Unpacking Damaged Packaging, Defective on Arrival Inspect the shipping container for signs of external damage and, after unpacking, inspect the device for any signs of mechanical damage that might have occurred during shipment. If you suspect that the device may have been damaged during shipment, immediately notify the incoming carrier and Thermo Fisher Scientific about the damage.
  • Page 35 Moving the Device after Installation If you have to move the device after it has been set up and installed in the Vanquish system, prepare the device for transport and move it to the new location. Follow the instructions in Transporting or Shipping the Device.

  • Page 36: Scope Of Delivery

    Scope of Delivery The following items are included in the delivery: • Vanquish Charger • Installation Kit including adapter frame for attaching the Charger to the Vanquish autosampler • USB cable (with ferrite bead) • Power cord • Printed operating manual •...

  • Page 37: Installation

    • Installation 5 Installation This chapter specifies the requirements for the installation site. Charger Page 37 Operating Manual...

  • Page 38: Safety Guidelines For Installation

    • Installation Safety Guidelines for Installation Pay attention to the following safety guidelines: Installation by Service Engineer only Service personnel certified by Thermo Fisher Scientific must perform the installation (for brevity, referred to as Thermo Fisher Scientific service engineer). Observe all warning messages and precautionary statements presented Safety Precautions (} page 19).

  • Page 39: Site Requirements

    Note the following: • Operate the device only under appropriate laboratory conditions. • The device is intended to be part of the Vanquish system. Observe the site requirements for the Vanquish system as stated in the Vanquish System Operating Manual. •...

  • Page 40: Condensation

    • Installation WARNING—Electric Shock or Damage to the Device • Never use a power cord other than the power cords provided by Thermo Fisher Scientific for the device. • Only use a power cord that is designed for the country in which you use the device.

  • Page 41: Operation

    • Operation 6 Operation This chapter describes the elements for device control, provides information for routine operation and for shutdown. Charger Page 41 Operating Manual...

  • Page 42: Introduction To This Chapter

    Thermo Fisher Scientific Technical Support for assistance. For a basic description of instrument control and automated sample analysis with the Chromeleon software, refer to the Vanquish System Operating Manual. Details on control and operation of the device are available in the Chromeleon Help.

  • Page 43: Safety Guidelines For Operation

    • Operation Safety Guidelines for Operation When operating the device, pay attention to the following safety guidelines: Observe all warning messages and precautionary statements presented Safety Precautions (} page 19). WARNING—Flammable and Hazardous Vapors from Spills Flammable or hazardous vapors from sample spills can accumulate inside the device.

  • Page 44: Control Elements

    • Operation Control Elements The device is designed to be operated from a computer running with the chromatography data system. In addition, status indicator LEDs on the front panel provide a quick visual check of the operational status of the device. 6.3.1 Status Indicators The status indicator LEDs at the front side of the device provide...

  • Page 45: Power Switch

    Turn the power off when instructed to do so in this manual; for example, before performing a maintenance procedure. The device cannot be turned on or off with the power button on the Vanquish system base. Figure 6: Power switch on left side TIP The Charger door is equipped with a mechanism that opens the door automatically when the device is turned off.

  • Page 46: Preparing The Device For Operation

    Selecting the Rack Type (} page 50)). • Make sure that the chromatography system is properly equilibrated. For more information, refer to the Vanquish System Operating Manual. 6.4.1 Temperature Control in the Charger Compartment Define the following parameters in the Chromeleon software if you want to use temperature control inside the Charger compartment to maintain the samples as required.

  • Page 47: Loading Sample Racks Or Well Plates

    • Operation 6.4.2 Loading Sample Racks or Well Plates WARNING—Flammable and Hazardous Vapors Flammable or hazardous vapors can escape from improperly sealed sample containers with flammable or volatile samples, and can accumulate inside the device. This can pose health and safety risks and lead to wrong results.
  • Page 48 Placing Sample Racks or Well Plates in the Shelf A barcode reader allows rack type identification of sample racks and well plates with a Vanquish rack type barcode. Figure 8: Sample rack with barcodes for rack type identification Description...
  • Page 49 Operation CAUTION—Positioning of Sample Racks or Well Plates without Barcode Sample racks and well plates without a Vanquish rack type barcode may easily be placed the wrong way around, but the Chromeleon software cannot detect the incorrect orientation. This may result in a safety hazard.

  • Page 50: Selecting The Rack Type

    Selecting the Rack Type The device automatically detects the container type for sample racks and well plates with a barcode for Vanquish rack type identification. You do not have to select a rack type. However, you must select a rack type for sample racks and well plates without such a barcode.

  • Page 51: Important Settings For Operation

    • Operation Important Settings for Operation The parameters described in this section should be considered for routine operation of the device. You can access these parameters from the Chromeleon user interface. For more information, refer to Chromeleon Help and documents. Setting Description Temperature Control...

  • Page 52: Shutting Down The Device

    • Operation Shutting Down the Device If the device will not be operated for a short or longer period of time, follow the instructions on shutting down the device in the following section. Shut down the Charger if the autosampler is shut down, too. If the autosampler is operating, leave the Charger turned on.

  • Page 53: Maintenance

    • Maintenance 7 Maintenance This chapter describes the routine maintenance procedures that the user may perform. Charger Page 53 Operating Manual...

  • Page 54: Introduction To Maintenance

    • Maintenance Introduction to Maintenance This chapter describes the routine maintenance procedures that the user may perform. Additional maintenance or service procedures must be performed only by service personnel certified by Thermo Fisher Scientific (for brevity, referred to as Thermo Fisher Scientific service personnel). Page 54 Charger Operating Manual...

  • Page 55: Safety Guidelines For Maintenance

    • Maintenance Safety Guidelines for Maintenance When performing maintenance procedures, pay attention to the following safety guidelines: Observe all warning messages and precautionary statements presented Safety Precautions (} page 19). WARNING—High Voltage High voltages are present inside the device that could cause an electric shock.

  • Page 56: Routine And Preventive Maintenance

    • Maintenance Routine and Preventive Maintenance Optimum device performance, maximum uptime of the device, and accurate results can be obtained only if the device is in good condition and properly maintained. 7.3.1 Maintenance Plan Perform the maintenance procedures in the table on a regular basis. The frequency given in the table is a suggestion.
  • Page 57 • Maintenance Parts required • Suitable cleaning detergent (or disinfectant) • Purified water • Lint-free cloths or wipes CAUTION—Explosive Gas Mixtures from Alcoholic Cleaning Detergents Alcohol-containing cleaning detergents may form flammable and explosive gas mixtures with air. • Use such cleaning detergents only when required and only in adequately ventilated rooms.
  • Page 58 • Maintenance Preparations 1. Turn off the power to the device and disconnect the power cord from the power source. 2. Remove the shelf and any samples from the compartment. Follow these steps 1. Wipe the surfaces clean with a clean, dry, soft, lint-free cloth or wipe.

  • Page 59: Updating The Device Firmware

    1. Read the release notes provided with the firmware and/or Chromeleon version. 2. Verify that the Charger check box on the General page of the Vanquish Autosampler configuration is selected. 3. Connect the autosampler in the Chromeleon software. 4. Stop all operations on the Instrument that includes the device.
  • Page 60 1. Turn the device off, wait for 5 seconds and turn it on again. 2. Run a short sequence from the Chromeleon software to see if the mover can access the shelf and the Vanquish autosampler as expected. If the device does not operate as expected, contact Thermo Fisher Scientific Technical Support for assistance.

  • Page 61: Transporting Or Shipping The Device

    (for brevity, referred to as Thermo Fisher Scientific service engineer). • If it is required to reattach the Charger to the Vanquish autosampler after transport, contact Thermo Fisher Scientific Technical Support for assistance. Observe all warning messages and precautionary statements presented Safety Precautions (} page 19).

  • Page 62: Preparing The Device For Transport

    • Maintenance 7.5.1 Preparing the Device for Transport To prepare the device for transport, follow these steps: 1. Shut down the device as described in Shutting Down the Device (} page 52). In particular, verify that the shelf and any samples were removed from the compartment before you continue.
  • Page 63 • Maintenance Figure 11: Removing the LED Cover Plate 6. Follow the steps below to protect the mover during shipment using the original shipping lock screws and foam parts that were removed during initial installation: a) Place foam part 1 below the mover arm and lower the mover arm to the lowest position, such that the shovel and mover arm rest in the cavities of the foam part.
  • Page 64 Figure 13: Shipping lock screws securing the mover c) Install foam parts 2, 3, and 4. 7. Remove the Charger from the Vanquish system. 8. In order to continue operating the autosampler without the Charger, mount the metal cover plate to the opening on the autosampler enclosure.

  • Page 65: Transporting The Device To A New Location

    • Maintenance 7.5.2 Transporting the Device to a New Location The Charger must be transported in upright position under the following conditions: • The shelf and all sample racks or well plates have been removed from the compartment. • The mover shovel has been lowered to the lowest position, and the mover is secured with the shipping lock screws and foam parts.
  • Page 66 • Maintenance Page 66 Charger Operating Manual...

  • Page 67: Troubleshooting

    • Troubleshooting 8 Troubleshooting This chapter is a guide to troubleshooting issues that may arise during operation of the device. Charger Page 67 Operating Manual...

  • Page 68: General Information About Troubleshooting

    TIP For information about operating issues that might occur during the operation of a Vanquish system, refer to the Vanquish System Operating Manual. If you are unable to resolve a problem following the instructions given here or if you experience problems that are not covered in this section, contact Thermo Fisher Scientific Technical Support for assistance.
  • Page 69 • Troubleshooting Power Failure After a power failure, the device door is opened automatically. Remove the shelf and look inside the device compartment. If there is a sample rack or well plate on the shovel, place it back on the shelf or remove it. Execute a Reset command in the Chromeleon software (SamplerModule) before you restart the Queue.

  • Page 70: Messages

    • Troubleshooting Messages The table lists the most frequently observed messages for the device and provides troubleshooting assistance. If you are unable to resolve the problem following the instructions, contact Technical Support for assistance. TIP If a message appears in the Audit Trail that is not listed in the table, write down the code and wording of the message.
  • Page 71 • Troubleshooting Message Description and Remedial Action ATTENTION: A rack was added to shelf This message occurs when you place a new sample rack or well position CH{0:d2}, which is already in plate in the Charger while a sequence is running. Remove the use: The corresponding rack is currently sample rack or well plate immediately from the device.
  • Page 72 • Troubleshooting Message Description and Remedial Action Error: The rack/plate on shelf position Place each sample rack or well plate so that position A1 is at the CHXX is placed the wrong way around front right-hand corner, see also Loading Sample Racks or Well and cannot be used for injection.

  • Page 73: Specifications

    • Specifications 9 Specifications This chapter provides the physical and performance specifications of the device. Charger Page 73 Operating Manual...

  • Page 74: Performance Specifications

    • Specifications Performance Specifications The device performance is specified as follows: Type Specification Temperature range 4-40 °C (settable), cooling target ≤ 22 K below ambient Temperature accuracy -2 °C / +4 °C Spatial temperature deviation ±2 °C Plate capacity 9 deep well plates, maximum height 45 mm or 9 sample racks, maximum height 45 mm including vials or 20 well plates, maximum height 20 mm Sample capacity...

  • Page 75: Physical Specifications

    • Specifications Physical Specifications The physical conditions of the device are specified as follows: Type Specification Range of use Indoor use only Ambient temperature Operation: 5 °C to 35 °C Storage: 1 °C to 60 °C Transport: -20 °C to 60 °C Ambient humidity Operation: 20% to 80% relative humidity, non-condensing Storage: 5% to 80% relative humidity, non-condensing...
  • Page 76 • Specifications Page 76 Charger Operating Manual...

  • Page 77: Accessories, Consumables And Replacement Parts

    • Accessories, Consumables and Replacement Parts 10 Accessories, Consumables and Replacement Parts This chapter provides information for reordering accessories, consumables, and replacement parts. Charger Page 77 Operating Manual...

  • Page 78: General Information

    • Accessories, Consumables and Replacement Parts 10.1 General Information The device must be operated only with the replacement parts and additional components, options, and peripherals specifically authorized and qualified by Thermo Fisher Scientific. Accessories, consumables, and replacement parts are always maintained at the latest technical standard.

  • Page 79: Ordering Information

    • Accessories, Consumables and Replacement Parts 10.2 Ordering Information For ordering information of sample racks and well plates for the device, refer to the information that is included in the Vanquish autosampler ship kit. Shelves Description Part No. Shelf for 9 deep well plates and/or sample racks 6900.1020...
  • Page 80 • Accessories, Consumables and Replacement Parts Page 80 Charger Operating Manual...

  • Page 81: Compliance Information

    • Compliance Information 11 Compliance Information This chapter provides additional compliance information. Charger Page 81 Operating Manual...

  • Page 82: Declarations Of Conformity

    • Compliance Information 11.1 Declarations of Conformity CE Declaration of Conformity The device has satisfied the requirements for the CE mark and is compliant with the applicable requirements. UL/CSA 61010-1 Compliance The label of the NRTL Lab on the device (for example, cTUVus or CSA mark) indicates that the device has satisfied the requirements of the applicable standards.

  • Page 83: Weee Compliance

    • Compliance Information 11.2 WEEE Compliance This product is required to comply with the European Union’s Waste Electrical & Electronic Equipment (WEEE) Directive. It is marked with the following symbol: Figure 14: WEEE symbol Thermo Fisher Scientific has contracted with one or more recycling or disposal companies in each European Union (EU) Member State, and these companies should dispose of or recycle this product.

  • Page 84: Fcc Compliance

    • Compliance Information 11.3 FCC Compliance This equipment has been tested and found to comply with the limits for a Class A digital device, pursuant to part 15 of the U.S. FCC Rules. These limits are designed to provide reasonable protection against harmful interference when the equipment is operated in a commercial environment.

  • Page 85: Manual Release History

    • Compliance Information 11.4 Manual Release History Revision Covering VH-A90-A 1.0a VH-A90-A VH-A90-A The instructions were prepared in English (original instructions). Other language versions are translations based on the English original instructions. Charger Page 85 Operating Manual...
  • Page 86 • Compliance Information Page 86 Charger Operating Manual...

  • Page 87: Index

    Index Index accessories ............ 77 gloves...............  20 audit trail............ 68 guidelines Audit Trail messages ........ 70 installation.......... 38 operation ............  43 barcode ............ 48 barcode reader.......... 30 installation safety guidelines.........  38 site requirements ........ 39 Instrument Audit Trail ........ 68 CE mark ............ 82 intended use............  18 Chromeleon............ 32 interior view ............
  • Page 88 Index LEDs............. 44 qualification of personnel...... 19 load samples .......... 47 safety symbols ...........  16, 17 power on/off .......... 45 sample position .......... 51 rack type.......... 50, 51 sample rack............ 47 restart............ 52 barcode............ 48 safety guidelines ......... 43 orientation.......... 49 sample rack orientation ...... 49 rack type .......... 50, 51 shelf............. 47 scope of delivery..........
  • Page 89 Index orientation .......... 49 rack type.......... 50, 51 Charger Page 89 Operating Manual...
  • Page 90 www.thermofisher.com Thermo Fisher Scientific Inc. 168 Third Avenue Waltham Massachusetts 02451...

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